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Key Immune System Genes Identified to Explain High COVID Deaths and Spread in Northern Italy Versus Fewer Cases and Deaths in the South

Not long after the Coronavirus disease (Covid-19) outbreak in China, Italy was hard-hit by the infection and rapidly became one of the countries with the highest mortality rate.
23-Jul-2020 8:05 AM EDT Add to Favorites

Despite Promising Lab Results, Most Precision Medicine Therapies for Mesothelioma Fail in the Clinical Setting

Malignant mesothelioma (MM) is a lethal cancer mainly caused by exposure to asbestos, for which, unfortunately, no current treatment has proven effective, despite the identification of several promising therapeutic targets over the years.
20-Jul-2020 11:25 AM EDT Add to Favorites

Monoclonal Antibody Restores T-Cell Ability to Kill Cancer

A new class of anticancer agents can restore the ability of cytotoxic T lymphocytes (CTLs) to infiltrate the tumor and kill target cells in patients with metastatic non-small cell lung cancer (mNSCLC).
23-Jun-2020 10:55 AM EDT Add to Favorites

Targeting Receptor EphA2 Reduces Bladder Cancer Tumor Growth and Increases Chemotherapy Effectiveness

An international team of investigators has recently discovered that the receptor tyrosine-kinase EphA2 activated by the growth factor progranulin is a tumorigenic driver of bladder cancer progression.
8-Jun-2020 2:05 PM EDT Add to Favorites

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Genetics May Explain High COVID-19 Mortality in Italy, Inform Global Pandemic Response

Researchers predict the Human Leukocyte Antigen (HLA) gene has a key role in shaping immune response to COVID.
29-May-2020 2:40 PM EDT Add to Favorites

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Researchers Silence PRMT5 Gene to Slow Mesothelioma Using Precision Medicine

Silencing of the protein coding gene PRMT5 has possible therapeutic potential for treating Mesothelioma (MM), according to a recent in vitro study published in the Journal of Cellular and Molecular Medicine.
1-May-2020 11:50 AM EDT Add to Favorites

Considerations about current evolution of SARS-nCOV-2 epidemic in Italy

In Italy, a COVID-19 epidemic is raging. This analysis, which might be useful also to forecast the next epidemic trends in the U.S., is briefly recapitulated in the following document.
12-Mar-2020 10:15 AM EDT Add to Favorites

Understanding COVID-19 Origins First Step to Treating Cases, Stopping Spread

“The new virus originating from Wuhan is the third coronavirus that has made the ‘jump’ from animals to humans,” explains Enrico Bucci, Ph.D., professor and research scientist at the Sbarro Health Research Organization (SHRO), at Temple...
9-Mar-2020 8:55 AM EDT Add to Favorites


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Our Experts on Newswise

‘Genetic Shield’ May Explain Lower COVID Mortality in Southern Italy Compared to North

4-Jun-2020 9:55 AM EDT

Coronavirus: concern and precaution ok, but panic and hysteria unjustified, says expert

COVID-19 is similar in symptoms to the seasonal flu, but to recognize it there is a different procedure and we have to act accordingly
6-Mar-2020 8:20 AM EST

Cancer DNA Sequencing Has Potential, but Not a Magic Bullet, Says Expert

16-Jan-2018 11:05 AM EST

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Thorough Genotyping and Repurposed Drugs Key to Treating Small-Cell Lung Cancer, says Cancer Expert

Cancer expert Antonio Giordano, MD, PhD, Director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, describes the recent progress and future possibilities of treating SCLC.
13-Apr-2017 7:05 AM EDT

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Every Diagnosis of Cancer Should Come with One of These, Says Cancer Expert

“Every cancer diagnosis should come with a referral to genetic counseling,” says cancer expert Dr. Antonio Giordano, President of the Sbarro Health Research Organization at Temple University.
8-Feb-2017 10:30 AM EST

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About

Sbarro Health Research Organization conducts research in cancer, diabetes, and cardiovascular disease. Based in Philadelphia, Pennsylvania on the campus of Temple University, our programs train young scientists from around the globe.

Experts

Contacts

Barbara Colombo

barbaracolombo@ble-group.com

Antonio Giordano
President

president@shro.org

+1215-204-9520

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