Feature Channels: Clinical Trials

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Released: 26-Feb-2024 9:05 PM EST
Clinical trial tests combination antibody therapy in adults with advanced cancer
Wiley

In an early phase clinical trial, a combination of antibody-based medications targeting the immune system generated promising safety data and anti-tumor activity in individuals with various types of advanced cancer.

Released: 26-Feb-2024 1:05 PM EST
UChicago receives $13.2 million grant to test digital dementia intervention
University of Chicago Medical Center

Neuroscientist Emily Rogalski, PhD, is a principal investigator on a grant from the NIH to support a clinical trial of a telehealth intervention for primary progressive aphasia (PPA).

Released: 26-Feb-2024 12:00 PM EST
Therapeutic utility of human umbilical cord-derived mesenchymal stem cells-based approaches in pulmonary diseases: Recent advancements and prospects
World Journal of Stem Cells

Pulmonary diseases across all ages threaten millions of people and have emerged as one of the major public health issues worldwide. For diverse disease conditions, the currently available approaches are focused on alleviating clinical sympt

Released: 26-Feb-2024 8:05 AM EST
First Drug to Help Reduce Allergic Reactions to Multiple Food Allergies, Tested at Children’s and Emory, Now FDA Approved
Children's Healthcare of Atlanta

Children’s Healthcare of Atlanta and Emory University participated in a nationwide clinical trial showing that a 16-week course of omalizumab, an injectable drug, increased the amount of peanut, tree nuts, egg, milk and wheat that some multi-food allergic children as young as one year could consume without an allergic reaction after exposure.

Released: 23-Feb-2024 1:05 PM EST
Researchers identify new choice of therapy for rare autoimmune disease EGPA
McMaster University

An international team, including researchers from McMaster University and St. Joseph’s Healthcare Hamilton, has identified a new therapeutic for patients with a rare autoimmune disease called eosinophilic granulomatosis with polyangiitis (EGPA). A biologic drug called benralizumab has been shown to be non-inferior to mepolizumab in the treatment of EGPA.

Newswise: Off-the-shelf vaccine offers hope for pancreatic and colorectal cancer patients with KRAS mutations
Released: 23-Feb-2024 10:05 AM EST
Off-the-shelf vaccine offers hope for pancreatic and colorectal cancer patients with KRAS mutations
University of California, Los Angeles (UCLA), Health Sciences

Samara Rahman, 74, enrolled in a clinical trial at UCLA Health that was evaluating an “off-the-shelf” vaccine that is given after surgery to prevent or delay the cancer from coming back in high-risk patients.

Newswise: New LongCOVID research launched by PolyBio's global consortium of scientists
Released: 22-Feb-2024 7:00 AM EST
New LongCOVID research launched by PolyBio's global consortium of scientists
PolyBio Research Foundation

PolyBio Research Foundation today announced the second phase of its LongCovid Research Consortium (LCRC), including the distribution of $15M to fund research and clinical trials.

Newswise: UNC Lineberger named as a national research hub for NIH cancer screening study
20-Feb-2024 12:05 PM EST
UNC Lineberger named as a national research hub for NIH cancer screening study
University of North Carolina Health Care System

UNC Lineberger Comprehensive Cancer Center has been selected as one of nine national research sites for the National Cancer Institute’s newly launched Cancer Screening Research Network, which will evaluate promising and emerging cancer screening technologies.

Newswise: Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA
20-Feb-2024 9:05 PM EST
Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA
University of California San Diego

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.

Newswise: Hackensack University Medical Center Celebrates Heart Month 
with Cardiovascular Successes
Released: 20-Feb-2024 9:00 AM EST
Hackensack University Medical Center Celebrates Heart Month with Cardiovascular Successes
Hackensack Meridian Health

Hackensack University Medical Center’s heart experts are taking this time to celebrate their leadership in cardiovascular care. The hospital is the only center in New Jersey to use a novel method to assess the health of smaller arteries in the heart and pinpoint microvascular disease, which until now has presented a diagnostic challenge. And they are offering patients promising new therapies by participating in high-profile cardiovascular clinical trials.

Released: 19-Feb-2024 8:05 PM EST
Genetic risk prediction for 10 chronic diseases moves closer to the clinic
Broad Institute of MIT and Harvard

As part of a nationwide collaboration, Broad Clinical Labs researchers have optimized 10 polygenic scores for use in clinical research as part of a study on how to implement genetic risk prediction for patients.

Newswise: Eating too much protein is bad for your arteries, and this amino acid is to blame
Released: 19-Feb-2024 8:05 PM EST
Eating too much protein is bad for your arteries, and this amino acid is to blame
University of Pittsburgh

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.

