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Medicine

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Genome, DNA, Imaging, Cell Biology

New 3D Imaging Reveals How Human Cell Nucleus Organizes DNA and Chromatin of its Genome

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A team of researchers at the University of California San Diego School of Medicine and the Salk Institute for Biological Studies describe development and application of new electron microscopic imaging tools and a selective stain for DNA to visualize the three-dimensional structure of chromatin — a complex of molecules that helps pack six feet of DNA into each cell nucleus, construct chromosomes and control gene expression and DNA replication.

Medicine

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Aacc, 69th AACC Annual Scientific Meeting & Clinical Lab Expo, Laboratory Medicine, diagnostic technology

【New Product】Hexokinase (HK)

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Hexokinase (HK, EC 2.7.1.1) is an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate is the most important product. Hexokinase can transfer an inorganic phosphate group from ATP to a substrate.

Science

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Structural Biology, Rhodopsin, GPRC, arrestin, phosphorylation codes

Effects of a Major Drug Target Regulated Through Molecular “Codes”

The findings, published today in Cell, reveal for the first time components of a G protein–coupled receptor (GPCR) named rhodopsin bound to a signaling molecule called arrestin, both crucial pieces of the body’s intricate cellular communication network. The new discovery further refines a landmark 2015 Nature article that first described the structure of the two molecules in complex together.

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Winning Star Trek Tricorder Device to Be Presented to Experts at the 69th AACC Annual Scientific Meeting

Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT. The winner of the Qualcomm Tricorder XPRIZE competition will present DxtER—a real-life tricorder—at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego. This special session will be the first time that the device is presented to researchers at a U.S. scientific conference.

Medicine

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Penile Microbiome Study, Latent HIV, Autoimmune Disease Barrier, and More in the AIDS and HIV News Source

The latest research, features, and experts on HIV and AIDS.

Science

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Genomics, Metagenomics, High Performance Computing, Supercomputing, Department of Energy Office of Science, Biology, Computing, Ecosystem, Energy, Environment, Protein, Enzyme, Biogeochemistry, soil

DOE User Facilities Join Forces to Tackle Biology’s Big Data

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Through the “Facilities Integrating Collaborations for User Science” (FICUS) initiative, 6 proposals have been selected to participate in a new partnership between the DOE Joint Genome Institute and the National Energy Research Scientific Computing Center, both U.S. Department of Energy user facilities at Lawrence Berkeley National Laboratory.

Medicine

Science

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monk seal, Neomonachus schauinslandi, Alan Scott

Johns Hopkins Experts Available to Discuss Protecting Endangered Species Using DNA Sequencing

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Medicine

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Brain Cancer Experts, Therapy that Targets Cancer Stem Cells, Lung Cancer Hope, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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human antibody therapy, therapeutic antibodies, Biotechnology, Vaccine Development

Researchers Develop New Method to Generate Human Antibodies

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An international team of scientists has developed a method to rapidly produce specific human antibodies in the laboratory. The technique, which will be described in a paper to be published July 24 in The Journal of Experimental Medicine, could speed the production of antibodies to treat a wide range of diseases and facilitate the development of new vaccines.

Science

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Saliva, Molecular Biology, Evolution Biology, Hominids, Protein, MUC7, Sub-Saharan Africa, Neanderthal, Denisovan, homo erectus, oral microbiome

In Saliva, Clues to a ‘Ghost’ Species of Ancient Human

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In saliva, scientists have found hints that a “ghost” species of archaic humans may have contributed genetic material to ancestors of people living in Sub-Saharan Africa today. The research adds to a growing body of evidence suggesting that sexual rendezvous between different archaic human species may not have been unusual.







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