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Cancer, Diabetes, Heart Disease, Genetics, biomolecular chemistry, Oncology

In 1993, Antonio Giordano, M.D., Ph.D., founded the Sbarro Institute with a generous donation from Mario Sbarro, the Founder of the Sbarro restaurant chain, following Dr. Giordano’s discovery of the tumor suppressor gene pRb2. Initially named the Sbarro Institute, the research center was located at Thomas Jefferson University, where Dr. Giordano was a professor.

When Dr. Giordano moved to Temple University in 2002, he and twenty fellow scientists forged a new, three-year alliance with Temple University in Philadelphia, Pennsylvania. Under the new arrangement, the original Sbarro Institute was renamed the Sbarro Health Research Organization, Inc. (SHRO), which includes the Sbarro Institute for Cancer Research and Molecular Medicine at Temple and the SHRO-affiliated laboratory at the University of Siena in Siena, Italy.

Under a 2005 agreement, the Sbarro Institute for Cancer Research and Molecular Medicine received continued funding from Temple and expanded its program to include work on the relationship between obesity and cancer and instituted a new program on molecular therapeutics to explore how molecular genetic research can be applied to patient therapies and diagnostics.

SHRO relies on grants and private donations to fund important biomedical research.

Inflammation, Heart Disease, Vaccine, chronic inflammation, Integrins

Dr. Ley joined LJI in 2007 as the founding Division Head of the Division of Inflammation Biology. Dr. Ley received his B.S. from Altkönigschule-Gymnasium, Kronberg, Germany in 1976. In 1982, he received his M.D. from the Julius-Maximilians-Universität, Würzburg, Germany. Dr. Ley began his postdoctoral training from 1983 to 1987 at the Freie Universität Berlin, Germany. From 1987 to 1989, Dr. Ley was a visiting research scientist at the University of California, San Diego and returned to Freie Universität Berlin until 1994, when he joined the faculty of the University of Virginia. From 2001-2007, he was director of the Robert M Berne Cardiovascular Research Center at the University of Virginia.

Laxmi Mehta, M.D.

Director, Preventative Cardiology and Women's Hear

Ohio State University Wexner Medical Center

Women's Heart Health, Women's Heart Disease, preventative cardiology, Cardiovascular Disease Prevention, Cardiovascular Disease, cardiovascular disease and women, Cardiac Rehabilitation, Cardiac Imaging

Laxmi Mehta, M.D., FACC, FAHA is the Director of the Women’s Cardiovascular Health Program and an Associate Professor of Medicine at The Ohio State University Wexner Medical Center. Dr. Mehta is also the Associate Program Director for Education for Ohio State’s Center for Women’s Health. 

She is the President of the Ohio Chapter of the American College of Cardiology and has previously served two terms as Secretary/Treasurer for the Ohio-ACC Chapter. Additionally, she is the Immediate Past President of the metro Columbus Board of Directors for the American Heart Association and now currently serves on the Great Rivers Affiliate Board for the American Heart Association. She sits on several national committees for both the American College of Cardiology and the American Heart Association. Dr. Mehta was chosen by Business First Magazine as one of Columbus' Top 40 under 40 in 2010 and honored as one of 12 women for the 2012 Women for Economic Leadership (WELD) Women You Should Know Calendar Honoree. 

She specializes in women’s cardiovascular health, prevention and cardiac imaging. Dr. Mehta is an avid promoter and educator on women’s cardiovascular health and has published a number of peer-reviewed articles and book chapters. She is a Fellow of the American College of Cardiology and the American Heart Association. She received her M.D. degree from Northeastern Ohio Universities Colleges of Medicine and Pharmacy in Rootstown, Ohio in 1998. She completed her Internal Medicine residency training and Clinical Cardiology fellowship training at William Beaumont Hospital in Royal Oak, Michigan in 2001 and 2005. 

Ali Tabrizchi, D.O.

Interventional cardiologist

LifeBridge Health

Cardiovascular Disease, Lifebridge Health, Sinai Hospital, Cardiovascular Institute, Angiograms, Coronary Artery Disease, nuclear stress tests, Echocardiogram, Heart Failure, Heart Disease

Dr. Tabrizchi is a clinical interventional cardiologist at the LifeBridge Health Cardiovascular Institute in Maryland. He completed his fellowship at Winthrop-University Hospital. He did his residency at Washington Hospital Center, Children’s National Medical Center and National Institutes of Health (NIH). He completed medical school at Nova Southeastern University of College of Osteopathic Medicine. Dr. Tabrizchi is published in national and international medical journals.

Monocytes, Cancer, Cardiovascular Disease, T Lymphocytes, cancer metastasis, Heart Disease, Plaques, Immune Cells

Hedrick received her B.S. in Biology from Salem College in Winston-Salem, North Carolina in 1984. She received her Ph.D. in Biochemistry from Wake Forest University School of Medicine in 1992, where she performed her graduate research on LDL cholesterol metabolism in the laboratory of Dr Lawrence Rudel. From 1992 to 1995, she performed her postdoctoral research on HDL metabolism in the laboratory of Dr Aldons ‘Jake’ Lusis at UCLA. From 1995 to 1999, she worked as a junior faculty member in the Division of Cardiology at UCLA, where her research focused on inflammation and endothelial function. From 2000 to 2009, Dr. Hedrick worked as a professor in the Departments of Pharmacology, Medicine, and Molecular Physiology and Biological Physics at the University of Virginia in Charlottesville. In 2009, Dr. Hedrick was awarded the Harrison Chair of Molecular Physiology and Biological Physics at the University of Virginia. Dr. Hedrick joined the faculty of LJI in the Division of Inflammation Biology in 2009.

Dr. Hedrick currently serves on the NHLBI Vascular Cellular Molecular Biology Review Committee, the AAI Committee for the Status of Women, and the American Heart Association ATVB Council Leadership Committee. She is also a Fellow of the American Heart Association. Recent honors received by Dr. Hedrick include the ATVB Vascular Biology Special Recognition Award, from the American Heart Association in 2013; the Jeffrey M. Hoeg Arteriosclerosis Thrombosis and Vascular Biology Award for Basic Science and Clinical Research from the American Heart Association in 2014; and the Arteriosclerosis Thrombosis and Vascular Biology Mentor of Women Award from the American Heart Association in 2015.

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