Diabetes-in-a-dish model uncovers new insights into the cause of type 2 diabetes

Researchers have developed a novel ‘disease-in-a-dish’ model to study the basic molecular factors that lead to the development of type 2 diabetes, uncovering the potential existence of major signaling defects both inside and outside of the...
3-Sep-2020 11:45 AM EDT Add to Favorites

Transplanted brown-fat-like cells hold promise for obesity and diabetes

A potential therapy for obesity would transplant HUMBLE (human brown-like) fat cells, human white fat cells that have been genetically modified using CRISPR to become similar to heat-generating brown fat cells.
26-Aug-2020 2:15 PM EDT Add to Favorites

Increased blood sugar levels may decrease benefits of aerobic exercise

Researchers at Joslin Diabetes Center have discovered that some benefits of aerobic exercise may be dampened by higher-than-normal blood sugar levels, and that this is independent of obesity and insulin levels in the blood.
20-Jul-2020 12:45 PM EDT Add to Favorites

For the First Time, Study Identifies Time Trends in Pregnancy-Related Outcomes Among American Women with Type 1 Diabetes

Largest US database of pregnant women with type 1 diabetes provides a first-time, big picture view of mother’s health, and neonatal and delivery outcomes. The analysis found a threefold increase in insulin pump use at the end of the study...
1-Jul-2020 10:45 AM EDT Add to Favorites

Promising treatment to slow kidney disease doesn’t prove out in clinical trial

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival. Progression of kidney disease in type 1 diabetes is...
25-Jun-2020 2:55 PM EDT Add to Favorites

Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes

Fewer than one in five adolescents and young adults with type 1 diabetes are successful in achieving the recommended 2019 A1C goal of below 7.5%, and the overwhelming majority fail to achieve the 2020 target of less than 7%. But young people who use...
16-Jun-2020 2:10 PM EDT Add to Favorites

Small rises in blood glucose trigger big changes in insulin-producing cells

This study provides a wealth of new data showing how beta cells behave at slightly raised levels of blood glucose - still within the pre-diabetes range. The work provides major additional evidence of a “glucose toxicity” effect that helps to...
6-May-2020 1:55 PM EDT Add to Favorites

Researchers Identify Potential Early Biomarker to Track Development of Dangerous Non-alcoholic Fatty Liver Disease

Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide. Even in children the numbers are overwhelming, with up to 80 percent of...
6-Apr-2020 5:10 PM EDT Add to Favorites

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