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Study Finds Certain Genetic Test Not Useful in Predicting Heart Disease Risk

Vanderbilt University Medical Center

A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.

Channels: All Journal News, Cardiovascular Health, Genetics, Heart Disease, Public Health, JAMA, Staff Picks,

Released:
21-Feb-2020 10:25 AM EST
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Coriell Researchers Identify SNP Associated with Obesity Risk

Coriell Institute for Medical Research

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person’s risk for the disease. Coriell researchers have found a new genetic indicator of obesity risk and bolstered the understood importance of one gene’s role in obesity risk.

Channels: Genetics, Military Health, Obesity, Public Health, All Journal News, Personalized Medicine,

Released:
21-Feb-2020 8:00 AM EST
Research Results
Embargo will expire:
26-Feb-2020 12:05 AM EST
Released to reporters:
20-Feb-2020 4:30 PM EST

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Research Results
Newswise: Earliest interbreeding event between ancient human populations discovered
  • Embargo expired:
    20-Feb-2020 2:00 PM EST

Earliest interbreeding event between ancient human populations discovered

University of Utah

The study documented the earliest known interbreeding event between ancient human populations— a group known as the “super-archaics” in Eurasia interbred with a Neanderthal-Denisovan ancestor about 700,000 years ago. The event was between two populations more distantly related than any other recorded.

Channels: All Journal News, Archaeology and Anthropology, Evolution and Darwin, Genetics, Paleontology, African News, Staff Picks,

Released:
20-Feb-2020 11:50 AM EST
Research Results
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Colorectal cancer partner-in-crime identified

Hokkaido University

A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.

Channels: All Journal News, Cancer, Genetics, Immunology,

Released:
20-Feb-2020 12:15 PM EST
Research Results
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  • Embargo expired:
    20-Feb-2020 11:00 AM EST
Released:
19-Feb-2020 4:35 PM EST
Research Results
Newswise: A deep dive into cellular aging
  • Embargo expired:
    20-Feb-2020 8:00 AM EST

A deep dive into cellular aging

Sanford Burnham Prebys Medical Discovery Institute

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell’s nucleus—and identified an FDA-approved drug that helped suppress the damaging effects of the condition in cells and mice. The discovery, published in Genes & Development, could lead to treatments that promote healthy aging or prevent age-associated diseases such as cancer, Alzheimer’s disease, heart disease and more.

Channels: Aging, All Journal News, Genetics, Grant Funded News,

Released:
18-Feb-2020 5:10 PM EST
Research Results

Random gene pulsing generates patterns of life

University of Cambridge

A team of Cambridge scientists working on the intersection between biology and computation has found that random gene activity helps patterns form during development of a model multicellular system.

Channels: All Journal News, Biotech, Cell Biology, Genetics, Nature (journal),

Released:
19-Feb-2020 10:45 AM EST
Research Results
Newswise: Neighborhood Features and One’s Genetic Makeup Interact to Affect Cognitive Function

Neighborhood Features and One’s Genetic Makeup Interact to Affect Cognitive Function

Florida Atlantic University

Few studies have examined how the neighborhood’s physical environment relates to cognition in older adults. Researchers categorized 4,716 individuals by apolipoprotein E (APOE) genotype – a genetic risk factor for Alzheimer’s disease (AD) to determine if there are cognitive benefits of living in neighborhoods with greater access to social, walking and retail destinations. Results showed that the positive influence of neighborhood environments on cognition are strongest among those who are at the lowest risk for AD, specifically APOE ε2 carriers.

Channels: Aging, All Journal News, Alzheimer's and Dementia, Cognition and Learning, Environmental Science, Neuro, Genetics,

Released:
19-Feb-2020 8:30 AM EST
Research Results
Newswise: New Research Links Genetics and MS Severity, Offers Innovative Treatment Ideas to Combat MS and Other Neurodegenerative Diseases

New Research Links Genetics and MS Severity, Offers Innovative Treatment Ideas to Combat MS and Other Neurodegenerative Diseases

Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

Dr. Peter Calabresi, professor of Neurology and Neuroscience at the Johns Hopkins School of Medicine and Director of the Johns Hopkins Multiple Sclerosis (MS) Center, will present his team’s discovery of a possible link between severe damage and C3 and C1q gene variants, and how this information could lead to improvements in the ways MS and other neurodegenerative diseases are treated, during his keynote Kenneth P. Johnson Memorial Lecture on the opening day of the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2020.

Channels: Genetics, Neuro, All Journal News,

Released:
18-Feb-2020 3:25 PM EST
Research Results


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