Credit: © 2020 Kim et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20200533
Pancreatic tissue from a type 1 diabetic mouse (left) shows large numbers of infiltrating immune cells and a reduction in the size of β cell–containing islets of Langerhans (yellow arrows). These symptoms are prevented by deletion of the gene encoding OCA-B (right).