Credit: UAB News
UAB scientists including Anath Shalev (right), director of UAB's Comprehensive Diabetes Center, have uncovered that the drug verapamil, which is widely used to treat high blood pressure, irregular heartbeat and migraine headaches, can lower TXNIP levels in pancreatic beta cells — to the point that, when mouse models with established diabetes and blood sugars above 300 milligrams per deciliter were treated with verapamil, the disease was eradicated.