BIDMC’s Research & Health News Digest – July 2020 Edition

Beth Israel Lahey Health

Welcome to the July 2020 Edition of Beth Israel Deaconess Medical Center’s (BIDMC) Research & Health News Digest. 

 

Breaking news: Single-shot COVID-19 vaccine protects non-human primates

This morning, a group of scientists, led by BIDMC’s Dan H. Barouch, MD, PhD, reported in Nature that a leading candidate COVID-19 vaccine developed at BIDMC in collaboration with Johnson & Johnson raised neutralizing antibodies and robustly protected non-human primates against SARS-CoV-2, the virus that causes COVID-19. Read more, here:

https://www.bidmc.org/about-bidmc/news/2020/07/covid-19-vaccine-protects-non-human-primates

 

Additional stories in this edition include:

  • Study: Delaying surgery associated with increased risk in some gastrointestinal malignancies
  • Respirators may be disinfected up to 20 times without loss of fit or filtration
  • National survey on COVID-19 pandemic shows significant mental health impact
  • Physicians provide first comprehensive review of COVID-19’s effects beyond the lungs
  • Study finds significant decline in emergent medical, surgical and obstetric hospitalizations during early phase of COVID-19 public health emergency at BIDMC
  • Mask-related acne tips from a dermatologist
  • Study reveals increasing rates of preventable hospitalizations among older adults with dementia
  • Researchers work to better measure delirium severity in older patients
  • Researchers find end-of-life practices vary widely by region
  • Heat-related injuries and how to stay cool
  • Screening for Hepatitis C: Not just for baby boomers
  • Dealing with Crohn's Disease during pregnancy

 

Study: Delaying surgery associated with increased risk in some gastrointestinal malignancies

In a study published in the Journal of Gastrointestinal Surgery, a team of investigators led by Scott Fligor, MD, (General Surgery, BIDMC) examined the effects of delaying surgery for gastrointestinal cancers and found that the delays may be associated with shorter survival times.

https://www.bidmc.org/about-bidmc/news/2020/07/surgical-delay

 

Respirators may be disinfected up to 20 times without loss of fit or filtration

As infection rates begin to spike in some regions around the country, a team of microbiologists led by James E. Kirby, MD, (Clinical Microbiology Laboratory, BIDMC), identified an efficient, low-cost method of disinfecting N95 respirators for re-use up to 20 times. Their findings, which could help alleviate shortages among health care providers, are published online in mBio.

https://www.bidmc.org/about-bidmc/news/2020/07/respirators-disinfected

 

National survey on COVID-19 pandemic shows significant mental health impact

The findings of a nationwide survey deployed by Sarah Ballou, PhD (Gastroenterology, BIDMC) and colleagues show 90 percent of survey respondents reported experiencing emotional distress related to the pandemic.

https://www.bidmc.org/about-bidmc/news/2020/07/covid-19-mental-health

 

Physicians provide first comprehensive review of COVID-19’s effects beyond the lungs

Researcher-clinicians, including Kartik Sehgal, MD, (Cancer Center, BIDMC), conducted an extensive review of the latest findings on COVID-19’s effect on organ systems outside the lungs. Their review, published in Nature Medicine, also summarized proposed mechanisms behind these wide-ranging systemic effects and provided clinical guidance for physicians.

https://www.bidmc.org/about-bidmc/news/2020/07/covid-19-effects-beyond-the-lungs

 

Study finds significant decline in emergent medical, surgical and obstetric hospitalizations during early phase of COVID-19 public health emergency at BIDMC

In a study published in the Journal of General Internal MedicineTimothy Anderson, MD, (General Medicine, BIDMC) and colleagues report on the decline of emergent medical, surgical and obstetric hospitalizations at the medical center during the six-week period following the week of the declaration of the COVID-19 public health emergency in Boston in mid-March 2020.

https://www.bidmc.org/about-bidmc/news/2020/07/covid-hospital-declines

 

