Photo by Cedars-Sinai
"We revealed early molecular and cellular loss in blood vessels together with accumulation of amyloid-beta deposits, a buildup of a toxic protein, in retinal blood vessel walls of Alzheimer's patients." said the study's senior and corresponding author Maya Koronyo-Hamaoui, PhD, associate professor of Neurosurgery and Biomedical Sciences at Cedars-Sinai. "The buildup of this protein in the brain is a signature of Alzheimer's. We were able to map these vascular abnormalities and find that certain regions of the retina were more vulnerable."