Credit: Sharma et. al. (2020) Biochem Biophys Res Comms
A group of SARS-CoV-2 virus-like particles are shown in panel (A) on a glass surface in room temparture. The color scale describes the height of each particle—red is the tallest and dark blue is the flattest. (B) Virus-like particles imaged at about 93 degrees F (34 degrees C) under dry conditions. There is no discernable features of the particles in panel A, indicating the particle structure degraded. (C) The virus-like particles that were incubated at about 93 degrees F (34 degrees C) in a buffer solution, and imaged at room temperature. The particles are more consistent with A, but still reveal widespread structural degradation.