Researchers at UT Southwestern Medical Center have discovered a hormone pathway that potentially could lead to new ways of treating type 1 diabetes independent of insulin, long thought to be the sole regulator of carbohydrates in the liver.
New evidence has emerged from studies in mice that short telomeres or “caps” at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists.
People with type 1 diabetes, whose insulin-producing cells have been destroyed by the body’s own immune system, are particularly vulnerable to a form of inflammatory heart disease caused by a different autoimmune reaction. Scientists at Joslin Diabetes Center now have revealed the exact target of this other onslaught.
A daily dose of safflower oil, a common cooking oil, for 16 weeks can improve such health measures as good cholesterol, blood sugar, insulin sensitivity and inflammation in obese postmenopausal women who have Type 2 diabetes, according to new research.
Diabetes patients who take their medication more consistently have slightly lower health care costs.
Americans consume more than 22 teaspoons of sugar daily - half is through sweetened beverages but the new beverage labeling initiative may show consumers how to stop being "sickeningly sweet."
On March 28, leading experts across multiple disciplines will convene at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes to review the latest research on bariatric surgery as a treatment option. The three-day meeting, hosted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City, will bring together physicians, scientists and policymakers representing 60 countries. The Congress director is Dr. Francesco Rubino, one of the world's leading authorities on bariatric surgery for diabetes.
Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process.
An inexpensive type 2 diabetes drug that has been around for more than 15 years works just as well and has fewer side effects than a half-dozen other, mostly newer and more expensive classes of medication used to control the chronic disease, new Johns Hopkins research suggests.
Scientists, physicians, and other health care practitioners are gathering in Doha to present and share the latest scientific research on the causes and treatment of diabetes, obesity and the metabolic syndrome at the XVII International DALM Symposium hosted by Qatar Foundation and Weill Cornell Medical College in Qatar and the Giovanni Lorenzini Medical Foundation in Milan, Italy and Houston, Texas.
New research may be relevant to how a mother’s diet during pregnancy influences obesity in her children. Rats fed a high-fat prenatal diet had offspring that were obese, an effect prevented by prenatal antixodidants.
The Stony Brook University School of Dental Medicine is leading a multicenter National Institutes of Health-sponsored clinical trial to evaluate whether treatment of chronic periodontitis will help improve diabetes control.
It has been thought that the quality of the physician-patient relationship is integral to positive outcomes but until now, data to confirm such beliefs has been hard to find. Through a landmark study, a research team from Jefferson Medical College (JMC) of Thomas Jefferson University has been able to quantify a relationship between physicians’ empathy and their patients’ positive clinical outcomes, suggesting that a physician’s empathy is an important factor associated with clinical competence. The study is available in the March 2011 issue of Academic Medicine.
Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer’s disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.
Two-thirds of people with diabetes have high blood pressure. Jenna L. Marquard of the University of Massachusetts Amherst is part of a research team developing a home blood pressure test for diabetics that sends the readings automatically to nurses so their medication can be adjusted as needed.
Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.
Insurers and consumers spent $52.2 billion on prescription drugs in 2008 for outpatient treatment of metabolic conditions such as diabetes and elevated cholesterol.
Despite significant advances in kidney care over the past 20 years, efforts to improve therapy for type 1 diabetes patients with kidney dysfunction remain unsuccessful, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that more effective therapies are needed for these patients.
Researchers at the University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego say an evolutionary gene mutation that occurred in human millions of years ago and our subsequent inability to produce a specific kind of sugar molecule appears to make people more vulnerable to developing type 2 diabetes, especially if they’re overweight.
A research team, led by La Jolla Institute scientist Joel Linden, Ph.D., has shed new light on the problem of insulin resistance, and identified the key participants in a molecular pathway that holds therapeutic promise for reducing the severity of type 2 diabetes.
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) found that individuals with fatty liver were five times more likely to develop type 2 diabetes than those without fatty liver. This higher risk seemed to occur regardless of the patient’s fasting insulin levels, which were used as a marker of insulin resistance.
A recent study accepted for publication in Endocrinology, a publication of The Endocrine Society, reports for the first time that maternal fructose intake during pregnancy results in sex-specific changes in fetal and neonatal endocrinology.
As childhood obesity rises, more attention is being given to testing children for diabetes. But which test is best for diagnosing diabetes in kids? A University of Michigan C.S. Mott Children's Hospital study shows a popular, convenient blood test is not the best option for diagnosing diabetes in children.
Researchers from Mount Sinai School of Medicine have discovered a novel function of brain insulin, indicating that impaired brain insulin action may be the cause of the unrestrained lipolysis that initiates and worsens type 2 diabetes in humans.
