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One in Six Patients with Opioid Use Disorder Leaving the Hospital Before Completing Treatment, Potentially Due to Untreated Withdrawal Symptoms

The number of patients admitted with opioid use disorder (OUD) and injection-related infections who left the hospital before completing treatment increased significantly between 2016 and 2020 (from 9.3 percent to 17 percent) according to analysis...
1-Dec-2023 11:00 AM EST Add to Favorites

Lidocaine May Be Able to Kill Certain Cancer Cells by Activating Bitter Taste Receptors

Lidocaine activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. Their findings, published today in...
22-Nov-2023 11:05 AM EST Add to Favorites

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New ‘Patch’ Uses Natural Body Motion to Fix Disc Herniation

A tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression
13-Nov-2023 2:05 PM EST Add to Favorites

Pain Scores, Age Can Help Identify Patients More Likely to Use Few or No Opioids After Surgery

A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them
15-Nov-2023 10:05 AM EST Add to Favorites

Appropriate Statin Prescriptions Increase Sixfold With Automated Referrals

The odds of prescribing the appropriate dose of statins—a medicine used to lower “bad” cholesterol levels—increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods,...
13-Nov-2023 8:30 AM EST Add to Favorites

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Companion Penn Medicine Studies on AAV-based Gene Therapies in Non-Human Primates Suggest Integration into Human DNA is Unlikely to Drive Cancer Mutations While Offering the Potential for Durable Expression of the Transgene

Gene therapy adeno-associated viruses (AAVs)—viruses that can be engineered to deliver DNA to target cells—are unlikely to cause cancer-triggering insertions in humans or monkeys and may contribute to long-term efficacy, according to new...
2-Nov-2023 12:00 PM EDT Add to Favorites

Penn Medicine Researchers Develop Gene Editing Approaches for Phenylketonuria Treatment

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals’ genetic ancestry. PKU causes an amino acid—called phenylalanine (Phe)—to build up in the bloodstream.
1-Nov-2023 1:05 PM EDT Add to Favorites

Basser Center for BRCA Awards 2023 Basser Global Prize to Memorial Sloan Kettering Cancer Center’s Kenneth Offit, MD, MPH

The Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania, the world’s first comprehensive center aimed at advancing research, treatment, and prevention of BRCA-related cancers, has announced Kenneth Offit, MD,...
31-Oct-2023 10:05 AM EDT Add to Favorites

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