Dr. Ley joined LJI in 2007 as the founding Division Head of the Division of Inflammation Biology. Dr. Ley received his B.S. from Altkönigschule-Gymnasium, Kronberg, Germany in 1976. In 1982, he received his M.D. from the Julius-Maximilians-Universität, Würzburg, Germany. Dr. Ley began his postdoctoral training from 1983 to 1987 at the Freie Universität Berlin, Germany. From 1987 to 1989, Dr. Ley was a visiting research scientist at the University of California, San Diego and returned to Freie Universität Berlin until 1994, when he joined the faculty of the University of Virginia. From 2001-2007, he was director of the Robert M Berne Cardiovascular Research Center at the University of Virginia.
“If I had known back then what we know now, I would have studied immunology earlier. The immune system is the way to manipulate inflammation, prevent and cure many diseases, including cardiovascular disease.”
“We knew atherosclerosis had an inflammatory component but until recently didn’t have a way to counteract that. We now find that our vaccination actually decreases plaque burden by expanding a class of protective T cells that curb inflammation.”
At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.
22-Jul-2020 08:05:39 PM EDT
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