Newswise — Rockville, Md. (January 17, 2024)—More than half of adults living in the U.S. label themselves as “mouth breathers”—breathing primarily through an open mouth. However, according to new research published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, breathing through the nose leads to several benefits, including lower blood pressure and other factors that could predict heart disease risk. The study was chosen as an APSselect article for January.

Cardiovascular disease is the number one cause of death in the U.S. Blood pressure and heart rate can be predictors of heart disease. Breathing patterns can affect these bodily functions due to the crosstalk that occurs between the respiratory and cardiovascular systems. Nasal breathing has been shown to relax the airways and improve breathing efficiency, but the effects of breathing through the nose on the cardiovascular system are less clear.

A group of 20 young adult volunteers participated in a crossover study consisting of rest and exercise conditions. In the rest condition, the volunteers performed both nasal-only and mouth-only breathing activities in a randomized order. First, they sat quietly for five minutes and then breathed for five minutes at their own pace. Nasal breathing was performed with the lips closed; mouth breathing was done with soft nose clips to prevent nasal airflow.

The exercise condition was meant to mimic the activity of daily living of walking at a moderate pace at a slight incline. The volunteers breathed, also in a randomized order, at their own rate for seven minutes while using a recumbent stationary bike. As with the rest condition, one activity involved mouth-only breathing and the other, nasal-only breathing. The research team measured the volunteers’ blood pressure, blood oxygen levels and heart rate during each condition.

The research team found that the volunteers’ diastolic blood pressure was lower when they breathed through the nose and a lower perceived rate of exertion than when they breathed through the mouth in the rest condition, but not exercise condition. In addition, nasal breathing shifted the nervous system into a more parasympathetic state (“rest and digest” rather than “flight or fight”) during the rest condition.

“We interpret the collective data to suggest that nasal compared with oral breathing provides modest, but potentially clinically relevant, improvements in prognostic cardiovascular variables at rest, but not during exercise,” the researchers wrote. “This work advances our knowledge of how nasal breathing affects clinically relevant cardiovascular variables and provides foundational acute data in healthy young adults to justify future longer-term studies in other populations.”

Read the full article, “Acute nasal breathing lowers diastolic blood pressure and increases parasympathetic contributions to heart rate variability in young adults,” published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. The article is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program. Read all of this month’s selected research articles.


NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact APS Media Relations or call 301.634.7314. Find more research highlights in our Newsroom.

Physiology is a broad area of scientific inquiry that focuses on how molecules, cells, tissues and organs function in health and disease. The American Physiological Society connects a global, multidisciplinary community of more than 10,000 biomedical scientists and educators as part of its mission to advance scientific discovery, understand life and improve health. The Society drives collaboration and spotlights scientific discoveries through its 16 scholarly journals and programming that support researchers and educators in their work.

Journal Link: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology