Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease Yosef Koronyo ... Keith L. Black, Maya Koronyo-Hamaoui Published August 17, 2017 Citation Information: JCI Insight. 2017;2(16):e93621. doi:10.1172/jci.insight.93621
Cedars-Sinai neuroscience investigators have found that Alzheimer’s disease affects the retina – the back of the eye – similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer’s disease years before patients experience symptoms. Using a high-definition eye scan developed especially for the study, researchers detected the crucial warning signs of Alzheimer’s disease: amyloid-beta deposits, a buildup of toxic proteins. The findings represent a major advancement toward identifying people at high risk for the debilitating condition years sooner.