Released: 16-Feb-2024 9:05 PM EST
First human trial shows ‘wonder’ material can be developed safely
University of Edinburgh

A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests.

Released: 15-Feb-2024 7:05 PM EST
New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial
Queen Mary University of London

An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London.

Newswise: Praedicare Leverages AI, Mathematical Models of Disease Progression and Mapping in World’s First In Silico Clinical Trial of Its Kind
Released: 15-Feb-2024 10:00 AM EST
Praedicare Leverages AI, Mathematical Models of Disease Progression and Mapping in World’s First In Silico Clinical Trial of Its Kind
Praedicare

The in silico trial demonstrated 2X the efficacy of the current treatment (>80% vs 39%); 3X shorter treatment time to cure (6 vs 18 months); 1 drug compared to a 3-drug combo for the standard of care; and preclinical results in shorter time than animal models.

Not for public release

This news release is embargoed until 15-Feb-2024 7:00 AM EST Released to reporters: 14-Feb-2024 10:05 AM EST

A reporter's PressPass is required to access this story until the embargo expires on 15-Feb-2024 7:00 AM EST The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 14-Feb-2024 4:05 AM EST
Can Olive Oil Reverse Genetic Predisposition for Alzheimer’s?
Alzheimer's Center at Temple University Lewis Katz School of Medicine

Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.

Newswise: New Trial Highlights Incremental Progress Towards a Cure for HIV-1
Released: 13-Feb-2024 9:00 AM EST
New Trial Highlights Incremental Progress Towards a Cure for HIV-1
University of North Carolina School of Medicine

A new clinical trial, led by clinicians and researchers at the UNC School of Medicine, show that the combination of the drug vorinostat and immunotherapy may modestly shrink the latent HIV reservoir, but more work needs to be done in the field to create a cure.

Released: 12-Feb-2024 11:05 AM EST
Antibody drug conjugates make strides in ovarian cancer with recent FDA approval
University of California, Los Angeles (UCLA), Health Sciences

The UCLA team played a pivotal role in a clinical trial that led to the FDA granting accelerated approval of the first antibody drug conjugate (ADC), mirvetuximab soravtansine, for the treatment of platinum-resistant ovarian cancer.

Newswise: University Hospitals Now Offering FDA-Approved Medication for Treatment of Alzheimer’s Disease
Released: 9-Feb-2024 9:30 AM EST
University Hospitals Now Offering FDA-Approved Medication for Treatment of Alzheimer’s Disease
University Hospitals Cleveland Medical Center

University Hospitals Brain Health & Memory Center is now treating patients with LEQEMBI® (lecanemab), a Food and Drug Administration-approved medication for the treatment of Alzheimer’s disease.

Released: 8-Feb-2024 3:00 PM EST
Novel Treatment Regimen for FLT3-Mutated Acute Myeloid Leukemia Shows Promise in Roswell Park-Led Study
Roswell Park Comprehensive Cancer Center

Up to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene mutation, which is associated with a high risk of relapse and a very poor prognosis.

Newswise: 1920_cedars-sinai-accelerator.jpg?10000
Released: 8-Feb-2024 2:05 PM EST
Cedars-Sinai Introduces Dutch Health-Tech Startups to US Markets
Cedars-Sinai

Cedars-Sinai will host 10 Dutch health technology startups in Los Angeles to share best practices on bringing innovative ideas and products to the U.S. market.

Newswise: 1920_tricuspid-valve-smidt-heart-institute-cedars-sinai.jpg?10000
Released: 8-Feb-2024 1:05 PM EST
Smidt Heart Institute Physicians Advance Transcatheter Tricuspid Valve Replacement
Cedars-Sinai

Physicians in the Smidt Heart Institute at Cedars-Sinai have achieved two significant firsts: completing the institute’s 100th minimally invasive tricuspid valve replacement and performing the first-ever implantation of a new bioprosthetic tricuspid valve following its approval by the U.S. Food and Drug Administration (FDA).

Released: 8-Feb-2024 10:05 AM EST
CSOFT Health Sciences Releases MDR White Paper to Support EU Medical Device Compliance
CSOFT International

CSOFT Health Sciences, leaders in clinical trial translation, are pleased to announce the launch of their co-authored white paper for medical device manufacturers seeking re-certification under the updated EU Medical Device Regulation (EU MDR), in collaboration with partner organizations Gouya Insights and GCP-Service International Ltd. & Co.KG to jointly offer manufacturers an end-to-end platform for establishing conformity with policies set to take effect by January 2028.