Examining people across the spectrum of type 2 diabetes—from healthy to the full-blown disease—Joslin Diabetes Center scientists have found a molecular pathway that offers novel targets for drugs.
Latinos are twice as likely to develop diabetes as Caucasians, and half the Latinos born in the United States in this century are predicted to get the disease. Helping to meet this challenge, Joslin Diabetes Center’s Latino Diabetes Initiative—a comprehensive effort that combines clinical care, patient education, community outreach, research and healthcare team education—has upgraded its website with additional resources for Latinos with diabetes and their families in both English and Spanish.
Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) in individuals with type II diabetes, according to a study conducted by researchers in Chicago. The study indicates leptin resistance, a common characteristic of diabetes, may help prevent the formation of inflexible, fibrous tissue that develops in ALI and ARDS.
A new clinical trial at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is among the first to test surgery specifically for Type 2 diabetes. The aim of the study is to understand whether surgery can control diabetes, as well or even better than the best medical treatment available today. This is the first study of its kind open to patients who are overweight or mildly obese.
Researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego say that medication education is a key factor in helping patients with diabetes better stick to their drug treatments plans.
Researchers are reporting on a promising new approach to treating diabetic wounds, bed sores, chronic ulcers and other slow-to-heal wounds. It may be possible to speed healing by suppressing certain immune system cells.
Patients can access all the specialists they need to manage their conditions in a single visit.
Diabetes researchers at Washington University School of Medicine in St. Louis have identified a key mechanism that appears to contribute to the blood vessel damage that occurs in people with diabetes.
Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest.
Joslin Diabetes Center researchers have identified a key molecular player that contributes to the increased bleeding that hemorrhagic strokes may cause in people with diabetes.
Breast cancer patients are nearly 50 percent more likely to die of any cause if they also have diabetes, according to a comprehensive review of research conducted by Johns Hopkins physicians.
According to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.
A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), found higher Bisphenol A (BPA) levels in women with polycystic ovary syndrome (PCOS) compared to controls. Furthermore, researchers found a statistically significant positive association between male sex hormones and BPA in these women suggesting a potential role of BPA in ovarian dysfunction.
Approximately 19 million U.S. adults reported receiving treatment for diabetes in 2007, more than double the 9 million who said they received care in 1996.
Depression and diabetes appear to be associated with a significantly increased risk of death from heart disease and risk of death from all causes over a six-year period for women, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Patients with diabetes, kidney disease and anemia who don’t respond to treatment with an anti-anemia drug have a higher risk of cardiovascular disease or death, researchers at UT Southwestern Medical Center have found.
New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called “starvation hormone” affects multiple biological systems, including preventing insulin sensitivity and promoting cell survival.
City Tech Nursing Prof. Kathleen Falk's research indicates that a community-based care plan and regular disease marker monitoring made a difference in health outcomes in patients with obstacles to diabetes management.
More than a quarter million women who gave birth in U.S. hospitals in 2008 had pre-existing diabetes or developed it during their pregnancy.
In addition to fast food, desk jobs, and inertia, there is one more thing to blame for unwanted pounds-our genome, which has apparently not caught up with the fact that we no longer live in the Stone Age.
A myriad of inputs can indicate a body’s health bombard pancreatic beta cells continuously, and these cells must consider all signals and “decide” when and how much insulin to release to maintain balance in blood sugar, for example. Reporting in Nature Chemical Biology last month, researchers at the Johns Hopkins University School of Medicine have teased out how these cells interpret incoming signals and find that three proteins relay signals similar to an electrical circuit.
A La Jolla Institute team, led by leading type 1 diabetes researcher Matthias von Herrath, M.D., has demonstrated the effectiveness of a recently developed computer model in predicting key information about nasal insulin treatment regimens in type 1 (juvenile) diabetes. Development of the software, the Type 1 Diabetes PhysioLab® Platform, was funded through the peer-reviewed grant program of the American Diabetes Association.
Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded $600,000 from the American Diabetes Association (ADA) to study the effect of resveratrol, a chemical compound most notably found in red wine and grapes, on impaired glucose tolerance (IGT) in older adults. IGT occurs when blood glucose levels are higher than normal, but not high enough to be considered diabetes. The condition is also known as prediabetes.
For patients living with diabetes, reducing the amount of salt in their daily diet is key to warding off serious threats to their health, a new review of studies finds.
People at high risk of type 2 diabetes can make their situation worse by eating too much during the holidays.
A new study finds that combining the newer diabetes drug exenatide with insulin provides better blood sugar control in patients with type 2 diabetes than insulin alone and helps promote weight loss.
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