Research Alert

Article title: A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics

Authors: Olivia C. Rivera, Donna T. Geddes, Shiran Barber-Zucker, Raz Zarivach, Annie Gagnon, David I. Soybel, Shannon L. Kelleher

From the authors: “Our findings demonstrate the Thr288Ser mutation in SLC30A2/ZnT2 impairs critical functions of mammary epithelial cells, and suggest a role for genetic variation in the regulation of milk production and lactation performance.” 

This study is highlighted as one of June’s "best of the best" as part of the American Physiological Society's APSselect program.

Journal Link: American Journal of Physiology - Cell Physiology