Credit: Figure by James Wang
Figure 1. Schematic of microshells enhancing HIFU in a potential glioblastoma clinical setting.
Glioblastoma tumors initially suppress the immune system. Microshells enhanced image-guided HIFU to blow up the tumors and release tumor antigens. Simultaneous systemic blocking of PD-1, the break on T cells re-awakens the immune system to establish tumor immunity.