Credit: Credit: Wenxin Ma, M.D., Ph.D., and Wai Wong, M.D., Ph.D., National Eye Institute
In healthy retina (left), microglia (green) demonstrate a branched structure that covers the retina. Without TGF-beta signaling (right), microglia lose their branched structure, and attach to blood vessels (white). Müller glia become abnormal and acquire activation markers (red).