Released: 8-Feb-2024 8:50 AM EST
Atlantic Health System Enrolls First U.S. Patient in Lupus Treatment Trial
Atlantic Health System

NJ-based Atlantic Health System is the first in the U.S. to enroll a patient in a study to examine the effectiveness of using Chimeric Antigen Receptor (CAR- T) cells in the treatment of the autoimmune disease lupus.

Newswise: Sara Federico, MD, named director of the Solid Tumor Division at St. Jude Children’s Research Hospital
Released: 7-Feb-2024 2:05 PM EST
Sara Federico, MD, named director of the Solid Tumor Division at St. Jude Children’s Research Hospital
St. Jude Children's Research Hospital

Established clinician researcher will focus on novel treatments and clinical trials for difficult-to-treat childhood cancers.

Released: 6-Feb-2024 10:05 AM EST
Moffitt Study Suggests Improvements Needed for Patient-Reported Outcome Data in Genitourinary Cancer Clinical Studies
Moffitt Cancer Center

In a recent study published in eClinicalMedicine, part of The Lancet Discovery Science, Moffitt Cancer Center researchers demonstrate that there is a significant unmet need for improved analyses and reporting of patient-reported outcomes in genitourinary cancer clinical trials.

Newswise: CHLA-Bedside-Piccolo-blog-shutterstock_2605724_1.jpg.webp?itok=eNRc1tL_
Released: 6-Feb-2024 9:00 AM EST
Team Brings Piccolo PDA Closure to the Bedside
Children's Hospital Los Angeles

Since its approval in 2019, the Amplatzer Piccolo Occluder has been a game-changer—allowing teams to close a patent ductus arteriosus (PDA) in premature babies in a minimally invasive way.But there’s one problem: Some babies are too sick to be moved to a catheterization lab for the procedure.

Not for public release

This news release is embargoed until 5-Feb-2024 5:00 PM EST Released to reporters: 30-Jan-2024 2:00 PM EST

A reporter's PressPass is required to access this story until the embargo expires on 5-Feb-2024 5:00 PM EST The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 2-Feb-2024 11:05 AM EST
Psychological care delivered over the phone is an effective way to combat loneliness and depression, according to a major new study
University of York

The study, led by a team based at the University of York and Hull York Medical School and at Tees, Esk and Wear Valleys NHS Foundation Trust, found levels of depression reduced significantly and the benefits were greater than those seen for antidepressants.

Released: 2-Feb-2024 11:05 AM EST
Speech Accessibility Project begins recruiting people who have had a stroke
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project has begun recruiting U.S. and Puerto Rican adults who have had a stroke.

   
Newswise: Promising heart drugs ID'd by cutting-edge combo of machine learning, human learning
Released: 1-Feb-2024 9:05 PM EST
Promising heart drugs ID'd by cutting-edge combo of machine learning, human learning
University of Virginia Health System

University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.

   
Newswise:Video Embedded live-event-nurses-the-most-trusted-profession-in-an-age-of-mistrust
VIDEO
Released: 1-Feb-2024 5:00 PM EST
VIDEO AND TRANSCRIPT: Nurses -- The Most Trusted Profession in an Age of Mistrust
Newswise

For 21 years, nurses have consistently been the most trusted profession, according to the yearly Gallup poll. (The new poll will be issued by the end of January). Dr Rushton, who specializes in burnout, will speak on trust, moral injury, and how nurses cope in this day and age.

Newswise: For World Cancer Day, Alliance for Cancer Care Equity Advocates to ‘Close the Care Gap’ as Observance is Honored with Congressional Resolution
Released: 1-Feb-2024 2:15 PM EST
For World Cancer Day, Alliance for Cancer Care Equity Advocates to ‘Close the Care Gap’ as Observance is Honored with Congressional Resolution
National Comprehensive Cancer Network® (NCCN®)

For World Cancer Day, February 4th, NCCN, ACS CAN, and NMQF are announcing three key areas of policy focus as part of the Alliance for Cancer Care Equity (ACCE) joint collaboration, including advancing diversity in clinical trials, improving cancer screening and early detection, and increasing access to patient navigation.

Released: 1-Feb-2024 8:05 AM EST
Clinical Trials of Sticky, Bone-Boosting Proteins Funded By Department Of Defense
The Fannie and John Hertz Foundation

A startup company, Theradaptive, founded by Hertz Fellow Luis Alvarez aims to revolutionize sports medicine, orthopedic surgery, dental implants and even cancer care through its uniquely engineered proteins.

