Released: 1-May-1998 12:00 AM EDT
Children With Asthma Have SNO Deficiency
University of Virginia Health System

CHARLOTTESVILLE, Va.-- Researchers at the University of Virginia Health Sciences Center and Howard Hughes Medical Institute, Duke University Medical Center have found that a deficiency of S-nitrosothiol (SNO), a chemical that dilates the bronchial tubes, is associated with severe asthma in children. The finding, published in the May 2 issue of Lancet, may help doctors develop new asthma therapies aimed at correcting this deficiency.

Released: 9-May-1998 12:00 AM EDT
Gene Therapy Shows Promise in Protecting Hearts during Surgery
University of Virginia Health System

During heart surgery, an estimated 5 percent of patients suffer damage to the heart muscle when blood flow is briefly cout off. But researchers at the University of Virginia have found that a method of gene therapy used in mice significantly protects the heart during periods of low blood flow.

Released: 16-Jun-1998 12:00 AM EDT
Mild Hypoglycemia Impairs Driving in People with Type I Diabetes
University of Virginia Health System

For people with Type I diabetes, episodes of even mild hypoglycemia can make driving dangerous, according to researchers at the University of Virginia Health Sciences Center.

Released: 20-Jun-1998 12:00 AM EDT
Computer-Guided Approach for Repair of Pelvic Fractures
University of Virginia Health System

A surgeon from the University of Virginia Health Sciences Center has developed a computer-guided surgical technique for pelvic and hip socket fractures that is more accurate and less invasive than traditional surgery and dramatically reduces the patient's length of stay in the hospital.

Released: 30-Jun-2000 12:00 AM EDT
Mitochondrial Function Defects and Alzheimer's Disease
University of Virginia Health System

Medical researchers at the University of Virginia Health System have succeeded in directly linking the brain cell damage and death that are hallmarks of Alzheimer's disease to abnormalities in mitochondrial genes (Annals of Neurology, 7-00).

Released: 9-Sep-2000 12:00 AM EDT
UVA School of Medicine Receives $20 Million
University of Virginia Health System

The University of Virginia School of Medicine has received $20 million for prostate cancer research from the estate of the late Paul Mellon.

2-Nov-2000 12:00 AM EST
Spread of Flu in Families Reduced with Zanamivir
University of Virginia Health System

A new study found that zanamivir can prevent the flu from making the rounds within a family when one member becomes infected. (The New England Journal of Medicine, 11-2-00)

2-Jan-2001 12:00 AM EST
Method to Detect Infection Earlier in Newborns
University of Virginia Health System

Medical researchers at the University of Virginia Health System have developed a method that may alert physicians to early stages of severe infection in newborn infants. (Pediatrics, 12-00)

Released: 1-Feb-2001 12:00 AM EST
Gene Identified That Could Lead to Better Diagnosis and Treatment of Cancer
University of Virginia Health System

Researchers at the University of Virginia Health System have identified a new gene, SPAN-X, that could eventually lead to better diagnosis and treatment for certain cancers. (Biology of Reproduction, 02-01)

24-Feb-2001 12:00 AM EST
Study on Magnet Therapy Shows Limited Potential for Pain Relief
University of Virginia Health System

University of Virginia researchers published results from one of the first clinical research studies conducted on magnet therapy for pain. (J. of Alternative and Complementary Medicine, 2-22-01)

Released: 13-Mar-2001 12:00 AM EST
Childhood Exposure to Cats Reduces Asthma Risk
University of Virginia Health System

Children exposed to domestic cats have a decreased risk for developing asthma according to a new study from the University of Virginia Health System. (Lancet, 3-01)

Released: 4-May-2001 12:00 AM EDT
Sexual Dysfunction Results from Anti-depressant Drugs
University of Virginia Health System

All but two of the newer anti-depressant drugs cause significant sexual dysfunction, according to results of a study conducted by the associate professor and vice chairman, Department of Psychiatric Medicine, University Virginia Health System and a primary care physician in New Baltimore, Mich.

5-Jun-2001 12:00 AM EDT
Lower Hormone Replacement Therapy Just as Effective
University of Virginia Health System

Lower doses of hormone replacement therapy are just as effective at reducing hot flashes and vaginal changes in postmenopausal women as currently prescribed doses, according to a University of Virginia, HSC study.

