Scientists from Sanford Burnham Prebys have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry. The findings...
25-Jun-2019 2:00 PM EDT Add to Favorites
Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging “fuel” through an alternative supply route, called macropinocytosis. Blocking this process, often described as “cellular drinking,” could lead to tumor-starving...
20-Jun-2019 4:55 PM EDT Add to Favorites
New research on amyotrophic lateral sclerosis (AML) has revealed that a protein called membralin plays a key role in the disease process. The study, published in Journal of Clinical Investigation, suggests that membralin-boosting gene therapy is a...
23-May-2019 5:05 PM EDT Add to Favorites
Scientists from Sanford Burnham Prebys have shown that a protein called BMI1 is a promising drug target for an AML subtype in which two normally separate genes, CALM and AF10, fuse together. The findings, published in Experimental Hematology,...
15-May-2019 8:00 AM EDT Add to Favorites
Scientists from Sanford Burnham Prebys and PHusis Therapeutics have shown that a compound called PHT-7.3 shrinks KRAS-driven tumors in mice. In contrast to directly targeting mutant KRAS, the potential drug candidate targets the protein’s partner...
14-May-2019 8:00 AM EDT Add to Favorites
Scientists from Sanford Burnham Prebys have uncovered a molecular signaling pathway involving Stat3 and Fam3a proteins that regulates how muscle stem cells decide whether to self-renew or differentiate—an insight that could lead to muscle-boosting...
16-Apr-2019 12:05 PM EDT Add to Favorites
Scientists from Sanford Burnham Prebys and the Genomics Institute of the Novartis Research Foundation have revealed an open-access, web-based portal that integrates more than 40 advanced bioinformatics data sources to allow non-technical users to...
3-Apr-2019 12:05 PM EDT Add to Favorites
A study from Sanford Burnham Prebys has demonstrated a causal link between the gut microbiome and the immune system’s ability to fight cancer. The researchers identified a cocktail of 11 bacterial strains that activated the immune system and...
28-Mar-2019 1:05 PM EDT Add to Favorites
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