Newswise — New research shows that children between 8 and 15 years old who are in the upper half of the normal weight range are more likely than their leaner peers to become obese or overweight as young adults. This research was conducted over nearly a decade at the Harvard Medical School (HMS) and Harvard Pilgrim Health Care Department of Ambulatory Care and Prevention and Children's Hospital Boston and is reported in this month's Obesity Research journal.

"We have known that kids who are overweight or obese have a higher risk for being overweight or obese as adults. But in this paper, we show that even children in the high normal weight range have an elevated risk of becoming overweight or obese as adults," said lead author Alison Field, assistant professor of pediatrics at HMS and Children's Hospital Boston.

According to the Centers for Disease Control and Prevention's national reference data, children with a BMI between the national 85th and 95th percentiles for age and gender are classified as at risk for being overweight, and those with a BMI greater than the 95th percentile are classified as overweight. The authors considered a body mass index (BMI) between the 50th and 84th percentile to be in the high normal weight range.

The study comprised 314 children, mostly Caucasian, from East Boston, MA, who were 8 to 15 years old when their weight, height, and blood pressure were first recorded. They were again evaluated 8 to 12 years later. Results showed that nearly half of the male subjects (48.3 percent) and nearly a quarter of the female subjects (23.5 percent) became overweight or obese between their first childhood visit and the young adult follow-up. Compared with children with a BMI less than the 50th percentile, girls and boys between the 50th and 74th percentile were five times more likely to become overweight. Boys and girls with a BMI between the 75th and 84th percentile were up to 20 times more likely to become overweight as young adults.

The results also showed that among the boys, elevated BMI in childhood predicted risk of high blood pressure (hypertension) in young adulthood. Compared with boys who had a childhood BMI below the 75th percentile, boys between the 75th and 85th percentile of BMI as children were four times more likely to become hypertensive. Boys at or above the 85th percentile were five times more likely to become hypertensive.

"There has been widespread recognition in the past few years of how important it is to prevent obesity in children. These findings underscore that even children who are in the high normal weight range may have adverse outcomes later in life, and our challenge may be even greater than we thought," said Matthew Gillman, senior author on the paper and associate professor of ambulatory care and prevention at HMS. "We must focus not only on the most obese kids but also on those who are just a bit overweight."

Access the Centers for Disease Control and Prevention's BMI charts for children and teens:http://www.cdc.gov/nccdphp/dnpa/bmi/bmi-for-age.htm

HARVARD MEDICAL SCHOOLhttp://hms.harvard.edu/Harvard Medical School has more than 5,000 full-time faculty working in eight academic departments based at the School's Boston quadrangle or in one of 47 academic departments at 18 Harvard teaching hospitals and research institutes. Those Harvard hospitals and research institutions include Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Cambridge Health Alliance, the CBR Institute for Biomedical Research, Children's Hospital Boston, Dana-Farber Cancer Institute, Forsyth Institute, Harvard Pilgrim Health Care, Joslin Diabetes Center, Judge Baker Children's Center, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, Massachusetts Mental Health Center, McLean Hospital, Mount Auburn Hospital, Schepens Eye Research Institute, Spaulding Rehabilitation Hospital, VA Boston Healthcare System.

CHILDREN'S HOSPITAL BOSTONChildren's Hospital Boston is the nation's leading pediatric medical center, the largest provider of health care to Massachusetts' children, and the primary pediatric teaching hospital of Harvard Medical School. Children's provides pediatric and adolescent health services for patients from birth through age 21. In addition to 325 inpatient beds and comprehensive outpatient programs, it houses the world's largest research enterprise based at a pediatric medical center. More than 500 scientists, including eight members of the National Academy of Sciences, nine members of the Institute of Medicine and 10 members of the Howard Hughes Medical Institute comprise Children's research community. For more information about the hospital visit: http://www.childrenshospital.org.

HARVARD PILGRIM HEALTH CAREhttp://www.hphc.orgHarvard Pilgrim Health Care is a not-for-profit health care plan operating in Massachusetts, New Hampshire, and Maine with a network of more than 22,000 doctors, 130 hospitals, and more than 800,000 members. Harvard Pilgrim was the first New England health plan to establish a non-profit foundation with the sole purpose of serving the community at large. The efforts of the foundation reflect Harvard Pilgrim's mission, which is to improve the health of its members and the health of society.

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CITATIONS

Obesity Journal (Mar-2005)