Research Alert

Article title: Antithrombotic effects of heme-degrading and heme-binding proteins

Authors: Karl A. Nath, Joseph P. Grande, John D. Belcher, Vesna D. Garovic, Anthony J. Croatt, Matthew L. Hillestad, Michael A. Barry, Meryl C. Nath, Raymond F. Regan, Gregory M. Vercellotti

From the authors: “This study provides conclusive evidence that two proteins, one heme-degrading and the other heme-binding, inhibit clot formation. This may serve as a new therapeutic strategy in preventing and treating venous thromboembolic disease.” 

This study is highlighted as one of April's "best of the best" as part of the American Physiological Society's APSselect program.

Journal Link: American Journal of Physiology- Heart and Circulatory Physiology