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Embargo will expire:
24-Sep-2018 3:00 PM EDT
Released to reporters:
21-Sep-2018 3:45 PM EDT

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Article ID: 700944

A Trojan Horse Delivery of Possible Treatment for a Rare, Potentially Deadly, Blood-Clotting Disorder

University of Alabama at Birmingham

In proof-of-concept experiments, researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. Researchers deliver a therapeutic enzyme via the cellular equivalent of a Trojan Horse, using platelets to protect the key enzyme hidden inside.

Released:
21-Sep-2018 3:30 PM EDT

Article ID: 700905

NYU Dentistry Awarded $1.4 Million NIH Grant to Study Tooth Enamel Formation

New York University

The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health, has awarded a grant to researchers at New York University College of Dentistry to identify the role of mitochondria, the power plants of the cell, and redox in enamel formation. The grant provides more than $1.4 million to NYU Dentistry over four years.

Released:
21-Sep-2018 11:05 AM EDT
  • Embargo expired:
    21-Sep-2018 11:00 AM EDT

Article ID: 700813

DNA Vaccine Leads to Immune Responses in HPV-Related Head and Neck Cancer

Perelman School of Medicine at the University of Pennsylvania

A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus (HPV)-related head and neck cancer. Researchers from the Abramson Cancer Center of the University of Pennsylvania tested the immunotherapy approach in two groups of patients with advanced head and neck squamous cell carcinoma (HNSCCa) and found 86 percent showed elevated T cell activity.

Released:
20-Sep-2018 12:05 AM EDT
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  • Embargo expired:
    21-Sep-2018 10:00 AM EDT

Article ID: 700590

Researchers Successfully Train Employees to Respond to Opioid Overdose, Administer Naloxone

New York University

A small study shows that business managers and staff—such as those running coffee shops and fast-food restaurants—can be trained to reverse opioid overdoses, which are known to occur in public bathrooms.

Released:
17-Sep-2018 8:00 AM EDT
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Article ID: 700896

Roswell Park and URMC To Create $19 Million Research Program Focused on Flavored Tobacco

Roswell Park Comprehensive Cancer Center

The expertise of two regional research teams has earned a federal grant of nearly $20 million to create the nation’s first program dedicated to the study of flavored tobacco.

Released:
21-Sep-2018 7:40 AM EDT
  • Embargo expired:
    21-Sep-2018 5:00 AM EDT

Article ID: 700800

It’s Not Just for Kids -- Even Adults Appear to Benefit from a Regular Bedtime

Duke Health

In a study of 1,978 older adults publishing Sept. 21 in the journal Scientific Reports, researchers at Duke Health and the Duke Clinical Research Institute found people with irregular sleep patterns weighed more, had higher blood sugar, higher blood pressure, and a higher projected risk of having a heart attack or stroke within 10 years than those who slept and woke at the same times every day.

Released:
19-Sep-2018 4:00 PM EDT
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Article ID: 700876

Synthetic Organelle Shows How Tiny Puddle-Organs in our Cells Work

Georgia Institute of Technology

Imagine your liver being just a big puddle. Some organelles in your cells are exactly that including prominent ones like the nucleolus. Now a synthetic organelle engineered in a lab at Georgia Tech shows how such puddle organs can carry out complex life-sustaining reaction chains.

Released:
20-Sep-2018 4:00 PM EDT

Article ID: 700878

Full, but Still Feasting: Mouse Study Reveals How the Urge to Eat Overpowers the Signal to Stop

Michigan Medicine - University of Michigan

A new study explores the mystery of what drives eating past the point of fullness, at the most basic level in the brain. It shows that two tiny clusters of cells battle for control of feeding behavior -- and the one that drives eating overpowers the one that says to stop. It also shows that the brain’s own natural opioid system gets involved – and that blocking it with the drug naloxone can stop over-eating.

Released:
20-Sep-2018 3:40 PM EDT
  • Embargo expired:
    20-Sep-2018 2:00 PM EDT

Article ID: 700574

Drug Overdose Epidemic Has Been Growing Exponentially For Decades

Health Sciences at the University of Pittsburgh

Death rates from drug overdoses in the U.S. have been on an exponential growth curve that began at least 15 years before the mid-1990s surge in opioid prescribing, suggesting that overdose death rates may continue along this same historical growth trajectory for years to come.

Released:
16-Sep-2018 8:00 PM EDT

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