Expert Directory

Food Allergy, Food Allergies, Asthma

Ruchi Gupta, MD, is an Attending Physician, Academic General Pediatrics and Primary Care, at Ann & Robert H. Lurie Children’s Hospital of Chicago and an Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicine. Dr. Gupta also is the Director of the Science and Outcomes of Allergy and Asthma Research Team (SOAAR). Her clinical interests are in the areas of asthma, food allergy, and eczema. She is involved in clinical, epidemiological, and community research. She has been nationally recognized for her research in the areas of food allergy and asthma epidemiology. 

Lgbt, transgender children, Adolescent Medicine, Sexuality, HIV

Robert Garofalo, MD, MPH, is the Division Head of Adolescent Medicine at Ann & Robert H. Lurie Children’s Hospital of Chicago and a Professor of Pediatrics at Northwestern University Feinberg School of Medicine. He is a Co-Director of Lurie Children’s Gender and Sex Development Program, the first comprehensive program for gender nonconforming children and adolescents in the Midwest. Dr. Garofalo also directs Lurie Children’s Adolescent/Young Adult HIV Program and the Center for Gender, Sexuality and HIV Prevention, which conducts research on topics in adolescent sexual health, gender, sexuality, HIV prevention and health disparities affecting adolescent and young adult populations at risk of acquiring HIV. He is a national expert on lesbian, gay, bisexual and transgender (LGBT) health issues in youth, as well as adolescent sexuality and HIV clinical care and prevention. Dr. Garofalo is the former President of the Gay and Lesbian Medical Association. In 2010, he served as a committee member for the National Academy of Sciences/Institute of Medicine Committee on Lesbian, Gay, Bisexual and Transgender Health Issues and Research Gaps and Opportunities.  

genetics and addiction, Animal Behavior, Animal Models, Drug Treatment, Binge Drinking, Risk Factors, alcohol withdrawal; , Reward, Aversion, Taste, selective breedig

I have been working at the VA Medical Center and in the Department of Behavioral Neuroscience at the Oregon Health & Science University in Portland since 1979. I entered graduate school at the University of Colorado to obtain a Ph.D. in social psychology. Fortuitously, I was sidetracked into instead studying behavioral neuroscience (AKA biopsychology) at the fledgling Institute for Behavioral Genetics in Boulder. I’ve been pretty much surrounded by mice ever since. I did post-doctoral work at the University of Wisconsin-
Milwaukee and was a Lecturer in Psychology at San José State and then UC-Santa Barbara, and then held a two-year research position at a Dutch pharmaceutical company in the Dutch hinterlands before Portland.

My research interest is in understanding individual differences in behavioral susceptibility to alcohol and other drugs of abuse, and their genetic and neurobiological bases. Most recently, I’ve been breeding mice that voluntarily drink alcohol until they become intoxicated, i.e. developing a mouse model of university students. I’m working with collaborators to figure out how many genes we’ve affected in the process, which ones they are, and what their biological functions are. We’re using that information to try to predict some drugs that are already FDA approved that might be re-purposed to try as treatments for alcoholism.  My expertise is in mouse behavioral tests that try to capture human traits such as anxiety, sensitivity to drug’s rewarding or aversive effects, incoordination, learning and memory, novelty-seeking, and so forth. I am less fluent in rat than in mouse but the languages are related. 

I am familiar with psychiatric genetics/human genetics methods, but not really expert in the more esoteric of them. I am also familiar with the big data/genomics/informatics approaches, but again not really expert there, either. 
Dr. Lara Ray received her PhD in Clinical Psychology from the University of Colorado at Boulder. During her graduate degree she completed interdisciplinary training in behavioral genetics and neuroscience. Dr. Ray completed a predoctoral clinical internship at Brown University Medical School where she stayed for a postdoctoral fellowship at the Brown University Center for Alcohol and Addiction Studies. After her postdoctoral fellowship, Dr. Ray joined the faculty at the UCLA Clinical Psychology Program where she is now a Full Professor. Dr. Ray also has academic appointments in the UCLA Department of Psychiatry and Human Behavior and the UCLA Brain Research Institute. Dr. Ray has an active program of research on clinical neuroscience of addiction. Her laboratory combines experimental psychopharmacology with behavioral genetic and neuroimaging methods to ascertain the mechanisms underlying addictive disorders in humans and applying these insights to treatment development. Dr. Ray has over 150 peer-reviewed publications and book chapters. Her program of research is funded by the National Institute on Alcohol and Abuse and Alcoholism (NIAAA) as well as the National Institute on Drug Abuse (NIDA). Dr. Ray’s current interest centers around the clinical science informed translation of neurobiological models of addiction to clinical samples. Dr. Ray has received awards from the American Psychological Association (APA) for early career contributions to the science of addiction, including awards from the Society of Addiction Psychology (APA div 50), the Society of Clinical Psychology (APA div 12), and the Research Society for Alcoholism. 

