Justin Poling and Christine Iacobuzio-Donahue.
Ki67 labeling of normal colon resections. Shown are examples of Ki67 (A, B, C, D) labeling in a 26 year old individual (A-B) compared to an 80 year old individual (C-D). In each image, lu indicates the location of the colonic lumen, cr indicates a properly oriented crypt, and mm indicates the muscularis mucosae. The crypts outlined in (A) and (C) are magnified in (B) and (D), respectively. Arrows indicate antibody-labeled nuclei, which are outlined in red. Images in (A, C) were taken at 100x while those in (B, D) were taken at 400x.