Newswise — January 30, 2019Plastic surgeons have long debated the mechanisms aging-related changes in the face: Are they related more to "deflation" or "sagging"? A new study helps settle the debate, showing significant loss of volume in the upper lip in older adults, reports the February issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

"Our results suggest that the aging perioral area is affected with a combination of soft tissue lengthening, thinning, and volume loss," concludes the new research, led by Patrick L. Tonnard, MD, PhD, of Coupre Centre for Plastic Surgery, Ghent, Belgium. For plastic surgeons, the findings may help to inform and improve evidence-based approaches to facial rejuvenation.

MRI Scans Lend Insight into Aging-Related Changes in the Upper Lip

The researchers analyzed magnetic resonance imaging (MRI) scans of the head obtained for other reasons in 200 adults: 100 women and 100 men. Participants were divided into a younger group aged 20 to 30 and an older group aged 65 to 80. Detailed measurements of the "upper lip unit" were analyzed to evaluate differences between the two groups, with an average age difference of nearly 50 years.

The measurements revealed several age-related differences in the anatomy of the upper lip. These included significant lengthening of the upper lip in older adults: about 19 percent longer in women and 18 percent longer in men, compared to the younger group.

The older group also had decreased soft tissue thickness of the upper lip: by about 41 percent in women and 33 percent in men. Most of the reduction in tissue thickness occurred at the "alar nasolabial fold" – the top of the lines running from the base of the nose to the corners of the lips.

The findings suggest that age-related lengthening and thinning of the upper lip represents more than just "sagging."  Dr. Tonnard and colleagues write, "[V]olume loss is an obvious feature of the aging upper lip." Loss of soft tissue volume also seems to contribute to deepening of the nasolabial folds, a prominent feature of the aging face.

"The mouth and perioral area play a primary role in emotional expression and attractiveness of the face," according to the authors. "Unfortunately, the mechanisms of centrofacial aging are poorly understood" – as illustrated by the debate over "sagging versus deflation." The new study provides insights into these mechanisms, based on detailed MRI measurements in a large sample of older versus younger adults.

Lengthening, thinning, and volume loss all contribute to aging of the area around the mouth, the study suggests. The findings add to the evidence base underlying plastic surgery and other cosmetic procedures for facial rejuvenation. Dr. Tonnard and colleagues plan a follow-up article to discuss the clinical implications of their findings, including the role of dermal fillers for minimally invasive volume augmentation.

Click here to read "Aging of the Upper Lip"

DOI: 10.1097/PRS.0000000000005190

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Plastic and Reconstructive Surgery® is published in the Lippincott portfolio by Wolters Kluwer.

About Plastic and Reconstructive Surgery

For more than 70 years, Plastic and Reconstructive Surgery® (http://www.prsjournal.com/) has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. The official journal of the American Society of Plastic Surgeons, Plastic and Reconstructive Surgery® brings subscribers up-to-the-minute reports on the latest techniques and follow-up for all areas of plastic and reconstructive surgery, including breast reconstruction, experimental studies, maxillofacial reconstruction, hand and microsurgery, burn repair and cosmetic surgery, as well as news on medico-legal issues.

 About ASPS

The American Society of Plastic Surgeons is the largest organization of board-certified plastic surgeons in the world. Representing more than 7,000 physician members, the society is recognized as a leading authority and information source on cosmetic and reconstructive plastic surgery. ASPS comprises more than 94 percent of all board-certified plastic surgeons in the United States. Founded in 1931, the society represents physicians certified by The American Board of Plastic Surgery or The Royal College of Physicians and Surgeons of Canada.

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Plastic and Reconstructive Surgery