Alcohol, HIV, TBI, metabolic alterations , Muscle, Inflamation

Patricia E. Molina, MD, PhD, is the Richard Ashman Professor and Head of Physiology, and Director of the Alcohol and Drug Abuse Center at LSU Health Sciences Center New Orleans’ School of Medicine.  Dr. Molina's training as a physician prior to completing training in physiology provides her with a unique systems approach to study the biomedical consequences of chronic heavy alcohol use, with emphasis on the pathophysiological mechanisms that aggravate HIV disease progression. Her research focuses on the interaction of chronic alcohol consumption on progression of HIV disease in preclinical models and in translational studies.  Her research involves integrating in vivo with ex vivo approaches to understand the contribution of organ systems to disease pathogenesis. Another area of research interest and ongoing investigations is the interaction of alcohol with outcomes from traumatic brain injury. Her work examines the mechanisms that lead to greater alcohol drinking during the post-injury phase, and the potential role of the endocannabinoid system in modulating those responses. Dr. Molina is interested in translating research findings to the community at large, and in educating the lay public on the consequences of excessive alcohol consumption. This is particularly relevant to young students and parents as they make decisions on alcohol drinking throughout their life.

alcohol use, alcohol use disorder, harm reduction, , Alcohol Use, Alcohol Use Disorder, harm reduction, moderate alcohol consumption, Mindfulness, reductions in drinking, alternatives to Alcoholics Anonymous, behavioral therapy for alcohol, Statistics, alc

Dr. Katie Witkiewitz is a Professor of Psychology at the University of New Mexico with a joint appointment at the Center on Alcoholism, Substance Abuse, and Addictions.  The underlying theme of her research is the development of empirically-based models of alcohol use disorder, with an emphasis on harm reduction and the application of person-centered models to better understand individual changes in alcohol use over time.  Her recent work has focused on novel definitions of alcohol use disorder treatment outcomes that focus on reductions in drinking, as an alternative to an abstinence-only model of alcohol recovery.

Dr. Witkiewitz is also a licensed clinical psychologist and has worked extensively on the development of a theoretical model of biopsychosocial influences on alcohol use and relapse.  This research has led to her collaborative work on the development and evaluation of mindfulness-based interventions for alcohol and drug use disorders.  She has conducted numerous empirical studies on the prediction of alcohol and drug relapse following treatment, mechanisms of successful alcohol treatment outcomes, as well as the development of behavioral interventions to treat addiction.  Her research has been supported by grants from the National Institute on Mental Health, the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism and the National Cancer Institute, totaling over $22 million in research funding since 2004.   

Dr. Witkiewitz was born in Rochester New York and graduated Summa Cum Laude with a Bachelor of Arts degree in psychology from the State University of New York at Potsdam in 1999. She completed a Masters of Arts degree at the University of Montana in 2000 and her doctoral degree at the University of Washington in 2005 under the direction of Dr. G. Alan Marlatt. To date, she has authored 5 books, over 185 peer-reviewed publications and book chapters, and she has given over 75 presentations and invited talks. 