14-Jun-2001 12:00 AM EDT
New Way to Detect Residual Bladder Cancer in Lymph Nodes
University of Virginia Health System

A highly sensitive method for detecting residual bladder cancer present in a patient's lymph node at the time of surgery has been discovered through a study conducted at the University of Virginia Health System and the University of Western Ontario.

Released: 14-Jun-2001 12:00 AM EDT
Grant for Further Development of Lung Imaging Procedure
University of Virginia Health System

Finding an improved imaging technique to detect lung diseases at an earlier stage when treatment is more likely to be effective, is emerging through leading research by University of Virginia Health System professors.

23-Jun-2001 12:00 AM EDT
Too Much Blood Sugar Slows Brain Function in Type 1 Diabetes Patients
University of Virginia Health System

A new study by U.Va. researchers shows that insulin-dependent (type 1) diabetes patients experience slower brain function and other short-term symptoms from too much blood sugar, or hyperglycemia.

10-Aug-2001 12:00 AM EDT
Evidence of Second Genetic Code
University of Virginia Health System

Sequencing and mapping the human genome was the first essential step for scientists to study where genes for diseases like cancer are located. But in studies to identify the complex factors that make those genes active or inactive, molecular genetic researchers at the University of Virginia have discovered a new area outside the DNA itself that may show existence of another type of genetic code.

Released: 6-May-2004 3:50 PM EDT
Disruption of Gene May Prevent Type 1 Diabetes
University of Virginia Health System

Disrupting a gene called Stat-4 suppresses the activation of white blood cells involved in the development of type 1 diabetes, say researchers.

Released: 12-May-2004 6:10 AM EDT
Treatment May Reduce Death from Sepsis
University of Virginia Health System

An experimental therapy that combines an antibiotic with a synthetic anti-inflammatory drug, designed at the University of Virginia Health System, has shown early promise in dramatically reducing death from sepsis, a life-threatening infection that kills 210,000 Americans each year.

Released: 25-May-2004 2:40 PM EDT
Good News for Red Wine Drinkers: Protein in Grape Skins Can Kill Cancer Cells
University of Virginia Health System

It's well known that drinking red wine in moderation can have some health benefits, mainly attributed to a compound called resveratrol. Now, scientists have discovered how. They found how resveratrol helps to starve cancer cells by inhibiting the action of a key protein that feeds them.

Released: 14-Jun-2004 2:30 PM EDT
Major Diabetes Procedure: First Islet Cell Transplant in Virginia
University of Virginia Health System

A Charlottesville area woman may no longer need the insulin shots she's been giving herself every day for 32 years. Lori Ratliff of Ivy became Virginia's first recipient of an islet cell transplant.

Released: 14-Jan-2005 12:30 PM EST
Blocking a Certain Protein Could Cause Regeneration of Inner Ear Hair Cells
University of Virginia Health System

Researchers at the University of Virginia Health System, Massachusetts General Hospital and Harvard Medical School have discovered a new molecular target for future research on regenerating and replacing inner ear hair cells.

Released: 14-Jan-2005 12:40 PM EST
Scientists Crack Part of "Histone" Code
University of Virginia Health System

Researchers at the University of Virginia Health System have unraveled one mystery about what histones accomplish in the complex chemical cascade that determines the function of a cell in the body.

Released: 1-Feb-2005 11:00 AM EST
Chief of Cardiology Has Resolutions for a Heart-Healthy Year
University of Virginia Health System

The new Chief of Cardiology at the University of Virginia Health System and Co-Director of the U. Va. Heart and Vascular Center, effective Jan. 1, recommends the following resolutions for every adult to keep their heart disease-free in the New Year and beyond.

31-Jan-2005 5:00 PM EST
Compound from Rare Plant Shows Promise in Breast Cancer Treatment
University of Virginia Health System

After five years of sophisticated tests, scientists at the University of Virginia Health System have discovered that a compound, derived from a rare South American plant, stops the growth of human breast cancer cells in laboratory cultures.

Released: 24-Feb-2005 12:00 PM EST
Genome of Deadly Pathogen Sequenced
University of Virginia Health System

Researchers have succeeded in sequencing the genome of a parasitic amoeba called Entamoeba histolytica. The amoeba infects about 50 million people around the world with a disease called amebiasis, causing up to 100,000 deaths a year, usually in developing countries with poor sanitary conditions.

