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St. Jude research featured at the American Society of Hematology Annual Meeting

St. Jude researchers will participate in multiple oral and poster presentations and education sessions as well as moderate panels during the ASH conference.
6-Dec-2023 10:05 AM EST Add to Favorites

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James R. Downing, M.D., recognized as one of Modern Healthcare’s 100 Most Influential People for the second consecutive year

Ranked among the top healthcare leaders and innovators across the country
2-Dec-2023 10:05 AM EST Add to Favorites

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Modular chimeric cytokine receptors improve CAR T–cell therapy for solid tumors

Adding a modular chimeric cytokine receptor to CAR T cells increased their efficacy. Learn how this modular system could improve brain and solid tumor therapy.
30-Nov-2023 11:05 AM EST Add to Favorites

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St. Jude revealed functional targets of oncogenic HOXA9 in high-risk pediatric leukemia

Scientists at St. Jude Children’s Research Hospital identified target genes bound and regulated by HOXA9, a protein overexpressed in high-risk leukemia, extending understanding and opening new possibilities for treatment.
28-Nov-2023 11:05 AM EST Add to Favorites

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Promising target for CAR T cells helps cancer trick the immune system

Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for relapsed and recurrent pediatric leukemia and lymphomas, but not brain and solid tumors.
21-Nov-2023 11:05 AM EST Add to Favorites

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Robust chromatin map explains heterogeneity of pediatric acute lymphoblastic leukemia

Scientists at St. Jude Children’s Research Hospital mapped the difference in chromatin accessibility and regulation in different pediatric acute lymphoblastic leukemia subtypes.
20-Nov-2023 10:05 AM EST Add to Favorites

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Fusion oncoprotein forces cell fates toward rhabdomyosarcoma

Scientists at St. Jude Children’s Research Hospital showed that a fusion oncoprotein can drive molecularly indistinguishable rhabdomyosarcomas arising from both muscle and blood vessel cells.
15-Nov-2023 12:05 PM EST Add to Favorites

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St. Jude scientists identify T-cell differentiation nodes to improve cancer-killing

St. Jude scientists mapped the gene regulatory networks responsible for progressive differentiation states of tumor-infiltrating T cells, using a technology known as single-cell CRISPR screening to knock out or genetically perturb multiple genes...
15-Nov-2023 11:05 AM EST Add to Favorites

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The mission of St. Jude Children’s Research Hospital is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of our founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay.



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