Ralph Hingson, ScD, MPH

Division of Epidemiology and Prevention Research

Research Society on Alcoholism

epidemiolgy, Prevention, Underage Drinking, College Drinking, program evaluation, Policy, Alcohol

Dr. Ralph Hingson is the Director of the Division of Epidemiology and Prevention Research at the National Institute on Alcohol Abuse and Alcoholism (NIAAA).  Before joining NIAAA, he was Professor and Associate Dean for Research at the Boston University School of Public Health.  He has authored or co-authored 170 research articles and book chapters, including studies of the effects of: (1) Raising the legal drinking age, (2) Zero tolerance laws for drivers under 21, (3) .08% legal blood alcohol limits for adult drivers, (4) comprehensive community programs to reduce alcohol problems, (5) early drinking onset on alcohol dependence, traffic crashes, unintentional injuries and physical fights after drinking, as well as 6) assessments of morbidity and mortality associated with underage drinking, drinking by U.S. college students ages 18-24, and interventions to reduce both underage and college drinking.  Dr. Hingson currently serves on the World Health Organization coordinating council to implement WHO’s global strategic plan to reduce the harmful use of alcohol. 

In recognition of his research contributions, the Robert Wood Johnson Foundation honored Dr. Hingson in 2001 with its Innovators Combating Substance Abuse Award.  In 2002, he received the Widmark Award, the highest award bestowed by the International Council on Alcohol Drugs and Traffic Safety (ICADTS). Dr. Hingson is a Past President of ICADTS.  In 2003, Mothers Against Drunk Driving instituted the Ralph W. Hingson Research in Practice Annual Presidential Award, with Dr. Hingson honored as its first recipient.  In 2008, the American Society of Addiction Medicine conferred the R. Brinkley Smithers Distinguished Scientist Award to Dr. Hingson. In 2014, he received the University of Pittsburgh Legacy Laureate Award. In 2016, he received ICADTS’ Borkenstein Award for “Outstanding contributions to international cooperation in alcohol and drug related traffic safety programs.” In September of 2017, Dr. Hingson will receive will receive a National Institutes of Health (NIH) 2017 Director's Award for his role as a member of the Surgeon General's Report Team for the recently-released Surgeon General’s Report on Alcohol, Drugs, and Health. 

alcohol tolerance, Alcohol Consumption, genetics and addiction, Neurobiology

Professor, Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO.

Research has focused on neural mechanisms of adaptation to alcohol, including tolerance and dependence.  Identified a  role of peptide hormones and brain growth factors to modify alcohol tolerance.  

Discovered that one subtype of glutamate receptor, the NMDA receptor, is very sensitive to alcohol, and that increases in NMDA receptor function are involved in alcohol dependence.  This work has led to many further studies by others that focus on the role of the brain  glutamate systems in addiction to alcohol and other drugs.  

Currently focus on systems genetic analysis, using "big data" to understand the genetic contribution to alcohol-related and other complex behaviors.

Kenneth Sher, PhD

Curators' Distinguished Professor

Research Society on Alcoholism

Alcohol

Kenneth J. Sher, Ph.D., is a nationally renowned scholar, researcher, and mentor whose work has greatly advanced our understanding of the etiology and course of alcohol use disorder (AUD), particularly as it relates to personality traits and their evolution. Dr. Sher has been at the forefront of research on personality, alcohol misuse among college students, and the behavioral pharmacology of alcohol. He is also a highly regarded expert in longitudinal research methodology. Over the course of his career, Dr. Sher has studied a wide range of topics contributing substantially to our understanding of the development of alcohol and other substance misuse. He has examined risk mechanisms that influence AUD onset and progression, premorbid predictors of future AUD (e.g., cognitive mechanisms and individual differences in the psychopharmacological responses to alcohol), and the involvement of family history of alcoholism in multiple etiological pathways to AUDs. 

His diverse research interests include: personality, as well as developmental changes in personality, as predictors of alcohol misuse and AUD; gene-environment interactions in the development of AUD; and predictors and consequences of binge drinking and alcohol misuse among college students (including 21st birthday drinking and other extreme drinking occasions). Dr. Sher has also investigated the phenomenon of “maturing out” of alcohol problems, demonstrating that maturing out is associated with differences in age-related personality changes that are accompanied by decreased impulsivity and neuroticism and is not merely a consequence of constrained opportunity occasioned by the assumption of adult roles. 

Dr. Sher had led two major ongoing longitudinal cohort studies that have followed individuals beginning in their freshman year of college and into mid-life. In addition to the development of AUD, this research tracks drug use and comorbid psychiatric disorders. A particularly innovative aspect of this work is the incorporation of genotyping which may provide key information on individual differences in susceptibility to AUD. 

