Impaired Chloride Absorption Due to Decreased Protein Expression May Contribute to Diarrheal Disease

Article title: "Decreased SLC26A3 expression and function in intestinal epithelial cells in response to Cryptosporidiium parvum infection"

Authors: Anoop Kumar, Dulari Jayawardena, Arivarasu N. Anbazhagan, Ishita Chatterjee, Shubha Priyamvada, Waddah A. Alrefai, Alip Borthakur, Pradeep K. Dudeja

From the authors: "Our results suggest that impaired chloride absorption due to downregulation of DRA could be one of the contributing factors to CP-induced acute, self-limiting diarrhea in immunocompetent hosts." 

From the editor: "This study on an important contributing factor to cryptosporidiosis (diarrheal disease)-related pathology."