This experiment had a good chance of crashing. Instead, it delivered whopping evidence to corroborate that the translational system, which makes life out of our genes, would have thrived basically as it is today 4 billion years ago at the earliest foundations of life on Earth.
In a study published today in the journal Cell, University of California, Irvine researchers reported that they have accelerated and simplified directed evolution by having live cells do most of the heavy lifting. By inserting a specially engineered DNA replication system into yeast, the scientists were able to coax selected genes to rapidly and stably mutate and evolve as the host yeast cells reproduced.
The Endocrine Society expressed concerns that the European Commission’s communication on endocrine-disrupting chemicals (EDCs) released Wednesday fails to address the urgent need to protect children and other vulnerable populations from EDC exposure.
After eight years of study, a team of researchers from the University of California San Diego and Johns Hopkins University published new findings about how to read the body’s histone code in the Nov. 7 issue of Science Advances. The findings answer a key question in the dynamic research area of epigenetics—adding chemical tags to DNA and histone proteins to alter cell functions without changing DNA sequence. Understanding the fundamental principles of how epigenetic information is transduced in the cell eventually could lead to developing new drugs for fighting diseases like cancer.