In addition to using traditional survey approaches, Dr. Sher’s research employs event-based data to capture the momentary moods, motivational states, and cues that precede drinking events. This work is critical to understanding transient influences on drinking behavior and related consequences on a given occasion. 

A major focus of his current work is the critical evaluation of existing diagnostic approaches and development of empirically-based criteria and algorithms for AUD diagnosis. This research holds promise for improving AUD diagnosis in clinical practice, and advancing research on the causes and correlates of AUD.

Dr. Sher has been continually funded by NIAAA for more than 30 years. He has had more than 250 papers published in peer-reviewed journals and he has authored and edited several books. 

Dr. Sher earned his undergraduate degree from Antioch College, his Ph.D. in clinical psychology from Indiana University, and completed clinical internship training at Brown University. He is the Curators’ Distinguished Professor of Psychological Sciences at the University of Missouri, where he directs a pre and postdoctoral training program in alcohol research.

Alcohol, Alcoholism, Drug Abuse, Mental Health

Tom Greenfield, PhD, is Scientific Director of the Public Health Institute’s Alcohol Research Group, in Emeryville California, which involves 15 multi-disciplinary research scientists bringing a broad range of expertise to bear on alcohol, other drug and mental health problems.  Since 1995 Greenfield led and now co-lead the bi-decadal National Alcohol Surveys (NASs) conducted by the NIAAA-funded National Alcohol Research Center, that he directed from 1999 to 2015 (P50 AA005595, Years 20-35). Over time, the NAS has incorporated measures and interview modalities that he helped refine in a series of methodological studies.  Greenfield trained as a clinical psychologist, afterwards adding epidemiological and health services expertise in part through postdoctoral years at the UCSF Department of Psychiatry.  Educated at Caltech, MIT and the University of Michigan, he has authored or coauthored over 250 peer-reviewed articles, chapters, books and monographs.  Many are on health effects of alcohol and alcohol policy, often in collaboration with senior colleagues, early career scientists, and postdoctoral fellows.  In addition to participating in many national and international projects, Dr. Greenfield has led numerous R-mechanism National Institutes of Health projects on such topics as alcohol policy evaluation, health disparities and alcohol-related mortality, alcohol intake measurement, and comparative cross-national studies.  He currently leads two team-based Alcohol's Harms to Others R01 grants funded by NIAAA. One, together with his ARG colleague Dr. Katherine Karriker-Jaffe, examines ways that secondhand drinking can victimize partners, families, children, coworkers, and communities, using metrics such as the damage to mental health, health quality of life, and a family’s finances.  A second is a similar multinational collaboration involving standardized questionnaires in over 30 countries that surveyed victims and perpetrators of alcohol’s harms, and involves multiple PIs and 15 international co-investigators.  Both grants are examining in depth state and national policies, contextual, and protective influences, and ways to best reduce the toll of alcohol’s harms to communities.  

Selected recent publications:
Wilsnack, S.C., Greenfield, T.K., Bloomfield, K.A., (in press). The GENAHTO Project (Gender and Alcohol's Harm to Others): design and methods for a multinational study of alcohol's harm to persons other than the drinker. International Journal of Alcohol & Drug Research.
Greenfield, T. K. & Martinez, P. (2017) Alcohol as a risk factor for chronic disease: raising awareness and policy options. In: Giesbrecht, N. & Bosma, L. (Eds.), Preventing Alcohol-Related Problems: Evidence and Community-based Initiatives (pp 33-50). Washington, DC: APHA Press.
Greenfield, T.K., Ye, Y., Lown, E.A., Cherpitel, C.J., Zemore, S., & Borges, G. (2017) Alcohol use patterns and DSM-5 alcohol use disorder on both sides of the US-Mexico border. Alcoholism: Clinical & Experimental Research 41:769-778. [DOI: 10.1111/acer.13356] PMICD: PMC5378627 
Greenfield, T.K., Karriker-Jaffe, K.J., Kerr, W.C., Ye, Y., & Kaplan, L.M. (2016) Those harmed by others’ drinking are more depressed and distressed, Drug and Alcohol Review, 35(1):22-29 [doi: 10.1111/dar.12324]. PMCID: PMC4775452
Greenfield, T.K., Bond J., Kerr W.C. (2014) Biomonitoring for improving alcohol consumption surveys: the new gold standard? Alcohol Research: Current Reviews 36(1): 39-44. PMCID: PMC4432857
Greenfield, T. K. (2013) [Editorial] Alcohol (and other drugs) in public health research. American Journal of Public Health 103(4):582.

