Fred Hutchinson Cancer Research Center

Tip Sheet: Latest research on COVID-19, health disparities, antibodies to parainfluenza, and neuron function

Summaries of recent Fred Hutch research findings and other news

Newswise — SEATTLE — May 4, 2021 — Below are summaries of recent Fred Hutch research findings and other news.

If you are covering news at the upcoming American Society of Gene & Cell Therapy, American Society of Clinical Oncology, or other conferences, feel free to reach out to our media team for help sourcing experts: [email protected].

Latest Fred Hutch research on COVID-19 In the past month, our scientists have published findings on how SARS-CoV-2 mutates and what that may mean for vaccine efficacy, how machine learning may help dampen the cytokine storm from COVID-19 and comparing immune responses from infection versus vaccination.

Event: Pathways to Equity Symposium Fred Hutch’s Office of Community Outreach and Engagement will be hosting their annual Pathways to Equity Symposium on Friday, May 2, 8:30am-12:30pm PT. Speakers will discuss racial/social justice, health equity and community engagement. Registration is free. RSVP here.

Hutch researchers discover neutralizing antibodies to parainfluenza A team of researchers led by Dr. Justin Taylor describes how they isolated five different antibodies that, in lab dish studies, potently protect against human parainfluenza virus type III, or HPIV3. Their work was published on April 20 in the open access journal mAbs.

Dr. Julie Overbaugh elected to National Academy of Sciences Virologist Dr. Julie Overbaugh, who studies factors that shape HIV transmission, was elected to the National Academy of Sciences. Overbaugh is one of 120 new members, including a record number of women, elected by their peers in recognition of their distinguished and continuing achievements in research.

Careful pruning guides neuron function Dr. Aakanksha Singhvi used tiny worms with well-mapped nervous systems in her latest work that was published in the journal eLife. She and a graduate student, Stephan Raiders, collaborated to learn how the role of accessory brain cells called glial cells support neuron function.

Seeking to expand targeted therapy for lung cancer Lung cancer researcher Dr. Alice Berger received a National Institutes of Health MERIT Award that will support her efforts to extend advances to more patients with this cancer. Berger’s MERIT Award will fund seven years of investigations into a gene that’s mutated in a subset of non-small cell lung cancer and other tumors, including some leukemias. Her ultimate goal is to extend the power of targeted therapy to more patients with lung cancer.

Event: B+T = Immunotherapy Drs. Jim Boonyaratanakornkit, Stan Riddell and Shivani Srivastava joined Dr. Bruce Clurman, Fred Hutch executive vice president and deputy director, to discuss their work studying immune cells to develop treatments for cancers and infectious diseases. Dr. Rachel Bender Ignacio also gave us an update on COVID-19 treatments happening at the Hutch’s COVID-19 Clinical Research Center. The event is part of the Hutch public science series, Science Says. Our next Science Says, on the importance of diversity and equity in science, will be June 15. Register here.

Obliteride 2021 gears up for second virtual season

Fred Hutch’s Statement on the Derek Chauvin Verdict

Essential workers illustrate the Heart of the Hutch

 

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At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first National Cancer Institute-funded cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.



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Embargo will expire: 21-Jun-2021 11:00 AM EDT Released to reporters: 17-Jun-2021 12:10 PM EDT

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Newswise: Blood Cancer Patients with COVID-19 Fare Better with Convalescent Plasma
Released: 17-Jun-2021 11:55 AM EDT
Blood Cancer Patients with COVID-19 Fare Better with Convalescent Plasma
Washington University in St. Louis

A large, retrospective, multicenter study involving Washington University School of Medicine in St. Louis indicates that convalescent plasma from recovered COVID-19 patients can dramatically improve likelihood of survival among blood cancer patients hospitalized with the virus. The therapy involves transfusing plasma — the pale yellow liquid in blood that is rich in antibodies — from people who have recovered from COVID-19 into patients who have leukemia, lymphoma or other blood cancers and are hospitalized with the viral infection.

Released: 17-Jun-2021 11:05 AM EDT
Stress during pandemic linked to poor sleep
Washington State University

Many people likely lost sleep over COVID-19. A study of twins led by Washington State University researchers found that stress, anxiety and depression during the first few weeks of the pandemic were associated with less and lower quality sleep.

Newswise:Video Embedded university-of-miami-miller-school-study-shows-covid-19-mrna-vaccines-do-not-impact-male-fertility
VIDEO
Released: 17-Jun-2021 11:00 AM EDT
University of Miami Miller School Study Shows COVID-19 mRNA Vaccines Do Not Impact Male Fertility
University of Miami Health System, Miller School of Medicine

The Pfizer and Moderna mRNA COVID-19 vaccines is safe for male reproduction, according to a new study by University of Miami Miller School of Medicine researchers published in JAMA , the most widely circulated general medical journal in the world.

15-Jun-2021 1:20 PM EDT
Higher COVID-19 Mortality Among Black Patients Linked to Unequal Hospital Quality
Perelman School of Medicine at the University of Pennsylvania

If Black patients were admitted to the same hospitals that serve a majority of White patients, researchers showed their risk of death would drop by 10 percent

Released: 17-Jun-2021 9:35 AM EDT
Hackensack Meridian CDI Scientists Develop ‘CATCHER’ for Crucial Biomarkers
Hackensack Meridian Health

The EV-CATCHER methodology identifies and captures tiny pieces of genetic material – and shows value in COVID-19 plasma

Newswise: “ChulaCov19” Thailand’s First COVID-19 Vaccine Has Been Tested on Humans
Released: 17-Jun-2021 8:55 AM EDT
“ChulaCov19” Thailand’s First COVID-19 Vaccine Has Been Tested on Humans
Chulalongkorn University

On June 14, 2021 at Bhumisirimangalanusorn Building, Chulalongkorn Memorial Hospital, the Thai Red Cross Society, the Faculty of Medicine and the Chula Vaccine Research Center (CVRC), Faculty of Medicine, Chulalongkorn University conducted its first phase of clinical trial on volunteers who have passed the screening process and deemed to be in good health. The process is continuing on to phase 2 to monitor immunity reactions to the ChulaCov19 vaccine under the supervision of medical experts, doctors, nurses and the research team.

16-Jun-2021 5:00 AM EDT
Disadvantaged Neighborhoods See More COVID-19 Infections and Deaths, Mount Sinai Scientists Report
Mount Sinai Health System

New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.

Newswise: Pandemic-Era Crowdfunding More Common, Successful in Affluent Communities
Released: 16-Jun-2021 5:05 PM EDT
Pandemic-Era Crowdfunding More Common, Successful in Affluent Communities
University of Washington

A new University of Washington study of requests and donations to the popular crowdfunding site GoFundMe, along with Census data, shows stark inequities in where the money went and how much was donated.

Newswise: In Show of COVID-19 Vaccine Confidence, 96% of America’s Ophthalmologists Already Vaccinated
Released: 16-Jun-2021 3:50 PM EDT
In Show of COVID-19 Vaccine Confidence, 96% of America’s Ophthalmologists Already Vaccinated
American Academy of Ophthalmology (AAO)

The American Academy of Ophthalmology is calling on its members to continue to build confidence in COVID-19 vaccines and encourage people to get vaccinated, including their staff.


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