Fred Hutchinson Cancer Research Center

Tip Sheet: Latest research on COVID-19, health disparities, antibodies to parainfluenza, and neuron function

Summaries of recent Fred Hutch research findings and other news

Newswise — SEATTLE — May 4, 2021 — Below are summaries of recent Fred Hutch research findings and other news.

If you are covering news at the upcoming American Society of Gene & Cell Therapy, American Society of Clinical Oncology, or other conferences, feel free to reach out to our media team for help sourcing experts: [email protected].

Latest Fred Hutch research on COVID-19 In the past month, our scientists have published findings on how SARS-CoV-2 mutates and what that may mean for vaccine efficacy, how machine learning may help dampen the cytokine storm from COVID-19 and comparing immune responses from infection versus vaccination.

Event: Pathways to Equity Symposium Fred Hutch’s Office of Community Outreach and Engagement will be hosting their annual Pathways to Equity Symposium on Friday, May 2, 8:30am-12:30pm PT. Speakers will discuss racial/social justice, health equity and community engagement. Registration is free. RSVP here.

Hutch researchers discover neutralizing antibodies to parainfluenza A team of researchers led by Dr. Justin Taylor describes how they isolated five different antibodies that, in lab dish studies, potently protect against human parainfluenza virus type III, or HPIV3. Their work was published on April 20 in the open access journal mAbs.

Dr. Julie Overbaugh elected to National Academy of Sciences Virologist Dr. Julie Overbaugh, who studies factors that shape HIV transmission, was elected to the National Academy of Sciences. Overbaugh is one of 120 new members, including a record number of women, elected by their peers in recognition of their distinguished and continuing achievements in research.

Careful pruning guides neuron function Dr. Aakanksha Singhvi used tiny worms with well-mapped nervous systems in her latest work that was published in the journal eLife. She and a graduate student, Stephan Raiders, collaborated to learn how the role of accessory brain cells called glial cells support neuron function.

Seeking to expand targeted therapy for lung cancer Lung cancer researcher Dr. Alice Berger received a National Institutes of Health MERIT Award that will support her efforts to extend advances to more patients with this cancer. Berger’s MERIT Award will fund seven years of investigations into a gene that’s mutated in a subset of non-small cell lung cancer and other tumors, including some leukemias. Her ultimate goal is to extend the power of targeted therapy to more patients with lung cancer.

Event: B+T = Immunotherapy Drs. Jim Boonyaratanakornkit, Stan Riddell and Shivani Srivastava joined Dr. Bruce Clurman, Fred Hutch executive vice president and deputy director, to discuss their work studying immune cells to develop treatments for cancers and infectious diseases. Dr. Rachel Bender Ignacio also gave us an update on COVID-19 treatments happening at the Hutch’s COVID-19 Clinical Research Center. The event is part of the Hutch public science series, Science Says. Our next Science Says, on the importance of diversity and equity in science, will be June 15. Register here.

Obliteride 2021 gears up for second virtual season

Fred Hutch’s Statement on the Derek Chauvin Verdict

Essential workers illustrate the Heart of the Hutch

 

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At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first National Cancer Institute-funded cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.



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Newswise: Pandemic-Era Crowdfunding More Common, Successful in Affluent Communities
Released: 16-Jun-2021 5:05 PM EDT
Pandemic-Era Crowdfunding More Common, Successful in Affluent Communities
University of Washington

A new University of Washington study of requests and donations to the popular crowdfunding site GoFundMe, along with Census data, shows stark inequities in where the money went and how much was donated.

Newswise: In Show of COVID-19 Vaccine Confidence, 96% of America’s Ophthalmologists Already Vaccinated
Released: 16-Jun-2021 3:50 PM EDT
In Show of COVID-19 Vaccine Confidence, 96% of America’s Ophthalmologists Already Vaccinated
American Academy of Ophthalmology (AAO)

The American Academy of Ophthalmology is calling on its members to continue to build confidence in COVID-19 vaccines and encourage people to get vaccinated, including their staff.

Newswise: Biophysical Study Sheds Light on Potentially Druggable Process of SARS-CoV-2 Replication
Released: 16-Jun-2021 12:50 PM EDT
Biophysical Study Sheds Light on Potentially Druggable Process of SARS-CoV-2 Replication
National Institute of Biomedical Imaging and Bioengineering

This study investigates how the nucleocapsid protein, or N protein, of the SARS-CoV-2 virus packages the viral genome.

Newswise: ‘Wonder material’ can be used to detect COVID-19 quickly, accurately
Released: 16-Jun-2021 11:55 AM EDT
‘Wonder material’ can be used to detect COVID-19 quickly, accurately
University of Illinois at Chicago

Researchers at the University of Illinois Chicago have successfully used graphene — one of the strongest, thinnest known materials — to detect the SARS-CoV-2 virus in laboratory experiments.

Newswise: UCLA-led Research Finds Connections Between Air Quality and COVID Vulnerability
Released: 16-Jun-2021 11:05 AM EDT
UCLA-led Research Finds Connections Between Air Quality and COVID Vulnerability
UCLA Fielding School of Public Health

Even as governments across the United States consider lifting mask mandates and relaxing preventative measures as vaccination numbers creep up, new research from a UCLA-led team has found that such basic techniques significantly reduce the risk of getting COVID-19. In addition, the research found that U.S. counties with higher exposures to poor air quality, historically, saw higher county-level COVID-19 mortality rates in 2020.

Newswise: Story Tips from Johns Hopkins Experts on COVID-19
Released: 16-Jun-2021 11:00 AM EDT
Story Tips from Johns Hopkins Experts on COVID-19
Johns Hopkins Medicine

NEWS STORIES IN THIS ISSUE: - Stressed About “Returning to Normal”? Here Are Tips to Ease Into the Transition - Be Your Brother’s Keeper: Steps for Faith-Based Communities to Reopen Safely

Newswise: Virtual Event For June 17, 11AM EDT: COVID-19 Vaccines and Male Fertility
Released: 16-Jun-2021 8:55 AM EDT
Virtual Event For June 17, 11AM EDT: COVID-19 Vaccines and Male Fertility
Newswise

This upcoming JAMA-published study examined whether the COVID-19 vaccine impacts male fertility.

Released: 16-Jun-2021 8:00 AM EDT
Two COVID-19 Vaccines Show Safety, Strong Immunity in Infant Model
University of North Carolina School of Medicine

The Moderna mRNA vaccine and a protein-based vaccine candidate elicited durable neutralizing antibody responses to SARS-CoV-2 in pre-clinical research. There were no adverse effects.

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Embargo will expire: 17-Jun-2021 5:00 AM EDT Released to reporters: 16-Jun-2021 5:00 AM EDT

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