Mask-related acne tips from a dermatologist

With the CDC’s recommendation to wear cloth face coverings in public to help reduce the spread of COVID-19, people may find themselves facing new or increased skin complaints. Rachel Reynolds, MD, (Dermatology, BIDMC) shares what concerns she is hearing most often from patients, and steps you can take to soothe your skin.

https://www.bidmc.org/about-bidmc/wellness-insights/skin-health/mask-related-acne-tips-from-a-dermatologist

 

Study reveals increasing rates of preventable hospitalizations among older adults with dementia

Older adults with dementia tend to be hospitalized more often than those without cognitive impairment. Timothy Anderson, MD (Medicine, BIDMC) and colleagues have found that in recent years, increasing numbers of these hospitalizations were for conditions for which hospitalization can often be avoided with improvements in outpatient care. The findings, published in the Journal of the American Geriatric Society, point to the need for improved strategies to safeguard the health of individuals in the community who have dementia, to avoid the need for hospitalized care.

https://www.bidmc.org/about-bidmc/news/2020/07/preventable-hospitalizations-senior-adults-dementia

 

Researchers work to better measure delirium severity in older patients

In a study published in the journal Dementia and Geriatric Cognitive Disorders, a team of researchers led by Sarinnapha Vasunilashorn, PhD, (General Medicine, BIDMC) reported on their effort to improve and validate tools used to assess the severity of delirium. The aim was to more accurately define methods for detecting and measuring delirium symptom severity, which could in turn lead to improved prevention and treatment for patients at risk.

https://www.bidmc.org/about-bidmc/news/2020/07/delirium-severity

 

Researchers find end-of-life practices vary widely by region

Researchers including Jason H. Maley, MD, (Center for Healthcare Delivery Science, BIDMC) examined regional variation in site of death for older adults with chronic diseases from 2010 to 2016. The findings — which were published in JAMA Network Open — reveal that where chronically ill patients live may be an important determinant of whether their end-of-life care takes place in the hospital, ICU or hospice.

https://www.bidmc.org/about-bidmc/news/2020/07/end-of-life-practices-vary-by-region

 

Heat-related injuries and how to stay cool

It's important to know the signs of heat-related injuries and how to stay cool when the temperatures soar. Laura Burke, MD, (Emergency Medicine, BIDMC) shares the signs of heat exhaustion and how to protect yourself in high temperatures.

https://www.bidmc.org/about-bidmc/wellness-insights/summer-health/2019/07/heat-related-injuries-and-how-to-stay-cool

 

Screening for hepatitis C: Not just for baby boomers

Hepatitis C is a liver disease linked to more deaths in the United States than the next reportable 60 infectious diseases combined — including HIV and tuberculosis. While screening guidelines for hepatitis C previously targeted baby boomers, experts, including Camilla Graham, MD, MPH, (Infectious Diseases, BIDMC), say more universal testing guidelines should be followed for early detection and better outcomes.

https://www.bidmc.org/about-bidmc/wellness-insights/gastrointestinal-gi-health/new-universal-screening-guidelines-for-hepatitis

 

Dealing with Crohn's disease during pregnancy

Most women know it’s best to be in good physical health before getting pregnant. For women with Crohn's disease, that means more than eating right and exercising. Jacqueline Wolf, MD, (Gastroenterology, Hepatology and Nutrition, BIDMC), shares what women with Crohn’s disease, and other forms of inflammatory bowel disease, should know before getting pregnant.

https://www.bidmc.org/about-bidmc/wellness-insights/gastrointestinal-gi-health/2020/07/dealing-with-crohns-during-pregnancy

 

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CITATIONS

Nature; Journal of Gastrointestinal Surgery; mBio; Nature Medicine; Journal of General Internal Medicine; Journal of the American Geriatric Society; Dementia and Geriatric Cognitive Disorders; JAMA Network Open




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Released: 14-Aug-2020 4:55 PM EDT
Managing your child’s diabetes during COVID-19
University of Texas Health Science Center at Houston

These days it’s hard not to worry about whether a quick outing to the grocery store will result in catching COVID-19. But for parents with children who have preexisting health conditions such as diabetes, it can be especially hard not to worry about whether their child is at a higher risk of becoming severely ill from the virus.

