Research Alert

The role of ACE2 in the action of Chloroquine (CQ) and hydroxychloroquine (HCQ) needs to be further studied. Based on the existing studies, CQ/HCQ may be potential drugs for treatment of COVID-19 and other ACE2-related virus infections. However, the use of CQ/HCQ should be dealt with cautiously and careful monitoring of potential cardiotoxicity is required in clinical practice and research. The use of high doses and long-term CQ/HCQ treatment require particular care and serious consideration.

Journal Link: American Physiological Society-Function,