Gene Expression and Regulation, Drug Discovery, Receptor Proteins, immune signaling, Neuroscience

I have almost 40 years of experience in the field of alcoholism research, with much of my work focusing on the molecular sites and mechanisms of alcohol action in brain. My group has extensive experience with mouse behavioral models of alcohol consumption and dependence and was involved in some of the initial studies of the neuroimmune basis of alcohol dependence. Profiling brain gene expression is key to understanding addiction, and we were among the first to study the human brain transcriptome. We have implemented microRNA profiling and next-generation sequencing to extend our studies of molecular remodeling by alcohol in human and mouse brain. We study the genetic overlap in human alcoholics and animal models of alcohol dependence and examine the neurobiological systems involved. My research encompasses the fields of genomics, behavior, systems biology, and bioinformatics. Overall, my work has combined functional, structural, behavioral, and genomic approaches to define sites of alcohol action. Currently, I am Associate Director of the Waggoner Center for Alcohol and Addiction Research at The University of Texas at Austin and previously served as Director for 20 years. I am also the Consortium Director for the Integrative Neuroscience Initiative on Alcoholism (INIA)-Neuroimmune, where our goal is to identify and test candidate drugs that may be repurposed to treat alcohol use disorders. 

Jenny Chang, MD

Director, Houston Methodist Cancer Center

Houston Methodist

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Chang's work focuses on the therapy resistance of cancer stem cells, which has led to several publications and international presentations. Her clinical research aims to evaluate novel biologic agents in breast cancer patients. Chang has worked in the field of tumor-initiating cells for more than 10 years. After her discovery that tumor-initiating cells are chemo-resistant, and that targeting the EGFR/HER2 pathway can decrease this subpopulation, Chang played a key role in demonstrating some of the limitations and mechanisms of tumor-initiating cells. Her work is now focused on the mechanisms that regulate TICs, as well as initiating and planning clinical trials that target this critical tumor initiating subpopulation. She is also interested in characterizing the cross-talk between these different pathways that may lead to mechanisms of resistance, and has identified some of the chief regulatory pathways involved in TIC self-renewal. She is a world-renown clinical investigator, credited as one of the first to describe intrinsic chemo-resistance of tumor-initiating cells.

Marco Mielcarek, MD

Medical Director of the Adult Blood and Marrow Tra

Seattle Cancer Care Alliance

Cancer, Bone Marrow, Oncology, Blood Cancers, Stem Cell, Transplantation

Dr. Mielcarek believes that individualizing treatment according to the patient's needs and philosophy, combined with incorporating up-to-date research knowledge, are key ingredients for excellent patient care.
Clinical Expertise

    Blood stem cell and bone marrow transplantation for hematologic malignancies
    Graft-versus-Host Disease (GVHD)

Title

    Medical Director, Adult Blood and Marrow Transplant Program, Seattle Cancer Care Alliance
    Member, Clinical Research Division, Fred Hutch
    Professor of Medicine, Department of Medical Oncology, University of Washington

Education and Training

    MD: Freie Universität Berlin, 1986
    PhD: Freie Universität Berlin, 1987
    Residency: Freie Universität Berlin, Internal Medicine, 1987-1993
    Research Fellowship: Fred Hutchinson Cancer Research Center, 1994-1999
    Residency: University of Washington, Internal Medicine, 1999-2000
    Fellowship: University of Washington, Medical Oncology, 2000-2003

James Hendler, PhD

Director, Future of Computing Institute

Rensselaer Polytechnic Institute (RPI)

Artificial Intelligence, Semantic Web, Internet, Big Data, Machine Learning, technology policy

James Hendler is the Director of the Future of Computing Institute; Tetherless World Professor of Computer, Web and Cognitive Sciences; and Director of the RPI-IBM Artificial Intelligence Research Collaboration. 