Released: 11-Mar-2005 12:00 PM EST
Role for Estrogen Receptor in Behavioral Sex Differences
University of Virginia Health System

What makes a man behave like a man and a woman a woman? The answer may be partly in your genes. Researchers at the University of Virginia Health System have discovered a new twist on the role that estrogens play in the development of behavioral differences between males and females.

Released: 28-Mar-2005 12:00 PM EST
Patient Receives First FDA-Approved Graft for Thoracic Aortic Aneurysms
University of Virginia Health System

In a two-hour procedure, a 72-year-old retired mail carrier from Etowah, North Carolina became the first person in the United States to be implanted with a new, high-tech graft just approved by the U. S. Food and Drug Administration to treat potentially-deadly aneurysms in the thoracic aorta without open surgery.

Released: 28-Jun-2005 2:20 PM EDT
AMA Recognizes UVa Health System’s Patient Communication Programs
University of Virginia Health System

The University of Virginia Health System is one of eight hospitals in the United States winning recognition from The American Medical Association for developing exemplary programs to improve communication between health care professionals and patients.

Released: 29-Jun-2005 12:00 PM EDT
Drug to Treat Deadly Complication of Stroke Tested in Clinical Trial
University of Virginia Health System

A Roanoke, Va. woman is the first U. S. participant in an international, multi center trial of a new drug that shows promise in treating complications from a stroke.

Released: 5-Aug-2005 11:00 AM EDT
West Virginia Great-Grandmother Is Patient Five Thousand for Gamma Knife
University of Virginia Health System

The Lars Leksell Gamma Knife center at the University of Virginia Health System set a milestone on August 1, when 75-year-old Macel Morris of Charleston, W. Va., became the 5,000th patient to undergo Gamma Knife treatment at UVa's University Hospital.

Released: 2-Sep-2005 1:25 PM EDT
Adult Stem Cells from Adipose Tissue Could Save Lives
University of Virginia Health System

National and international scientists, including those from the University of Virginia Health System, will announce findings from a significant number of studies showing that adult stem cells from adipose tissue (fat) could eventually be used to treat injured or damaged tissues.

Released: 19-Sep-2005 4:10 PM EDT
UVa Participates in Landmark Breast Cancer Screening Trial
University of Virginia Health System

Digital mammography that uses computers to detect breast cancer found significantly more cancers than screen film mammography in women 50 and younger, premenopausal and perimenopausal women, and women with dense breasts, according to results from one of the largest breast cancer screening studies ever performed.

Released: 21-Sep-2005 5:00 PM EDT
New Type of Nerve Cell That Could Be Target for Drugs to Ease Pain
University of Virginia Health System

Experts say up to two percent of the U.S. population suffers from neuropathic pain. But this pain generally responds poorly to analgesics and other standard treatment and get worse over time, causing permanent disability in some people. Now there may be new hope for these pain sufferers.

Released: 24-Oct-2005 2:35 PM EDT
Dr. Jonathan Moreno Elected to Prestigious Institute of Medicine
University of Virginia Health System

Jonathan Moreno, PhD, Emily Davie and Joseph S. Kornfeld Professor of Biomedical Ethics and Director of the Center for Biomedical Ethics at the University of Virginia Health System, has been elected to membership in the Institute of Medicine of the National Academies.

Released: 26-Oct-2005 4:00 PM EDT
A Natural Carbohydrate Can Help Lower Blood Sugar
University of Virginia Health System

A carbohydrate isolated from the liver lowers blood sugar levels after it is injected into diabetic rats, according to research carried out by a team of experts at the University of Virginia Health System.

Released: 2-Nov-2005 4:00 PM EST
UVa Medical Center Named One of Top 100 Cardiovascular Hospitals
University of Virginia Health System

For the third year in a row, the University of Virginia cardiology and heart surgery program has been chosen as one of the top 100 in the nation by the healthcare consulting company, Solucient, LLC.

Released: 13-Dec-2005 2:15 PM EST
UVa Health System Opens Clinical Trial of Emphysema Treatment
University of Virginia Health System

Doctors have opened a new clinical trial to try and help people with emphysema breathe better. The study will test the safety and effectiveness of a bronchoscopic valve, an experimental device designed to channel air to healthier portions of the lung.

