Curated News: Cell (journal)

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Newswise: Study Details Toxic Elements Found in Stranded Whales, Dolphins Over 15 Years
Released: 21-Feb-2024 8:30 AM EST
Study Details Toxic Elements Found in Stranded Whales, Dolphins Over 15 Years
Florida Atlantic University

Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples. Findings reveal how toxicant levels relate to their sex, breed, age and other demographic factors.

Newswise: Media Tip: A new blueprint for designing high-performance batteries
Released: 20-Feb-2024 10:05 AM EST
Media Tip: A new blueprint for designing high-performance batteries
Argonne National Laboratory

A team of scientists at the U.S. Department of Energy’s Argonne National Laboratory have discovered an intriguing ​“cooperative” behavior among components in batteries that points to an exciting new approach to designing next-generation technologies. The team found that combining two different types of anions, negatively charged ions, with cations, positively charged ions, can significantly improve the overall battery’s performance.

Newswise: Ancient retroviruses played a key role in the evolution of vertebrate brains
Released: 15-Feb-2024 8:05 PM EST
Ancient retroviruses played a key role in the evolution of vertebrate brains
Cell Press

Researchers report in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex brains.

Released: 15-Feb-2024 11:05 AM EST
Do sugar-free candy and gum give you gas? Researchers think they know why
UC Davis Health

Scientists at the UC Davis School of Medicine may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.

Newswise: Discovery of a subset of human short introns that are spliced out by a novel mechanism
Released: 14-Feb-2024 10:05 PM EST
Discovery of a subset of human short introns that are spliced out by a novel mechanism
Fujita Health University

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

Newswise: Satellites unveil the size and nature of the world’s coral reefs
Released: 13-Feb-2024 8:05 PM EST
Satellites unveil the size and nature of the world’s coral reefs
University of Queensland

University of Queensland-led research has shown there is more coral reef area across the globe than previously thought, with detailed satellite mapping helping to conserve these vital ecosystems.

Released: 9-Feb-2024 4:05 PM EST
New strategy for safer CAR T cell therapy in lymphomas
University of Cologne

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

Newswise: New process allows full recovery of starting materials from tough polymer composites
Released: 8-Feb-2024 2:20 PM EST
New process allows full recovery of starting materials from tough polymer composites
Oak Ridge National Laboratory

In a win for chemistry, inventors at the Department of Energy’s Oak Ridge National Laboratory have designed a closed-loop path for synthesizing an exceptionally tough carbon-fiber-reinforced polymer and later recovering all of its starting materials.

Released: 8-Feb-2024 2:05 PM EST
Pharmacological inhibitor protects nerve cells in ALS disease
Newswise Review

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

Newswise: Researchers at UMass Amherst discover key to molecular mystery of how plants respond to changing conditions
Released: 6-Feb-2024 5:05 PM EST
Researchers at UMass Amherst discover key to molecular mystery of how plants respond to changing conditions
University of Massachusetts Amherst

A team of researchers from the University of Massachusetts Amherst recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change—either internally or in the external environment—to thrive in good times or survive the bad times? The research, focused on plants and published in Cell, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.

Newswise: Proteins Suggest a Path to Reduce Drug Resistance in a Form of Cancer
Released: 2-Feb-2024 1:00 PM EST
Proteins Suggest a Path to Reduce Drug Resistance in a Form of Cancer
Pacific Northwest National Laboratory

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed, thanks to a study of proteins and other molecular players.

Released: 1-Feb-2024 1:05 PM EST
UW-Madison researchers first to 3D-print functional human brain tissue
University of Wisconsin–Madison

A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.

   
Newswise: Brain Protein's Virus-Like Structure May Help Explain Cancer-Induced Memory Loss
24-Jan-2024 11:00 AM EST
Brain Protein's Virus-Like Structure May Help Explain Cancer-Induced Memory Loss
University of Utah Health

In a rare but serious complication of cancer, the immune system can start attacking the brain, causing rapid memory loss. What triggers this was largely unknown. Now, researchers at University of Utah Health have found that some tumors can release a virus-like protein, kickstarting an out-of-control autoimmune reaction.

