Scientists use CRISPR to knock down gene messages early in development

Researchers at the Stowers Institute for Medical Research in Kansas City, Missouri, and the Andalusian Center of Developmental Biology at Pablo de Olavide University in Seville, Spain, have harnessed the technology to target gene messages (messenger...
3-Aug-2020 10:55 AM EDT Add to Favorites

Immune system adaptations in cavefish may provide autoimmune disease insight

Cavefish may not seem like a big deal. They’re small, they live in tucked away places humans rarely go, and they’re common enough that you can find them on every continent except Antarctica. But researchers from the Stowers Institute for Medical...
15-Jul-2020 4:25 PM EDT Add to Favorites

Persistent DNA damage in the placenta affects pregnancy outcomes

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome. People with this rare...
15-Jun-2020 2:40 PM EDT Add to Favorites

Joan W. Conaway elected to the National Academy of Sciences

The Stowers Institute for Medical Research is pleased to announce that Joan Weliky Conaway, PhD, a Stowers Investigator since 2001, has been elected a member of the prestigious National Academy of Sciences (NAS) for her distinguished and continuing...
27-Apr-2020 5:35 PM EDT Add to Favorites

What’s old is new again

Drug resistance is a major obstacle in cancer treatment—leading to relapse for many patients. In a new study, published online April 20, 2020, in Nature Cell Biology, researchers from the Stowers Institute for Medical Research, Children’s Mercy...
20-Apr-2020 3:55 PM EDT Add to Favorites

Technologies Converge on Interacting Surfaces in Protein Complexes

Researchers at the Stowers Institute for Medical Research have fine-tuned a method to pinpoint surfaces within large multi-protein complexes that are close to, and likely to be directly interacting with, one another.
9-Apr-2020 4:00 PM EDT Add to Favorites

How the historically misunderstood amyloid helps to store memories

For the first time, scientists from the Stowers Institute for Medical Research and collaborators have described the structure of an endogenously sourced, functioning neuronal amyloid at atomic resolution. The amyloid is composed of self-aggregated...
11-Mar-2020 6:05 PM EDT Add to Favorites

Zeroing in on how a tumor suppressor protein is cast away

Researchers from the Stowers Institute for Medical Research have uncovered new details about several proteins implicated in tumor growth and metastasis, opening a potential avenue for the development of treatments for diseases such as breast cancer.
21-Oct-2019 10:05 AM EDT Add to Favorites

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