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Potential Targeted Treatment for Acute Myeloid Leukemia Identified

Scientists from Sanford Burnham Prebys have shown that a protein called BMI1 is a promising drug target for an AML subtype in which two normally separate genes, CALM and AF10, fuse together. The findings, published in Experimental Hematology,...
15-May-2019 8:00 AM EDT Add to Favorites


Conquering Cancer’s Infamous KRAS Mutation

Scientists from Sanford Burnham Prebys and PHusis Therapeutics have shown that a compound called PHT-7.3 shrinks KRAS-driven tumors in mice. In contrast to directly targeting mutant KRAS, the potential drug candidate targets the protein’s partner...
14-May-2019 8:00 AM EDT Add to Favorites


Boosting Muscle Stem Cells to Treat Muscular Dystrophy and Aging Muscles

Scientists from Sanford Burnham Prebys have uncovered a molecular signaling pathway involving Stat3 and Fam3a proteins that regulates how muscle stem cells decide whether to self-renew or differentiate—an insight that could lead to muscle-boosting...
16-Apr-2019 12:05 PM EDT Add to Favorites


New Metascape platform enables biologists to unlock big-data insights

Scientists from Sanford Burnham Prebys and the Genomics Institute of the Novartis Research Foundation have revealed an open-access, web-based portal that integrates more than 40 advanced bioinformatics data sources to allow non-technical users to...
3-Apr-2019 12:05 PM EDT Add to Favorites


Gut Microbiome Directs the Immune System to Fight Cancer

A study from Sanford Burnham Prebys has demonstrated a causal link between the gut microbiome and the immune system’s ability to fight cancer. The researchers identified a cocktail of 11 bacterial strains that activated the immune system and...
28-Mar-2019 1:05 PM EDT Add to Favorites


Helping Infants Survive Brain Cancer

Choroid plexus carcinoma (CPC) is a particularly challenging type of brain cancer. The tumor most commonly arises in infants under the age of one—who are too young to undergo radiation treatment. Only 40 percent of children remain alive five years...
27-Mar-2019 8:00 AM EDT Add to Favorites

WARF Therapeutics Announces Partnership with Sanford Burnham Prebys Medical Discovery Institute

As part of its strategic initiative to bring new pharmaceuticals closer to patients, WARF Therapeutics announces a new partnership with Sanford Burnham Prebys Medical Discovery Institute (SBP). Under the terms of the 5-year agreement, WARF and...
21-Mar-2019 1:00 PM EDT Add to Favorites


Sanford Burnham Prebys Medical Discovery Institute welcomes new trustees

Sanford Burnham Prebys Medical Discovery Institute (SBP) today announced that Matt Browne, a partner in Cooley LLP’s San Diego office; and David L. Szekeres, senior vice president, Business Development, and general counsel for Heron Therapeutics,...
7-Mar-2019 8:00 AM EST Add to Favorites

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Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at or on Facebook at and on Twitter @SBPdiscovery.


  • Jerold Chun

    Professor & Senior VP- Neuroscience Drug Discovery

    Neuroscience, Alzheimer's Disease, Multiple Sclerosis (MS), Parkinson's Disease
  • Evan Snyder

    Professor & Director - Stem Cell Regenerative Med.

    Stem Cells, Spinal Cord Injury, Parkinson's Disease, ALS, Bipolar Disorder


Monica May
Science Writer


Deborah Robison
Vice President, Communications


Karli Schwab
Communications Coordinator


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