The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
In a study published in Nature Materials, scientists from the University of California, Irvine describe a new method to make very thin crystals of the element bismuth – a process that may aid the manufacturing of cheap flexible electronics an everyday reality.
Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing — installing multiple point mutations simultaneously across the genome. Researchers from the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.
Which factors determine how quickly a battery can be charged? This and other questions are studied by researchers of Karlsruhe Institute of Technology (KIT) with the help of computer-based simulations.
Australian scientists are exploring how harmful gut bacteria from a poor diet can access the brain and trigger early onset Alzheimer's disease.
Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown to target problem-causing cells and reduce swelling and harmful molecules in mouse models of damaged skin. Details on their findings were published in the May 20 online issue of the Proceedings of the National Academy of Sciences (PNAS).
A study by researchers at Washington University School of Medicine in St. Louis has found that repeat vaccination with updated versions of the COVID-19 vaccine promotes the development of antibodies that neutralize a wide range of variants of the virus that causes COVID-19, as well as related coronaviruses.
Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop. Rapidly mutating viruses such as SARS-CoV-2 can blunt their effectiveness and even render them obsolete.
A new study led by UCLA Health has shown that repetitive practice not only is helpful in improving skills but also leads to profound changes in the brain’s memory pathways.
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications.
Fire ants form rafts to survive flooding, but how do those bonds work? And what can we learn from them? A Binghamton University, State University of New York professor is researching those questions to expand our knowledge of materials science.
As the world presses forward with urgency towards reaching global biodiversity and climate targets by 2030, there must be increased attention to center equity in dialogue and practice when designing ocean conservation, adaptation and development interventions.
Scientists at St. Jude Children’s Research Hospital uncovered a route to blocking activity of protein notorious for eliminating drugs, offering a potential boon to cancer therapy.
Advanced information processing technologies offer greener telecommunications and strong data security for millions, a study led by University of Maryland researchers revealed. A new device that can process information using a small amount of light could enable energy-efficient and secure communications.
Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer’s disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of “old” oligodendrocytes to “old” neurons compared to the male cortex.
Researchers at the Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) are using artificial intelligence to perfect the design of the vessels surrounding the super-hot plasma, optimize heating methods and maintain stable control of the reaction for increasingly long periods.
Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.
.jpg&width=400&height=400)
New insights into how people perceive the human voice are challenging beliefs about which voices we find attractive. Previous studies have linked vocal averageness and attractiveness, finding that the more average a voice sounds, the higher it is rated in attractiveness.
For people with autism, constipation, diarrhea, and abdominal pain often go along with the social struggles and repetitive behaviors that define the condition. This has prompted many to wonder whether gastrointestinal (GI) problems arise due to autism’s behavioral or sensory features, or whether they might instead contribute to them.
PNNL researchers learn to control peptoid “handedness,” one key to precision drug delivery and diagnostics.
Systems controlled by next-generation computing algorithms could give rise to better and more efficient machine learning products, a new study suggests.
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.
A study that used artificial intelligence (AI) and social media posts to assess the rates of depression and anxiety in nearly half of American counties found that the AI-generated measurements produced more reliable assessments than population surveys. The findings are published in Nature Digital Medicine.
These days, detecting a planetary atmosphere tens or even hundreds of light-years from Earth might not sound like such a big deal. Scientists have found signs of atmosphere surrounding dozens of exoplanets over the past two decades.
In a groundbreaking development for addressing future viral pandemics, a multi-institutional team involving Lawrence Livermore National Laboratory researchers has successfully combined an artificial intelligence-backed platform with supercomputing to redesign and restore the effectiveness of antibodies whose ability to fight viruses has been compromised by viral evolution. The work was published in the journal Nature.
Researchers at the Icahn School of Medicine at Mount Sinai have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to produce potential therapeutic effects in patients with neuropsychiatric disorders such as depression and anxiety.
UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer’s disease begins.
A new international research project showed that intervention with mobile vaccination teams in Sierra Leone is an effective way of reaching rural populations to increase COVID-19 vaccination rates.
A team of scientists, with help from Argonne National Laboratory’s Advanced Photon Source, have demonstrated the existence of an elusive state of matter known as quantum spin nematic.
Researchers at the UNC Eshelman School of Pharmacy and the UNC School of Medicine have engineered a probiotic yeast that enhances probiotic absorption in the gut and has the ability to suppress and even reverse inflammation in animals.
Berkeley Lab scientists have achieved record-high energy and power densities in microcapacitors made with engineered thin films, using materials and fabrication techniques already widespread in chip manufacturing.
The world’s largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.
Vigorous exercise burns fat more in males than in females, but the benefits of exercise are broad for both sexes.
PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.
Scientists at Oak Ridge National Laboratory and six other Department of Energy national laboratories have developed a United States-based perspective for achieving net-zero carbon emissions. The roadmap was recently published in the journal Nature Reviews Chemistry.
Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.
Reaching net-zero carbon emissions goals requires finding transformative paths to manage carbon in difficult-to-electrify economic sectors.
A research team from Tufts University School of Medicine and Massachusetts General Hospital is now reporting evidence that hillocks and their stem cells are physiologically distinct from other cells within the lung and consist of a stratified outer layer of scale-like squamous cells that protect an underlying layer of rapidly expanding basal stem cells that are capable of restoring airway tissue after injury.
A new type of bioplastic could help reduce the plastic industry’s environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle.
This method is a major leap forward for scientists investigating how proteins do their jobs in the immune system. “This method basically creates an entire new kind of world of experiments that people can do..."
Europe's forests have already been severely affected by climate change. Thousands of hectares of trees have already died due to drought and bark beetles. Scientists from the University of Vienna and the Technical University of Munich have now investigated which trees can be used for reforestation.
Samples reveal evidence of changes experienced by the surface of asteroid Ryugu, some probably due to micrometeoroid bombardment.
Spinocerebellar ataxia 4 is a devastating progressive movement disorder. A multinational study has now conclusively identified the genetic difference that causes the disease, bringing answers to families and opening the door to future treatments.
In a new study, researchers report on the molecular assembly of one of the most common anti-phage systems – from the family of proteins called Gabija – that is estimated to be used by at least 8.5%, and up to 18%, of all bacteria species on Earth.
Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed in a new study.
A Ludwig Cancer Research study has discovered how a lipid molecule found at high levels within tumors undermines the anti-cancer immune response and compromises a recently approved immunotherapy known as adoptive cell therapy (ACT) using tumor infiltrating lymphocytes, or TIL-ACT.
Scientists have developed a new method for enhancing X-ray microscopy experiments by allowing researchers to adjust experiments based on data that is being collected on the fly, potentially paving the way for more autonomous discovery.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