Hendler is a data scientist with specific interests in open government and scientific data, data science for healthcare, AI and machine learning, semantic data integration, and the use of data in government. One of the originators of the Semantic Web, he has authored over 450 books, technical papers, and articles in the areas of Open Data, the Semantic Web, artificial intelligence, and data policy and governance. He is also the former Chief Scientist of the Information Systems Office at the US Defense Advanced Research Projects Agency (DARPA) and was awarded a US Air Force Exceptional Civilian Service Medal in 2002. He is the first computer scientist ever to have served on the Board of Reviewing editors for Science. In 2010, Hendler was selected as an “Internet Web Expert” by the US government and helped in the development and launch of the US data.gov open data website. In 2013, he was appointed as the Open Data Advisor to New York State and in 2015 appointed a member of the US Homeland Security Science and Technology Advisory Committee. In 2016, became a member of the National Academies Board on Research Data and Information, in 2017 a member of the Director’s Advisory Committee of the National Security Directorate of PNNL, and in 2021 became chair of the ACM’s global Technology Policy Council. Hendler is a Fellow of the US National Academy of Public Administration, the AAAI, AAAS, ACM, BCS and IEEE.

Andrew Mammen, MD, PHD

PI, unit lead muscle unit NIAMS

Myositis Association

Myositis, Inclusion Body Myositis, Dermatomyositis, Polymyositis, necrotizing myopathy, HMGCR myositis, antisynthetase syndrome

Andrew Mammen, MD, PhD works at the National Institute of Arthritis and Musculoskeletal and Skin Diseases as Muscle Disease Unit Leader in the Laboratory of Muscle Stem Cells and Gene Regulation. Prior to his appointment at NIH, he was Associate Professor of Neurology and Medicine at the Johns Hopkins University School of Medicine. He co-founded the Johns Hopkins Myositis Center in 2007, where he continues to see myositis patients as an adjunct faculty member. Dr. Mammen and his colleagues at Hopkins discovered a novel form of autoimmune myopathy associated with statin use and autoantibodies recognizing HMG-CoA reductase, the pharmacologic target of statins. In addition to clinical studies involving myositis patients, his current laboratory research interests include defining pathogenic mechanisms in the various forms of autoimmune myopathy and understanding the role of myositis autoantigens in muscle regeneration.

Conservation, Endangered Species, Wolves

My research is centered on understanding and explaining how people make conservation-related judgments and decisions, and the intersection of such judgments with conservation policy.  I am particularly interested in how people make decisions related to the conservation of wildlife, and the origins of resource-related conflicts, especially those that involve wildlife. Much of my recent work is focused on understanding judgments and behaviors concerning large carnivores.

Natural resources-related values, attitudes, behaviors
Natural resources conflicts
Wildlife management and policy
Human-wildlife conflict

Juergen Hahn, PhD

Department Head, Biomedical Engineering

Rensselaer Polytechnic Institute (RPI)

Autism, Autism diagnosis, Autism Treatment And Research, Big Data, big data and medicine

Juergen Hahn, Department Head of Biomedical Engineering at Rensselaer Polytechnic Institute, is a trailblazer in the use of big data methods to improve the diagnosis and treatment of Autism. His research focuses on the use of machine-learning algorithms to analyze complex biological and biomedical systems. He previously developed a physiological test for autism after discovering patterns with certain metabolites in the blood that can accurately predict diagnosis. He is applying that same approach to other areas of autism research including correlating conditions and assessing the effectiveness of possible medical treatments.

Ebola, Lassa Fever, cryo-electron microscopy, Ebola Virus, Marburg, zoonotic disease, Infectious Disease, Vaccines, Antibodies, Rabies, SARS COV-2, Coronavirus, covid, Virology, Biology, Medicine, Health, Global Health, Structural Biology