Released: 29-Jan-2024 10:05 AM EST
Protein identified as a potential biomarker and therapeutic target for aggressive neuroendocrine carcinomas
University of California, Los Angeles (UCLA), Health Sciences

UCLA-led research shows targeting the protein UCHL1 could lead to a new therapeutic approach for managing these cancers

Released: 29-Jan-2024 10:05 AM EST
Is lung cancer treatment working? This chip can tell from a blood draw
University of Michigan

Using a chip to process blood samples, doctors can monitor the amount of cancer cells in a patient's blood to determine how well a treatment is working by the fourth week, according to a new University of Michigan study.

23-Jan-2024 11:05 AM EST
Researchers Discover Why One Type of Chemotherapy Works Best in Bladder Cancer
Mount Sinai Health System

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system’s ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

Newswise: Cultivated Meat Production Costs Could Fall Significantly with New Cells Created at Tufts University
22-Jan-2024 5:05 PM EST
Cultivated Meat Production Costs Could Fall Significantly with New Cells Created at Tufts University
Tufts University

In an advance for cultivated meat technology, researchers have developed bovine muscle stem cells that produce their own growth factors, eliminating the need to add the expensive ingredient in the growth media.

Newswise: Decoding how the brain manages the appetite for salt and water
Released: 26-Jan-2024 10:05 AM EST
Decoding how the brain manages the appetite for salt and water
Tokyo Institute of Technology

Staying hydrated and consuming appropriate amounts of salt is essential for the survival of terrestrial animals, including humans. The human brain has several regions constituting neural circuits that regulate thirst and salt appetite, in intriguing ways.

   
Released: 24-Jan-2024 2:05 PM EST
Study In Mice Uncovers New Protective Benefit of Breast Milk
Johns Hopkins Bloomberg School of Public Health

An immune component of breast milk known as the complement system shapes the gut environment of infant mice in ways that make them less susceptible to certain disease-causing bacteria, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

Released: 22-Jan-2024 1:05 PM EST
Protein discovery could help solve prostate cancer drug resistance
Washington State University

Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells’ resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.

12-Jan-2024 5:00 PM EST
Mega-analysis identifies gene variants associated with glaucoma in people of African ancestry
Perelman School of Medicine at the University of Pennsylvania

Analysis aims to fill knowledge gaps and help guide clinical decisions for a group particularly vulnerable to developing glaucoma

Newswise: ‘Mini-placentas’ help scientists understand the causes of pre-eclampsia and pregnancy disorders
Released: 18-Jan-2024 7:05 AM EST
‘Mini-placentas’ help scientists understand the causes of pre-eclampsia and pregnancy disorders
University of Cambridge

Scientists have grown ‘mini-placentas’ in the lab and used them to shed light on how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

Newswise: We Need a Staph Vaccine: Here’s Why We Don’t Have One
11-Jan-2024 11:00 AM EST
We Need a Staph Vaccine: Here’s Why We Don’t Have One
University of California San Diego

A vaccine for Staphylococcus aureus, one of the most common bacterial infections, would be a game changer for public health. No vaccine candidates have succeeded in clinical trials, but nobody knows why. Researchers at UC San Diego may have figured it out.

Released: 11-Jan-2024 1:05 PM EST
Bulky additives could make cheaper solar cells last longer
University of Michigan

An insight into preventing perovskite semiconductors from degrading quickly, discovered at the University of Michigan, could help enable solar cells estimated to be two to four times cheaper than today's thin-film solar panels.

Newswise: Activating cerebellum shows promise for neurocognitive therapy
Released: 11-Jan-2024 11:05 AM EST
Activating cerebellum shows promise for neurocognitive therapy
UT Southwestern Medical Center

A study of mutant models of fragile X syndrome (FXS), a genetic disorder related to autism and intellectual disability, shows that activation of the cerebellum mitigates aberrant responses in sensory processing areas of the brain and improves neurodevelopmental behaviors. The findings, published by UT Southwestern Medical Center researchers in Cell Reports, could offer an opportunity for developing new therapies for neurocognitive disorders.

Released: 11-Jan-2024 10:05 AM EST
CD4+ T cell patterns linked to autoimmune disorders
Osaka University

Researchers from Osaka University find characteristic changes in CD4+ T cell categories and gene programs associated with autoimmune disease.

