Crosstalk between pancreatic cells may drive rare form of diabetes

Joslin researchers show how one form of the rare inherited disease known as mature onset diabetes of the young (MODY) is driven by mutated digestive enzymes generated in pancreatic exocrine cells that are then taken up by neighboring...
20-Jan-2022 2:05 PM EST Add to Favorites

Cracking the code for a new system of cell-to-cell signaling

Joslin discovery about exosomes (cell fragments that regulate other cells) may help to advance RNA gene therapies for many diseases.
22-Dec-2021 4:10 PM EST Add to Favorites

Insulin resistance pinned to cell signaling defects that could act as therapy targets

Insulin resistance in the general population seems likely to be caused by a series of cell-specific signaling defects some of which appear to be sex-specific. In addition, only a portion of the defects are shared with those seen in diabetes,...
20-Sep-2021 7:05 AM EDT Add to Favorites

Newly Discovered Proteins Provide Protection Against Progression of Kidney Disease in Diabetes

Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to research from the Joslin Diabetes Center in Boston.
30-Jun-2021 2:55 PM EDT Add to Favorites

Ancient gut microbiomes may offer clues to modern diseases

Scientists are rapidly gathering evidence that variants of gut microbiomes, the collections of bacteria and other microbes in our digestive systems, may play harmful roles in diabetes and other diseases.
12-May-2021 11:20 AM EDT Add to Favorites

Pain Receptors Linked to the Generation of Energy-Burning Fat Cells: Implications for Obesity Therapy

A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity. According to the new report, published in Nature...
12-Apr-2021 1:05 PM EDT Add to Favorites

Kids’ metabolic health can be improved with exercise during pregnancy: here’s why

BOSTON – (March 25, 2021) – A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring. According to researchers, the key lies with a protein called SOD3, vitamin D and...
30-Mar-2021 11:30 AM EDT Add to Favorites

Routine eye scans may give clues to cognitive decline in diabetes

In older people with type 1 diabetes, damage to the retina may be linked to memory problems and other cognitive conditions.BOSTON – (December 31, 2020) – As they age, people with diabetes are more likely to develop Alzheimer's disease and other...
4-Jan-2021 1:20 PM EST Add to Favorites