Erica Ollmann Saphire, Ph.D. serves as President and CEO of the La Jolla Institute for Immunology. She is one of the world’s leading experts in pandemic and emerging viruses, such as Ebola, Marburg and Lassa. Dr. Saphire directs the Viral Hemorrhagic Fever Immunotherapeutic Consortium (VIC), an NIH-funded Center of Excellence in Translational Research. The VIC unites 43 previously competing academic, industrial and government labs across five continents to understand which antibodies are most effective in patients and to streamline the research pipeline to provide antibody therapeutics against Ebola, Marburg, Lassa and other viruses. Dr. Saphire's research explains, at the molecular level, how and why viruses like Ebola and Lassa are pathogenic and provides the roadmap for developing antibody-based treatments. Her team has solved the structures of the Ebola, Sudan, Marburg, Bundibugyo and Lassa virus glycoproteins, explained how they remodel these structures as they drive themselves into cells, how their proteins suppress immune function and where human antibodies can defeat these viruses. A recent discovery revealed why neutralizing antibodies had been so difficult to elicit against Lassa virus, and provided not only the templates for the needed vaccine, but the molecule itself: a Lassa surface glycoprotein engineered to remain in the right conformation to inspire the needed antibody response. This molecule is the basis for international vaccine efforts against Lassa.

Dr. Saphire is the recipient of numerous accolades and grants, including the Presidential Early Career Award in Science and Engineering presented by President Obama at the White House; the Gallo Award for Scientific Excellence and Leadership from the Global Virus Network; young investigator awards from the International Congress of Antiviral Research, the American Society for Microbiology, American Society for Biochemistry and Molecular Biology, and the MRC Centre for Virus Research in the United Kingdom; the Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund, and the Surhain Sidhu award for the most outstanding contribution to the field of diffraction by a person within five years of the Ph.D. Dr. Saphire has been awarded a Fulbright Global Scholar fellowship from the United States Department of State and a Mercator Fellowship from the German research foundation, Deutsche Forschungsgemeinschaft, to develop international collaborations around human health and molecular imaging through cryoelectron microscopy.

Dr. Saphire received a B.A. in biochemistry and cell biology and ecology and evolutionary biology from Rice University in Houston, Texas, and a Ph.D. in molecular biology from Scripps Research. She stayed on at Scripps Research as a Research Associate to conduct postdoctoral research and rose through the ranks to become a Professor in the Department of Immunology and Microbiology. In early 2019, Dr. Saphire joined La Jolla Institute for Immunology to establish a molecular imaging facility for cryo-electron microscopy (cryo-EM) at the Institute. The extremely detailed images produced by cryo-EM reveal precisely how essential mechanisms of the immune system operate.

Doug Hales, PhD, MBA

Professor of Operations & Supply Chain Management

University of Rhode Island

Trade, trade and transportation, Supply Chain, Supply Chain & Logistics Management, Supply Chain Management, Business, Tariff, Tariffs, Cold Chain, Lean & Process Improvement, transportation logistics, Operations Management

Douglas Hales is an Associate Dean and Professor of Supply Chain Management at the University of Rhode Island. His primary teaching expertise is Global Supply Chain Management and Lean Six Sigma. His research interests include Global Port Competitiveness and Applied Process Improvement. 

Hales has more than 20 years of operational and supply chain management experience for the U. S. Marine Corps as well as the plastics and construction industries. He can speak to the impact of U. S. imposed tariffs on Chinese goods and U. S. goods in many industries. He can discuss the delay between the tariffs and the arrival of goods being shipped to the U.S. and what consumers can expect, in terms of the timing of price hikes on goods purchased by Americans. He can discuss the “cold chain,” agricultural goods, electronics and commodities in general that ship by container vessel.

Hales is a special issue co-editor for the Transportation Journal on Seaport Competition for 2018 and 2019, as well as the past Program Chair of the Northeast Decision Sciences Institute. He is also the incoming President of the Northeast Decision Sciences Institute, beginning July 1, 2019.

https://web.uri.edu/business/meet/doug-hales/

Politics, Presidential Leadership, Puerto Rico, Immigration, Border Politics, race and politics, Religion And Politics, Citizenship, US citizenship

An assistant professor in the Department of Politics at Ithaca College’s School of Humanities and Sciences, Figueroa can discuss U.S. political issues, including presidential leadership, racial, religious and working class politics, U.S.-Puerto Rico policy, and immigration/border politics.

Figueroa’s academic research focuses on American political development; race, religion and citizenship; Black American politics and political thought; Latino politics and border studies; public leadership; and U.S. Quakers. He is currently finishing a book on Quakers, race and U.S. Empire. His research also focuses on Bayard Rustin, a Black, gay, Quaker labor and civil rights activist of the 1940s through 1980s. He is also working on a project about the everyday “lived experiences” of people who study and/or work near the U.S.-Mexico border.
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