Stanford Cancer Team Halts Growth of Multiple Myeloma and Diffuse Large B Cell Lymphoma in Mice with Custom Molecule sBCMA-Fc V3

Researchers at Stanford University have developed “decoy receptor” molecules that inhibit the growth of both multiple myeloma (MM) and diffuse large B cell lymphoma (DLBCL) in mice. The molecules, described in a study to be published July 26 in...
20-Jul-2022 10:35 AM EDT Add to Favorites

Broadly neutralizing antibodies could provide immunity against SARS-CoV-2 variants

Two broadly neutralizing antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations according to a paper published June 15 in the Journal of Experimental Medicine (JEM). The antibodies were...
15-Jun-2022 2:20 PM EDT Add to Favorites

Discovery of an 'Eat-Me' signal involved in synaptic pruning and maturation of new neurons in the adult brain

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Chihiro Kurematsu, a student at Nagoya City University School of Medicine, has elucidated the mechanism that...
15-Mar-2022 3:05 PM EDT Add to Favorites

Cancer cell's iron addiction may enable specific drug targeting, study suggests

Researchers at the University of California, San Francisco (UCSF), have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this “ferroaddiction” can be exploited to...
3-Mar-2022 10:30 AM EST Add to Favorites

Cancer drug shows promise in treating infants with rare disease that causes tissue overgrowth

PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body. A new report to be published January 26 in the...
19-Jan-2022 11:05 AM EST Add to Favorites

Fast-tracked stroke drug for humans shows promise, in mice, that it might also prove a powerful tool against dementia

USC study published in the Journal of Experimental Medicine shows that experimental drug protects against injury caused by tiny blood clots in the brain’s white matter, which can accumulate over time and lead to cognitive decline
1-Dec-2021 10:25 AM EST Add to Favorites

Open access content from Rockefeller University Press now available on ResearchGate

ResearchGate and Rockefeller University Press (RUP) today announced the completion of the first phase of a content syndication pilot partnership. ResearchGate users can now find full-text Immediate OA articles and a subset of five years of archival...
23-Nov-2021 11:00 AM EST Add to Favorites

By putting cancer cells to sleep, new drug could prevent tumor metastasis

A new therapeutic approach prevents the growth of metastatic tumors in mice by forcing cancer cells into a dormant state in which they are unable to proliferate. The study, published November 23 in the Journal of Experimental Medicine (JEM), could...
23-Nov-2021 10:00 AM EST Add to Favorites