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22-Jan-2019 11:00 AM EST
Released to reporters:
18-Jan-2019 10:15 AM EST


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Article ID: 706672

UCLA scientists create a renewable source of cancer-fighting T cells

University of California, Los Angeles (UCLA), Health Sciences

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells — which can give rise to every cell type in the body and which can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells.

17-Jan-2019 1:05 PM EST

Article ID: 706502

Scientists have identified a bone marrow backup system

Stowers Institute for Medical Research

New research from the Stowers Institute for Medical Research has identified a backup for an important biological system – the hematopoietic system, whose adult stem cells constantly replenish the body’s blood supply.

15-Jan-2019 12:05 PM EST

Article ID: 706465

Muscle Stem Cells Can Drive Cancer That Arises in Duchenne Muscular Dystrophy

Sanford Burnham Prebys Medical Discovery Institute

Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD—and identified two genes linked to the tumor’s growth. The research, performed using a mouse model of severe DMD, helps scientists better understand how rhabdomyosarcoma develops in DMD—and indicates that ongoing efforts to develop treatments that stimulate muscle stem cells should consider potential cancer risk. The study was published today in Cell Reports.

15-Jan-2019 8:00 AM EST

Article ID: 706439

UCI-led study reveals how fasting can improve overall health and protect against aging-associated diseases

University of California, Irvine

In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports.

14-Jan-2019 2:05 PM EST

Article ID: 706327

UCLA researchers correct genetic mutation that causes IPEX, a life-threatening autoimmune syndrome

University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

10-Jan-2019 4:05 PM EST

Article ID: 706273

CRISPR, reprogrammed: A new sidekick for the human immune system?

Innovative Genomics Institute

Berkeley scientists have turned CRISPR-Cas9 genome editing technology into a synthetic immune response. Their engineered "ProCas9" is safely turned off until a plant or animal virus infects the cell. ProCas9 can be programmed to initiate an immune reaction in response to specific viral threats, like Zika and West Nile.

10-Jan-2019 12:00 PM EST

Article ID: 706294

New biomarker links cancer progression to genome instability

American Friends of Tel Aviv University

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat. Genome instability can lead to genetic disorders, chronic diseases and a predisposition to cancer.

10-Jan-2019 11:05 AM EST
  • Embargo expired:
    10-Jan-2019 11:00 AM EST

Article ID: 706239

The Pressure’s Off

Harvard Medical School

• Scientists reveal activated structure of a receptor critical for blood pressure, salt homeostasis • Receptor is a target for drugs widely used to treat hypertension

9-Jan-2019 3:30 PM EST

Article ID: 706174

Ratos obesos perdem a ansiedade quando “células zumbis” saem do cérebro

Mayo Clinic

ROCHESTER, Minnesota. — Pesquisadores e colaboradores da Mayo Clinic demonstraram em ratos que a obesidade aumenta o nível de células “zumbis” ou senescentes no cérebro e que essas células, por sua vez, estão ligadas à ansiedade. Quando drogas senolíticas são usadas para limpar essas células, os comportamentos ansiosos nos ratos se dissipam. Esses resultados aparecem na revista Cell Metabolism.

8-Jan-2019 5:05 PM EST

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