Credit: Image: Courtesy of Michael Witcher, Salk Institute for Biological Studies
Top left: Molecular fence posts (shown in green) separate active from inactive chromosomal neighborhoods areas. Top right: RNA polymerase 2 (shown in red) reads genes in active neighborhoods. Bottom left: Intact fences co-localize with areas of gene activity. Areas of overlap show up in yellow. Bottom right: DNA is shown in blue. I .