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Released: 14-Aug-2020 3:35 PM EDT
Gaiters do no harm: WVU toxicologists find coverings help contain the spread of exhaled droplets
West Virginia University

Experts with the West Virginia University Center for Inhalation Toxicology found that – assuming it’s a good fit - a gaiter will, despite recent reports, provide a respiratory containment of exhaled droplets comparable to a common over-the-ear cloth mask.

Newswise: AI software enables real-time 3D printing quality assessment
Released: 14-Aug-2020 3:05 PM EDT
AI software enables real-time 3D printing quality assessment
Oak Ridge National Laboratory

Oak Ridge National Laboratory researchers have developed artificial intelligence software for powder bed 3D printers that assesses the quality of parts in real time, without the need for expensive characterization equipment.

Newswise: Is the COVID-19 virus pathogenic because it depletes specific host microRNAs?
Released: 14-Aug-2020 3:05 PM EDT
Is the COVID-19 virus pathogenic because it depletes specific host microRNAs?
University of Alabama at Birmingham

Why is the COVID-19 virus deadly, compared to cold-causing coronaviruses? Analysis current literature and bioinformatic study of seven coronaviruses, suggests that SARS-CoV-2 acts as a microRNA “sponge,” leading to better viral replication and blockage of the host immune response.

Released: 14-Aug-2020 2:30 PM EDT
UW team developing model to help lower COVID-19 infections in Seattle, other major cities
University of Washington

A UW team has received a grant to develop a model that uses local data to generate policy recommendations that could help lower COVID-19 infections in King County, which includes Seattle.

Newswise: Cardiovascular risk factors tied to COVID-19 complications and death
12-Aug-2020 7:05 PM EDT
Cardiovascular risk factors tied to COVID-19 complications and death
PLOS

COVID-19 patients with cardiovascular comorbidities or risk factors are more likely to develop cardiovascular complications while hospitalized, and more likely to die from COVID-19 infection, according to a new study published August 14, 2020 in the open-access journal PLOS ONE by Jolanda Sabatino of Universita degli Studi Magna Graecia di Catanzaro, Italy, and colleagues.

Newswise: Study shows frequently used serology test may not detect antibodies that could confirm protection against reinfection of COVID-19
Released: 14-Aug-2020 1:55 PM EDT
Study shows frequently used serology test may not detect antibodies that could confirm protection against reinfection of COVID-19
University of Texas M. D. Anderson Cancer Center

Two different types of detectable antibody responses in SARS-CoV-2 (COVID-19) tell very different stories and may indicate ways to enhance public health efforts against the disease, according to researchers at The University of Texas MD Anderson Cancer Center. Antibodies to the SARS-CoV-2 spike protein receptor binding domain (S-RBD) are speculated to neutralize virus infection, while the SARS-CoV-2 nucleocapsid protein (N-protein) antibody may often only indicate exposure to the virus, not protections against reinfection.

Released: 14-Aug-2020 1:50 PM EDT
USC scientists identify the order of COVID-19's symptoms
University of Southern California (USC)

USC researchers have found the likely order in which COVID-19 symptoms first appear: fever, cough, muscle pain, and then nausea, and/or vomiting, and diarrhea.

Released: 14-Aug-2020 1:45 PM EDT
Stay the Course with Personal Finances during Pandemic, Johns Hopkins Expert Advises
Johns Hopkins University Carey Business School

Keeping on a careful and steady path is the wisest approach to personal money management during the uncertainties of the COVID-19 crisis, says Associate Professor Yuval Bar-Or of the Johns Hopkins Carey Business School.

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