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Blood Stem Cell Transplant, bone marrow donor, Bone Marrow Stem Cells, Blood Stem Cells, Blood Stem Cell

Researchers Discover Faster, More Effective Way to Harvest Blood Stem Cells for Bone Marrow Donation

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A multi-institutional research team led by Indiana University School of Medicine scientists has developed a new way to harvest blood stem cells for bone marrow donation that is faster and more effective than the current standard of care.

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Ut Southwestern, Cancer

Researchers Demonstrate RAS Dimers Are Essential for Cancer

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Researchers at UT Southwestern’s Simmons Cancer Center have shown that RAS molecules act in pairs, known as dimers, to cause cancer, findings that could help guide them to a treatment.

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Breast Cancer, Diet, Estrogen, drugs, , Chemotherapy, Therapeutics

Estrogen-Mimicking Compounds in Foods May Reduce Effectiveness of Breast Cancer Treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

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Neural Stem Cell, Neurogenesis, Neurogenetics, Schizophrenia, Adhd Attention Deficit Disorder, Depression, Gene Expression

Genetic ‘Switches’, Mapped for First Time, Drive Human Brain Development

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UCLA researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains and, in some cases, set the stage for several brain disorders that appear later in life

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Virology, Ebola, Marburg, Outbreak, Pandemic

TSRI Scientists Discover Workings of First Promising Marburg Virus Treatment

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Scientists at The Scripps Research Institute have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus.

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pluripotent stem cells, Stem Cells, Hair Follicle, skin organoids, Organoids, skin, Epidermis, Dermis, 3D culture

In Scientific First, Researchers Grow Hairy Skin In A Dish

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Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells—a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers.

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MD Anderson Cancer Center, Breast Cancer, Dcis

New Cancer Model Shows Genomic Link Between Early-Stage and Invasive Breast Cancer Types

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A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ (DCIS) progresses to a more invasive form of cancer say researchers at The University of Texas MD Anderson Cancer Center.

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National Eye Institute (NEI), National Institutes Of Health (NIH), Discovery, Stem Cell, Therapy, Eye Disease, Closer, Clinic, Age Related Macular Degeneration, AMD

NIH Discovery Brings Stem Cell Therapy for Eye Disease Closer to the Clinic

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Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE)—a layer of cells in the back of the eye—are essential for the survival of the retina’s light-sensing photoreceptors. The discovery has advanced efforts to make stem cell-derived RPE for transplantation into patients with geographic atrophy, otherwise known as dry age-related macular degeneration (AMD), a leading cause of blindness in the U.S. The study appears in the January 2 Cell Reports.

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Drug Target, GPCR, Parkinson's Disease, Cell Biology, NMR, Nuclear Magnetic Resonance

New Structure of Key Protein Holds Clues for Better Drug Design

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Nobel laureate Kurt Wüthrich investigates the structure of an important drug target.

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Genetic Disease, Neurofibromatosis 1, NF1

A Cluster of Mutations in Neurofibromatosis Is an Important Risk Factor for Severe Symptoms

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Research shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1. Such information is vital to help guide clinical management and genetic counseling in this complex disease.







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