Credit: The Salk Institute for Biological Studies
The new study shows that gene-editing technologies are specific to their targets and do not introduce harmful mutations, clearing the way for the development of safe therapies in the clinic. The left panel shows misshapen nuclear envelopes (red) from induced pluripotent stem cells derived from cells with Parkinson’s disease (DNA in blue). The right panel shows similarly induced cells that have been gene-edited to restore the cells.