Credit: Curtis Brandt/Paul Kaufman, University of Wisconsin-Madison
In an effort to improve gene transfer to treat the blinding disease glaucoma, the front of an untreated eye (left) is compared to an eye (right) pretreated with a gene delivery enhancer. The green marker reveals the expression of a new gene in the trabecular meshwork, which drains fluid from the eye and is usually blocked in glaucoma. The green band resulting from gene transfer is denser and wider in the enhancer-treated eye.