Credit: Image courtesy of NIEHS
Mice with higher levels of TTP are protected against arthritic inflammation. Stained sections of foot joints from wild-type (left) and TTP+ (right) mice show that when both were tested using a model of rheumatoid arthritis, the wild-type mouse experienced significant inflammation. Arrows indicate the presence of inflammatory immune cells in tissues lining the joints. The mouse with higher amounts of TTP did not exhibit inflammation.