Newswise: Noninvasive Test for Embryo Quality Could Streamline Fertility Treatment
8-Jan-2024 11:00 AM EST
Noninvasive Test for Embryo Quality Could Streamline Fertility Treatment
University of California San Diego

Researchers from UC San Diego have developed a noninvasive approach for predicting the quality of lab-fertilized embryos using leftover culture medium.

Released: 8-Jan-2024 4:05 PM EST
Life span increases in mice when specific brain cells are activated
Washington University in St. Louis

A new study from Washington University School of Medicine in St. Louis identifies, in mice, a critical communication pathway connecting the brain and the body’s fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.

Released: 8-Jan-2024 11:05 AM EST
SARS-CoV-2 BA.2.86 is less resistant to vaccine, but may be a problem in the lung
Ohio State University

New research shows that the recently emerged BA.2.86 omicron subvariant of the virus that causes COVID-19 can be neutralized by bivalent mRNA vaccine-induced antibodies in the blood, which explains why this variant did not cause a widespread surge as previously feared.

Released: 4-Jan-2024 4:05 PM EST
Treating tuberculosis when antibiotics no longer work
University of Cologne

In cooperation with research partners in Germany and France, the infectious disease specialist Dr Jan Rybniker and his team at University Hospital Cologne and the University of Cologne’s Faculty of Medicine have identified new, antibiotic molecules that target Mycobacterium tuberculosis and make it less pathogenic for humans.

Newswise: Study reveals clues to how Eastern equine encephalitis virus invades brain cells
2-Jan-2024 5:05 PM EST
Study reveals clues to how Eastern equine encephalitis virus invades brain cells
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.

Newswise: Elusive cytonemes guide neural development, provide signaling ‘express route’
Released: 2-Jan-2024 11:05 AM EST
Elusive cytonemes guide neural development, provide signaling ‘express route’
St. Jude Children's Research Hospital

Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.

Released: 26-Dec-2023 8:50 AM EST
Penn Medicine researchers uncover unexpected molecular pattern in Fragile X Syndrome
Perelman School of Medicine at the University of Pennsylvania

Researchers have found new disrupted genes and an unexpected molecular pattern—dubbed BREACHes—related to Fragile X Syndrome (FXS), a genetic disorder estimated by the Centers for Disease Control and Prevention to impact about 1 in 7,000 males about 1 in 11,000 females.

Newswise: New Insights Revealed On Tissue-Dependent Roles of JAK Signaling in Inflammation
18-Dec-2023 3:05 PM EST
New Insights Revealed On Tissue-Dependent Roles of JAK Signaling in Inflammation
Mount Sinai Health System

Patient-specific mutation-engineered mouse reveals how sensory neurons may trigger some allergy conditions but block others, suggesting more precise design of JAK inhibitors is necessary.

Newswise: Discovery: Plants use “trojan horse” to fight mold invasions
Released: 20-Dec-2023 12:05 PM EST
Discovery: Plants use “trojan horse” to fight mold invasions
University of California, Riverside

UC Riverside scientists have discovered a stealth molecular weapon that plants use to attack the cells of invading gray mold.

Released: 19-Dec-2023 2:05 PM EST
Novel Approach Emerging for Rescuing Limbs at Risk
Cincinnati Children's Hospital Medical Center

Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington, DC-based support group. About 54% of these lost limbs were caused by vascular disease, including diabetes and peripheral arterial disease (PAD)

Released: 15-Dec-2023 3:05 PM EST
Microbiome insights found in poop help predict infections in liver transplant patients
University of Chicago Medical Center

Researchers at UChicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop — a key leap forward in exploring the connection between the gut microbiome and overall health.

Released: 14-Dec-2023 8:05 AM EST
Moffitt Researchers Identify Pathway that Controls Breast Cancer Metastasis to the Brain
Moffitt Cancer Center

Moffitt Cancer Center researchers are working to better understand the molecular mechanisms that promote the development and progression of breast cancer brain metastasis to help improve diagnostics and treatments. In a new study published in the December issue of Cell Reports, they report on identifying a cell signaling pathway that controls breast cancer brain metastasis.