Released: 31-Jan-2024 10:05 AM EST
UGA stroke treatment headed to clinical trial
University of Georgia

A new therapeutic for stroke based on University of Georgia research will soon enter clinical trials.

Newswise: RWJBarnabas Health and Rutgers Cancer Institute of New Jersey First in State offering Novel form of Liver Cancer Treatment
Released: 30-Jan-2024 2:05 PM EST
RWJBarnabas Health and Rutgers Cancer Institute of New Jersey First in State offering Novel form of Liver Cancer Treatment
Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, together with RWJBarnabas Health, has joined a select number of institutions nationwide that offer a specialized chemotherapy delivery system called hepatic artery infusion (HAI) therapy for patients with liver tumors.

Newswise: Subcutaneous Nivolumab as Effective as IV for Renal Cell Carcinoma — With Much Faster Treatment Time
26-Jan-2024 1:05 PM EST
Subcutaneous Nivolumab as Effective as IV for Renal Cell Carcinoma — With Much Faster Treatment Time
Roswell Park Comprehensive Cancer Center

Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.

23-Jan-2024 11:05 AM EST
Researchers Discover Why One Type of Chemotherapy Works Best in Bladder Cancer
Mount Sinai Health System

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system’s ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

Newswise: Digital pathology cleared for use in cancer screening programs
Released: 25-Jan-2024 11:05 AM EST
Digital pathology cleared for use in cancer screening programs
University of Warwick

New research funded by the National Institute for Health and Care Research (NIHR) has led to the UK government approving the use of digital pathology to help speed up analysis of cancer screening samples.

Released: 22-Jan-2024 8:05 AM EST
ProofPilot to Host "Protocol Bowl" at the 15th Annual SCOPE Summit
ProofPilot

Protocol BowProofPilot , the leading platform for clinical trial automation & guidance, today announced its "Protocol Bowl" event at the 15th Annual SCOPE Summit for clinical trial operations executives the day after Sunday's Big Game.

   
Released: 19-Jan-2024 9:05 AM EST
Wolters Kluwer honored with eight AJN Book of the Year award wins
Wolters Kluwer Health: Lippincott

vrClincals for Nursing and A Systematic Approach to Evaluation of Nursing Programs receive first place recognition in the annual awards from the American Journal of Nursing

Newswise: UTHealth Houston opens recruitment in RISE-UP clinical drug trial for people with sickle cell anemia
Released: 18-Jan-2024 6:05 PM EST
UTHealth Houston opens recruitment in RISE-UP clinical drug trial for people with sickle cell anemia
University of Texas Health Science Center at Houston

A medication that appeared to stabilize the function and shape of red blood cells in an earlier study for patients with sickle cell disease is now part of a Phase III clinical trial that is open for enrollment at UTHealth Houston.

Newswise: Researcher, Through Spinoff, Develops a Handheld White Blood Cell Tracker
Released: 18-Jan-2024 4:05 PM EST
Researcher, Through Spinoff, Develops a Handheld White Blood Cell Tracker
Rutgers University-New Brunswick

A Rutgers researcher, through his spinoff company, has led a team to design and test a device that quickly counts a person’s white blood cells with a single drop of blood, similar to the way glucometers rapidly scan for blood sugar levels. T

Released: 12-Jan-2024 10:15 AM EST
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the First in the Nation to Offer Patients a New Interventional Clinical Study
Hackensack Meridian Health

Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the first ALS care provider in the United States to offer patients a new interventional clinical study.

Released: 5-Jan-2024 2:05 PM EST
Novel Compound Protects Against Infection by Virus that Causes COVID-19, Preliminary Studies Show
Dana-Farber Cancer Institute

• Stapled lipopeptides successfully deter infection by the SARS-CoV-2 virus and reduce the severity of COVID-19 in tests with hamsters

Released: 5-Jan-2024 10:05 AM EST
Speech Accessibility Project begins recruiting people with ALS
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project has expanded its recruitment and is inviting U.S. and Puerto Rican adults living with amyotrophic lateral sclerosis to participate.

       
Released: 18-Dec-2023 9:30 PM EST
Toothbrushing tied to lower rates of pneumonia among hospitalized patients
Brigham and Women’s Hospital

Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients—and it comes with bristles on one end.

Not for public release

This news release is embargoed until 15-Dec-2023 6:30 PM EST Released to reporters: 14-Dec-2023 3:30 PM EST

A reporter's PressPass is required to access this story until the embargo expires on 15-Dec-2023 6:30 PM EST The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.



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