Newswise | Research Alert

Released: 11-Apr-2023 8:05 AM EDT

Could a Novel Small Molecule Slow or Reverse the Effects of Duchenne Muscular Dystrophy?

Federation of American Societies for Experimental Biology (FASEB)

In a new study published in The FASEB Journal, investigators demonstrated the potential of a molecule that may help overcome some of the devastating symptoms of Duchenne muscular dystrophy (DMD), the most common life-limiting congenital neuromuscular disorder. The agent promotes the activity of AMP-activated protein kinase (AMPK), an important fuel-sensing enzyme that is present in all mammalian cells.

Research Alert MEDICINE SCIENCE

Released: 6-Apr-2023 2:45 PM EDT

Expert Pitch

Expert Query

Expert Directory

Research Alert

Filters close

Could a Novel Small Molecule Slow or Reverse the Effects of Duchenne Muscular Dystrophy?

Long-term mortality in individuals diagnosed with cancer during pregnancy or postpartum

Financial toxicity and quality of life among partners of colorectal cancer survivors

Giving pregnant women routine third trimester ultrasound scans could reduce rates of undetected breech pregnancy by 71%, enabling better care before and during labor and improved outcomes for newborns

Vaccination against chickenpox is estimated to significantly reduce varicella cases and deaths in both children and adults and would be cost-effective

New findings support novel combination treatment for head and neck cancers

New research links greater gestational vitamin D in blood and reduced childhood behavioral issues

Evidence-based consensus guidelines on patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain

Study Shows Primary Visual Cortex in Mice Is Highly Sensitive to UV-Green Color Contrast

Interleukin-13 May Become Target for Treating Colon Pain

Researchers Highlight Challenges of Studying Mice, from Noise to Facility Changes

Chemotherapy Drug Increases Kidney Injury in Mouse Model of Lung Cancer

Researchers Examine Dynamics of C. Difficile Toxins and How Leaky Gut Affects Toxicity

Researchers Use Liquid Chromatography–Mass Spectrometry to Explore Circadian Gene Expression in Mouse Kidneys

Researchers Visualize Lung Alveolar Structure in 3D

Researchers Explore Sex Differences in Cardiovascular and Congenital Heart Diseases in People with Down Syndrome

Diabetes Drug Improves Kidney Function and Inflammation

Succinate Protects against Obesity, Metabolic Disease through Brown Fat Protein Expression

Addressing chemical pollution in biodiversity research

First single molecule microscopic visualization of the full-length human BRCA2 protein binding to DNA revealed

Deleting Key Clock Protein Alters Circadian Rhythm of Blood Pressure in Mice

Neoadjuvant Pepinemab in Combination with Nivolumab and/ or Ipilimumab in Resectable Stage III Melanoma

Timing of Adjuvant Immunotherapy in Stage III Melanoma, Does it Matter?

The Association Between Familiarity of the Surgeon-Anesthesiologist Dyad and Post-Operative Patient Outcomes for Complex Gastro- intestinal Cancer Surgery: A Population-Based Study

Researchers Explore Sex Differences in a Transgender College Swimmer

Genes shed light on why men and women experience different depression symptoms

Phase II Trial Studies Effects of Semaglutide Medication in Patients with NASH

Understanding the Employment Impact of Neuromyelitis Optica Spectrum Disorder in the USA

Crop yields reduced by climate extremes

Mothers’ Obesity Damages Blood-brain Barrier in Offspring, Lean Foster Mothers’ Milk May Be Preventive Tool

Researchers Use Colon Organoids to Explore Why Aspirin Protects against Cancer

Microvascular Impairment Caused by Chronic Estrogen Exposure Is Sex-specific

Study Explores How Pressure in the Skull Affects Brain Blood Flow after Brain Injury

Researchers ID Protein Crucial to Lung Endothelial Function, Could Lead to Targeted Treatment for Fibrosis

Women with Obesity and Type 2 Diabetes May Improve Vascular Insulin Resistance through Weight Loss

Kids with Cerebral Palsy Have More Small Muscle Fibers, More Stem Cells in Contractured Muscles

Effects of the Interruption Management Strategy “Stay S.A.F.E.” During Medication Administration

Simulation- vs. Didactic-Based Learning for Rehabilitation Nurses Caring for Patients With Autonomic Dysreflexia

Noticing Acute Changes in Health in Long-Term Care Residents

Immobility and the High Risk of Not Recovering Function in Older Adults

Medication Management in Patients with Polypharmacy

Are Flame Retardants Reaching Offspring through the Breastmilk of Firefighters?

Neutrons reveal key to extraordinary heat transport

How do companies’ climate change initiatives affect market value and greenhouse gas emissions?

Does a child’s mathematical ability have a genetic basis?

Filters