Credit: Cell Reports Medicine
Researchers at Icahn Mount Sinai in New York identified 35 genes that could be used as biomarkers to potentially diagnose patients with long-term Lyme disease (LTLD). The findings may also lead to new therapeutic targets for the hard-to-diagnose disease with limited treatment options. The study is the first to use transcriptomics in patients with post-treatment Lyme disease to determine whether there is a specific immune response. A gene panel that measures the expression of genes the investigators identified could be developed as a diagnostic.