Researchers Explore How Protein Production Works in Muscle with or without Its Typical Signaling

Article title:The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy - a potential role for mTORC1

Authors: Michael Tabbaa, Tania Ruz Gomez, Dean G. Campelj, Paul Gregorevic, Alan Hayes, Craig A. Goodman

From the authors: “This study examined changes in polyamine pathway proteins during muscle hypertrophy induced by mechanical overload, with and without the mTORC1 inhibitor, rapamycin and during muscle atrophy induced by food deprivation (48 hours) and denervation (7 days) in mice.”

This study is highlighted as one of June’s “best of the best” as part of the American Physiological Society's APSselect program.