Key Gene Targeted for Possible New Treatment of Chronic Pain
American Physiological Society (APS)
Identifying efficient dairy cattle in a climate of higher temperatures is the goal of one scientist in the Texas A&M College of Agriculture and Life Sciences Department of Animal Science.
A team of researchers documented complete genomes, transcriptomes, and proteomes, and several iron-uptake strategies for two species of Dunaliella algae that need little iron to survive.
Researchers developed a genomics-based computational pipeline to understand how specific strains of bacteria behave within bacterial communities associated with plants.
A team of scientists studied carbon allocation in soils at an artificial tropical rainforest. Their results demonstrated the impact of drought on microbial activity, particularly on how the types of carbon in soil can change, leading to a loss of carbon to the atmosphere as carbon dioxide and volatile organic compounds.
Throughout our lives, changes in our DNA, called genetic mutations, occur in every healthy cell of the human body—mutations which have long been thought to be an important reason why our bodies age. But it’s not known whether some people accumulate mutations at a faster or slower rate with age, and whether those differences might predict how long we live and the risk for aging-related diseases like cancer. With a $3.5 million research project grant from the National Institutes of Health (NIH), Jonathan Shoag, a surgeon-scientist at the Case Western Reserve University School of Medicine and urologic oncologist at University Hospitals Cleveland Medical Center's Urology Institute, and Gilad Evrony, a physician-scientist at New York University (NYU) Grossman School of Medicine and NYU Langone Hospital, seek to answer these critical questions.
The targeted therapy trastuzumab deruxtecan (T-Dxd), an antibody drug conjugate, is now an approved treatment of HER2-low advanced breast cancers. In a new study led by Yale Cancer Center researchers at Yale School of Medicine, their findings revealed important differences in the genetic makeup of HER2-low advanced breast cancers — a discovery that could lead to better treatment options for patients.
In this study of 2,574 participants with obstructive sleep apnea, compared with participants with objective sleep duration of at least seven hours, those sleeping less than seven hours had higher risks of all-cause mortality independent of apnea-hypopnea index. Further studies would be needed to investigate health benefits of extending sleep length among people with obstructive sleep apnea with short sleep duration.
Bahareh Behkam and collaborators have received a $2 million grant from the National Science Foundation (NSF) to continue their fight against airborne pathogens. An associate professor of mechanical engineering, Behkam and her team will use the funding to further develop engineered living systems for indoor air monitoring. Currently, there is a lack of sensitive, specific, affordable, and easy-to-use airborne pathogen monitoring technology and an overwhelming need for innovative approaches to address this challenge.
Annapolis, MD; November 30, 2023—Hung from a common utility pole, a fiber optic cable—the kind bringing high-speed internet to more and more American households—can be turned into a sensor to detect temperature changes, vibrations, and even sound, through an emerging technology called distributed fiber optic sensing.
Computer scientist Dr. Satish Puri is working on ways to organize and search for petabytes of geospatial data. He is developing algorithms that can use data for everything from geophysical trends to social issues. His work will eventually be incorporated into publicly available software for mapping and analytics.
Hospital germs and pathogens are not always transmitted directly from person to person. They can also spread via germ-contaminated surfaces and objects.
Cedars-Sinai investigators found no established link between the use of assisted reproductive technologies and potential problems in DNA methylation that might impact genetic expression or embryonic development.