Released: 3-Jan-2006 1:45 PM EST
Doctors Search for New Treatments for Diabetic Kidney Disease
University of Virginia Health System

Dr. Mark Okusa, a nephrologist and professor of medicine at the University of Virginia Health System, has won two grants totaling $1.2 million over four years to test whether certain drugs can interrupt the inflammatory process that occurs in diabetic kidney disease.

Released: 10-Jan-2006 5:00 PM EST
St. Johns Wort & Prescription Medicine A Potentially Dangerous Mix
University of Virginia Health System

Many herbal remedies could cause a toxic reaction when combined with other prescription or over-the-counter medicines.

Released: 17-Jan-2006 1:40 PM EST
Nurses’ Research Proves Mother Knows Best When Taking Temp
University of Virginia Health System

According to recent research, your mother was always right when she told you not to eat or drink anything before taking your temperature. On average, study participants consuming cold beverages required 15 minutes for their temperature to return to baseline, while those consuming hot beverages returned to baseline after 23 minutes.

Released: 17-Jan-2006 1:50 PM EST
Scientist Honored with Second-Most Cited Research Paper of the Decade
University of Virginia Health System

Wladek Minor's 1997 paper, "Processing of X-ray Differentiation Data Collected in Oscillation Mode," is now the second-most cited scientific paper in the world in the last ten years, according to The Scientist magazine. Minor is from the University of Virginia.

Released: 21-Feb-2006 7:15 PM EST
UVa Scientists Hot on Trail of Therapies for Deadly Lung Failure
University of Virginia Health System

Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung.

Released: 6-Mar-2006 7:05 PM EST
Sex Chromosome Genes Influence Aggression, Maternal Behavior
University of Virginia Health System

It has been well documented that, across human cultures and in most mammals, males are usually more aggressive and less nurturing than females. It's simple to blame male hormones, like testosterone, for male behavior such as aggression. But maybe it's in our genes, too.

Released: 20-Apr-2006 4:35 PM EDT
Blood Pressure Readings Lower when Patients Slow Down
University of Virginia Health System

According to a new study from a team of nurses headed by Melly Turner, R.N., systolic blood pressure can be an average of 14 points higher when taken immediately after arriving in the exam room and sitting on an examination table rather than sitting in a chair with your back supported and feet flat on the floor.

Released: 21-Apr-2006 4:55 PM EDT
Researchers Find Treatment that Reverses Type 1 Diabetes
University of Virginia Health System

Researchers at the University of Virginia Health System have made an exciting discovery: a combination of treatments reversed the course of Type 1 diabetes in mice using human-safe drugs. Using this model, the researchers found that a combined therapy of lisofylline (LSF) and exendin-4 (Ex-4) effectively reversed newly acquired Type 1 diabetes, also called autoimmune diabetes.

Released: 16-May-2006 3:30 PM EDT
Damage from Oxygen May be One Cause of Parkinson’s Disease
University of Virginia Health System

Research by neuroscientists at the University of Virginia Health System shows that oxygen free radicals are damaging proteins in mitochondria, the tiny cellular "˜batteries' of brain cells.

Released: 17-May-2006 4:05 PM EDT
Researchers Uncover Burrowing Secrets of Ulcer Bacteria
University of Virginia Health System

A researcher at the University of Virginia Health System and colleagues have uncovered the secret to the way that Helicobacter pylori infiltrate the stomach lining and cause ulcers.

Released: 6-Jun-2006 3:35 PM EDT
Old Technology Helps Find New Test for Leg Artery Disease
University of Virginia Health System

Who says the 70's are over. Doctors at the University of Virginia Health System are using technology developed in the disco era to invent a new diagnostic test for clogged leg arteries.

Released: 22-Jun-2006 5:15 PM EDT
Researchers Develop a Model for Kaposi’s Sarcoma Research
University of Virginia Health System

In the month that marks the 25th anniversary of the first reported cases of AIDS in the United States, University of Virginia Health System researchers have published pioneering work describing a model system for long-term infection with a virus known as the Kaposi's sarcoma-associated herpesvirus (KSHV), which causes Kaposi's sarcoma (KS)"”the most common AIDS-related cancer worldwide.


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