Viewing COVID-19 through the lens of data science

22-May-2020 3:20 PM EDT, by MIT Press

Newswise — Multidisciplinary study of the COVID-19 pandemic and its wide-ranging impact has become an urgent endeavor worldwide. To further and deepen global understanding of the crisis, the Harvard Data Science Review (an open access platform of the Harvard Data Science Initiative) is publishing a special issue examining the novel coronavirus and its impact through the lens of data science.

The issue covers a wide range of topics addressing the societal, epidemiological, political, and educational issues that have rapidly emerged from the SARS-CoV2 pandemic. Articles include:

  • A Conversation About Covid-19 With Biostatisticians and Epidemiologists
    David Banks (Duke University), Susan Ellenberg (University of Pennsylvania), Thomas Fleming (University of Washington), M. Elizabeth Halloran (University of Washington), Andrew Lawson (Medical University of South Carolina), and Lance Waller (Emory University)

    Five leading biostatisticians and epidemiologists debate the probable scope and duration of the pandemic, the kinds of medical responses that we need, and some of the impacts they foresee on the U.S. and on the world. They also discuss the pandemic's likely effect on higher education.
  • The Coronavirus Exponential: A Preliminary Investigation into the Public's Understanding
    Alexander Podkul (Optimus), Scott Tranter (Optimus), Liberty Vittert (Washington University, St. Louis), Alex Alduncin (Optimus)

    The reasons why we are currently "socially distancing" are based on an understanding of exponential growth and the idea of "flattening the curve." The authors present and discuss a pair of survey experiments that explore the public's statistical literacy by examining its ability to calculate and understand exponential growth. These findings may be used to help better ground effective communication strategies aimed at the general public.

  • Bayesian Adaptive Clinical Trials for Anti-Infective Therapeutics During Epidemic Outbreaks
    Shomesh Chaudhuri (QLS Advisors), Andrew W. Lo (MIT), Danying Xiao (MIT), and Qingyang Xu (MIT)

    In the midst of the COVID-19 pandemic, how should regulatory agencies adapt their normally lengthy clinical trial and approval process to address the urgency of finding treatments and saving lives? The authors propose a Bayesian adaptive patient-centered framework to optimize the clinical trial development path for anti-infective therapies and vaccines. Their research provides a rational, systematic, transparent, repeatable, and practical framework for regulators, policymakers, and clinical researchers to evaluate the efficacy of anti-infective therapeutics during the course of any epidemic outbreak when the cost of false negatives far outweighs the cost of false positives.

  • Estimating Probabilities of Success of Vaccine and Other Anti-Infective Therapeutic Development Programs
    Andrew W. Lo (MIT), Kien Wei Siah (MIT), Chi Heem Wong (MIT)

    The economic value of a drug or medical device development program is typically computed by assessing the program's cumulative revenues if successful, and companies rely on this data to make business decisions about which programs to pursue and how to fund them.

    In this article, the authors provide estimates of clinical trial outcomes for vaccines and other anti-infective therapeutics using 43,414 unique triplets of clinical trial, drug, and disease between January 1, 2000, and January 7, 2020, yielding 2,544 vaccine programs and 6,829 non-vaccine programs targeting infectious diseases--the largest dataset of its kind. As governments around the world begin to formulate a more systematic strategy for dealing with pandemics beyond COVID-19, these estimates can be used by policymakers to identify areas most likely to be undeserved by private-sector engagement and in need of public-sector support.

  • Tackling Covid-19 through Responsible AI Innovation: Five Steps in the Right Direction
    David Leslie (The Alan Turing Institute)

    Innovations in data science and artificial intelligence (AI) have a central role to play in supporting global efforts to combat COVID-19 and address a broad range of biomedical, epidemiological, and socio-economic challenges. However, this wide-reaching scientific capacity also raises ethical challenges.