Released: 13-Dec-2023 2:05 PM EST
Understanding the risk of cell therapy for heart repair
University of Surrey

A type of cell that plays a crucial role in tissue repair after a heart attack may also inadvertently be why cutting-edge cell therapies cause an increased risk of rhythm disorders, according to a new study from the Universities of Surrey and Oxford.

Newswise: New 'atherosclerosis atlas' sheds light on heart attacks, strokes
Released: 12-Dec-2023 11:05 AM EST
New 'atherosclerosis atlas' sheds light on heart attacks, strokes
University of Virginia Health System

University of Virginia School of Medicine researchers have created an “atlas of atherosclerosis” that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

Released: 11-Dec-2023 2:05 PM EST
Clues to preventing Alzheimer’s come from patient who, despite genetics, evaded disease
Washington University in St. Louis

A woman who never developed Alzheimer's despite a strong genetic predisposition may hold the key to stopping the disease in its tracks.

Newswise: Similarity between vitamin B12 loss and multiple sclerosis revealed
Released: 8-Dec-2023 7:05 PM EST
Similarity between vitamin B12 loss and multiple sclerosis revealed
Sanford Burnham Prebys

In a new study, published online December 8, 2023 in Cell Reports, researchers at Sanford Burnham Prebys, with collaborators elsewhere, describe a novel molecular link between vitamin B12 and MS that takes place in astrocytes – important non-neuronal glial cells in the brain.

Newswise: T cells tackle new 'Pirola' SARS-CoV-2 variant
7-Dec-2023 5:05 PM EST
T cells tackle new 'Pirola' SARS-CoV-2 variant
La Jolla Institute for Immunology

According to new predictions by La Jolla Institute for Immunology (LJI) researchers, if the new SARS-CoV-2 Pirola variant wants to evade T cells, it isn't doing a very good job.

   
Newswise: New cause of diabetes discovered, offering potential target for new classes of drugs to treat the disease
Released: 8-Dec-2023 6:05 AM EST
New cause of diabetes discovered, offering potential target for new classes of drugs to treat the disease
Case Western Reserve University

Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body—a discovery that could provide a new target to treat diabetes.

Newswise: Discovery fuels insights into early developmental disorders
Released: 5-Dec-2023 2:05 PM EST
Discovery fuels insights into early developmental disorders
UT Southwestern Medical Center

A new study led by UT Southwestern Medical Center molecular biologists presents a novel culture system to grow both embryonic and extraembryonic stem cells, potentially providing important insights into the genesis of congenital malformations and early developmental disorders.

Released: 4-Dec-2023 6:05 PM EST
Lipids and diabetes are closely linked
Université de Genève (University of Geneva)

While sugar is the most frequently named culprit in the development of type 2 diabetes, a better understanding of the role of fats is also essential.

Newswise: Leukemia cells activate cellular recycling program
Released: 4-Dec-2023 5:05 PM EST
Leukemia cells activate cellular recycling program
Goethe University Frankfurt

In a recent study, scientists led by Professor Stefan Müller from Goethe University’s Institute of Biochemistry II investigated a specific form of blood cancer known as acute myeloid leukemia, or AML. The disease mainly occurs in adulthood and often ends up being fatal for older patients.

Newswise: Researchers decode aqueous amino acid’s potential for direct air capture of CO2
Released: 4-Dec-2023 11:05 AM EST
Researchers decode aqueous amino acid’s potential for direct air capture of CO2
Oak Ridge National Laboratory

Scientists at the Department of Energy’s Oak Ridge National Laboratory have made a significant stride toward understanding a viable process for direct air capture, or DAC, of carbon dioxide from the atmosphere. This DAC process is in early development with the aim of achieving negative emissions, where the amount of carbon dioxide removed from the envelope of gases surrounding Earth exceeds the amount emitted.

Newswise: First Multi-Chamber Heart Organoids Unravel Human Heart Development and Disease
Released: 29-Nov-2023 6:05 PM EST
First Multi-Chamber Heart Organoids Unravel Human Heart Development and Disease
Institute of Molecular Biotechnology

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists – so far.

Released: 28-Nov-2023 3:05 PM EST
Growing microtumors in a dish helps rapidly identify genes that drive tumor growth
University of Illinois Chicago

The method identified promising targets for precision oncology in two types of cancer



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