American Thoracic Society (ATS)

ATS Statement on Latest COVID-19 Policy Actions: Convalescent Plasma and Testing of Asymptomatic Patients

Newswise — Aug. 28, 2020 -- The American Thoracic Society is alarmed by two federal agency policy actions that may significantly impact our nation’s COVID-19 response. This week, the FDA issued an emergency use authorization (EUA) for the use of convalescent plasma to treat COVID-19 disease.  This action was taken despite a lack of adequate evidence demonstrating a clear benefit for most patients. As pulmonary and critical care clinicians and researchers who treat individuals with COVID-19, we are concerned that an EUA for convalescent plasma has the potential to put patients at risk. 

While convalescent plasma currently indicates promise as a treatment for some patients with COVID-19, more study is needed to determine who might benefit from treatment, when treatment is most effective and what risks might accrue to patients treated with it. Answers to these important questions will only be gained through rigorous clinical trials, ideally randomized controlled trials.  However, this EUA may discourage enrollment in clinical trials, may lead to use in low-volume settings where outcomes are generally worse, and may limit monitoring of adverse treatment outcomes.

We are also deeply concerned that the lack of transparency surrounding the EUA announcement has undermined the scientific credibility of the FDA. The ATS urges the FDA to publicly disclose the evidence base for issuing the EUA in the context of concerns raised by the scientific community, including the NIH leadership, to reassure the community and ensure public confidence in the FDA decision making process.

Secondly, the ATS is gravely concerned by the CDC’s revised guidance on COVID-19 testing. Public health evidence clearly indicates that asymptomatic individuals are important source vectors of SARS-CoV2 community transmission. Testing asymptomatic individuals who are close contacts of those known to have COVID-19 infection is an evidence-based public health intervention that slows infectious disease transmission, along with other critical interventions including contact tracing and isolation.  It is unclear what the scientific rationale is for changes that will lead to reduced testing of asymptomatic close contacts of COVID-19 positive individuals.

In addition, the revised CDC guidance was communicated to the public with insufficient clarification and little supporting evidence, leaving important interpretation to the lay press and general public, resulting in confusion for health professionals and the public. Changes in guidance without a clear scientific basis undermine trust in the CDC, our nation’s frontline public health agency, and has the potential to further hinder our COVID-19 response.

 The ATS recommends that the CDC restore the previous guidance on COVID testing and further, articulate a comprehensive plan for testing, contact tracing and isolation that minimizes community spread of SARS-CoV2. Finally, the ATS urges the Administration to adopt a comprehensive communication strategy that reinforces public confidence that decision-making on our pandemic response is driven by science and evidence-based public health practice, not politics.

 Share Via Twitter:
@atscommunity is deeply concerned by recent actions by @US_FDA and @CDCgov. Read our statement: WWW.THORACIC.ORG/covid/atscovid19-082820.pdf




Filters close

Showing results

110 of 4156
Newswise: Stimulus Relief Funds Increase Social Distancing to Stop Spread of COVID-19
23-Nov-2020 5:20 PM EST
Stimulus Relief Funds Increase Social Distancing to Stop Spread of COVID-19
University of California San Diego

As case rates of COVID-19 reach new heights across the nation, many states and cities are tightening stay-at-home restrictions to stop the spread. New research suggests that that those suffering from economic hardships are less likely comply with new stay-at-home orders; however these same U.S. residents would be more likely to adhere to the new public health guidelines if their households received stimulus funds.

access_time Embargo lifts in 2 days
Embargo will expire: 1-Dec-2020 9:15 AM EST Released to reporters: 30-Nov-2020 2:30 PM EST

A reporter's PressPass is required to access this story until the embargo expires on 1-Dec-2020 9:15 AM EST The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Newswise:Video Embedded covid-19-update-surge-preparedness-vaccine-distribution
VIDEO
Released: 30-Nov-2020 2:20 PM EST
COVID-19 Update: Surge Preparedness, Vaccine Distribution
Cedars-Sinai

With the novel coronavirus spreading across the U.S. at a record pace, Cedars-Sinai has been seeing an increase in COVID-19 patients at its hospitals and through its network of physicians. But the health system's leaders say Cedars-Sinai is prepared.

Released: 30-Nov-2020 1:20 PM EST
Rethink COVID-19 infection control to keep primary schools open this winter, governments urged
BMJ

An urgent rethink of infection control policies to keep COVID-19 infection at bay in schools is needed if primary schools are to be kept open this winter, and the knock-on effects on their families avoided, argue children's infectious disease specialists in a viewpoint, published online in the Archives of Disease in Childhood.

Newswise: Hackensack University Medical Center Urologists Continue to Provide State-of-the-Art Care During COVID-19
Released: 30-Nov-2020 12:45 PM EST
Hackensack University Medical Center Urologists Continue to Provide State-of-the-Art Care During COVID-19
Hackensack Meridian Health

Don’t Delay Your Care – Our dnhanced pandemic safety precautions prioritize patient health and allow providers to deliver outstanding in-office, telehealth and surgical care

Released: 30-Nov-2020 12:10 PM EST
Struggles of care home staff during COVID-19 first wave revealed in Whatsapp messages
University of Leeds

Analysis of social media messages between care home staff on the coronavirus front line reveal their growing concerns over how to manage in the face of the virus.

Released: 30-Nov-2020 11:30 AM EST
More than one-third of children with COVID-19 show no symptoms: study
University of Alberta Faculty of Medicine & Dentistry

More than one-third of kids who have COVID-19 are asymptomatic, according to a University of Alberta study that suggests youngsters diagnosed with the disease may represent just a fraction of those infected.

Newswise: Promising lab results in quest to find naturally occurring anti-COVID therapies
24-Nov-2020 5:35 PM EST
Promising lab results in quest to find naturally occurring anti-COVID therapies
University of Alabama Huntsville

So far, 35 of 125 naturally occurring compounds identified computationally at The University of Alabama in Huntsville (UAH) to have potential against COVID-19 have shown efficacy in ongoing first-batch testing at the University of Tennessee Health Science Center’s Regional Biocontainment Laboratory (UTHSC RBL) that’s the next step in the process to becoming a drug.

Released: 30-Nov-2020 9:45 AM EST
Rutgers Leading Coronavirus Therapeutic Clinical Trial
Rutgers University-New Brunswick

Rutgers is leading a clinical trial assessing the efficacy of a three-drug combination in treating people infected with SARS-CoV-2 and asymptomatic or mildly symptomatic.


Showing results

110 of 4156

close
1.10335