    The authors present a practice-based path to responsible AI design and discovery centered on open, accountable, equitable, and democratically governed processes and products. When taken from the start, these steps will not only enhance the capacity of innovators to tackle Covid-19 responsibly, they will help to set the data science and AI community down a path that is both better prepared to cope with future pandemics and better equipped to support a more humane, rational, and just society of tomorrow.

The special issue will be published on a rolling/continuous basis with new articles appearing weekly through the beginning of July 2020.

SEE ORIGINAL STUDY




Filters close

Showing results

110 of 2057
Newswise: Pulmonary Embolism and COVID-19
Released: 2-Jun-2020 3:10 PM EDT
Pulmonary Embolism and COVID-19
Henry Ford Health System

Researchers at Henry Ford Health System in Detroit say early diagnosis of a life-threatening blood clot in the lungs led to swifter treatment intervention in COVID-19 patients. In a new study published recently in the journal Radiology, researchers found that 51 percent of patients found to have a pulmonary embolism, or PE, were diagnosed in the Emergency Department, the entry point for patients being admitted to the hospital.

Newswise: Notre Dame researchers to create material for new antimicrobial mask
Released: 2-Jun-2020 2:55 PM EDT
Notre Dame researchers to create material for new antimicrobial mask
University of Notre Dame

Scientists and engineers are collaborating to translate existing water filtration technology to create a new fabric that will not only capture viruses, like the coronavirus, but also deactivate them.

access_time Embargo lifts in 2 days
Embargo will expire: 4-Jun-2020 9:00 AM EDT Released to reporters: 2-Jun-2020 2:40 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 4-Jun-2020 9:00 AM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 2-Jun-2020 1:55 PM EDT
Research Affiliates CEO on Leading and Investing in a Time of Uncertainty
University of Virginia Darden School of Business

As CEO of global asset management firm Research Affiliates, Katrina Sherrerd (Ph.D. ’87) is leading the influential financial services firm through a period of deep global uncertainty, as world financial markets continue to show great volatility amid the coronavirus pandemic.

Newswise: Studying pandemic's effects on sexual health and well-being
Released: 2-Jun-2020 1:50 PM EDT
Studying pandemic's effects on sexual health and well-being
Indiana University

One in five adults in the United States report they have experienced change – mostly a decrease – in their sexual behavior during the early months of the COVID-19 pandemic, according to a new study by Indiana University researchers.

Newswise: HarrisJared-fac-profile.jpg?itok=pQ8OjWkt
Released: 2-Jun-2020 1:50 PM EDT
Keys to Small Business Resilience in Uncertain Times
University of Virginia Darden School of Business

Faced with limited customer flow, forced shut down of operations and a looming economic recession, the uncertainty of the COVID-19 pandemic leaves small-business owners to make decisions with little idea of what the future may hold. What lessons can they take from the success and resiliency of businesses that have survived crises in the past?

Released: 2-Jun-2020 1:05 PM EDT
Suppression of COVID-19 spread is possible, suggests new model
Washington University in St. Louis

Suppression of the spread of COVID-19 is an attainable goal, and it can be done through strategies that ease social distancing guidelines, suggests a new model developed by researchers at Washington University in St. Louis and the Brookings Institution.

Newswise: COVID-19 Pandemic Highlights Advantages of Digital Technology in Clinical Research
Released: 2-Jun-2020 11:05 AM EDT
COVID-19 Pandemic Highlights Advantages of Digital Technology in Clinical Research
Osteopathic Research Center, University of North Texas Health Science Center

Digital technology has facilitated continued research operations for a pain research registry during the COVID-19 pandemic. Cloud-based systems that allow remote management of research studies and collection of data may signal a new trend for future clinical research endeavors.

Released: 2-Jun-2020 10:25 AM EDT
Pediatric injuries in the home are on the rise
University of Texas Health Science Center at Houston

COVID-19 has changed the way families go about their daily routines. With public schools being closed, most parents now have to take on several roles at once. Most are working, providing home schooling and care during the day, and taking on other new roles.


Showing results

110 of 2057

close
1.72414