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Embargo will expire:
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Released to reporters:
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Embargo will expire:
23-Oct-2018 12:00 PM EDT
Released to reporters:
19-Oct-2018 5:05 PM EDT

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Embargo will expire:
23-Oct-2018 11:00 AM EDT
Released to reporters:
19-Oct-2018 1:05 PM EDT

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WilsonSimsMolTherapyimageOct2018.jpg

Article ID: 702488

Making Gene Therapy Delivery Safer and More Efficient

Perelman School of Medicine at the University of Pennsylvania

Viral vectors used to deliver gene therapies undergo spontaneous changes during manufacturing which affects their structure and function. As gene therapy approaches become more common for treating disease, managing consistency of the molecular makeup of the virus particles that deliver genes is a key concern in manufacturing on a larger scale.

Released:
19-Oct-2018 11:05 AM EDT
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Article ID: 702496

Father's Nicotine Exposure May Cause Problems in Future Generations of His Children

Florida State University

A new Florida State University College of Medicine study in mice produced results that suggest nicotine exposure in men could lead to cognitive deficits in their children and grandchildren. Further studies will be required to know if the same outcomes seen in mice would apply to humans.

Released:
19-Oct-2018 11:05 AM EDT
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Article ID: 702433

Tailor-Made Fish Help Explain Genetic Conditions in Children

Seattle Children's Hospital

At Seattle Children's Research Institute, scientists are genetically-engineering zebrafish to harbor human DNA mutations known to contribute congenital conditions in children.

Released:
18-Oct-2018 12:40 PM EDT
Embargo will expire:
25-Oct-2018 11:00 AM EDT
Released to reporters:
18-Oct-2018 11:05 AM EDT

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 25-Oct-2018 11:00 AM EDT

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  • Embargo expired:
    18-Oct-2018 11:00 AM EDT

Article ID: 702401

Scientists Uncover How Rare Gene Mutation Affects Brain Development and Memory

University of California, Irvine

Researchers from the University of California, Irvine School of Medicine, have found that a rare gene mutation alters brain development in mice, impairing memory and disrupting the communication between nerve cells. They also show memory problems could be improved by transplanting a specific type of nerve cell into the brain. The findings were published today in Neuron.

Released:
18-Oct-2018 9:10 AM EDT
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  • Embargo expired:
    18-Oct-2018 9:00 AM EDT

Article ID: 702172

Researchers Describe Novel Immune Syndrome

The Rockefeller University Press

Researchers from Australia and Japan have discovered a new human immunodeficiency syndrome in two patients on separate continents. The study, which will be published October 18 in the Journal of Experimental Medicine, reveals that a mutation in a gene called IKBKB disrupts the immune system, leading to excessive inflammation and the loss of both T and B white blood cells.

Released:
15-Oct-2018 9:45 AM EDT
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Article ID: 702403

Nanocages in the Lab and in the Computer: How DNA-Based Dendrimers Transport Nanoparticles

University of Vienna

How to create nanocages, i.e., robust and stable objects with regular voids and tunable properties? Short segments of DNA molecules are perfect candidates for the controllable design of novel complex structures. Physicists from the University of Vienna, the Technical University of Vienna, the Foschungszentrum Jülich in Germany and Cornell University in the U.

Released:
18-Oct-2018 7:05 AM EDT

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