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    • 2020-09-30 11:05:53
    • Article ID: 738901

    Science Snapshots September 2020

    • Credit: Near-field scanning microscope image of nanocircuits “written” into a 2D device made of boron nitride and graphene.

      Alex Zettl/Berkeley Lab

    An Innovative Pattern: Scientists Rewrite Rules for 2D Electronics
    New technique could lead to rewritable memory devices and low-power electronics
    By Theresa Duque 

    A research team led by Alex Zettl, senior faculty scientist in Berkeley Lab’s Materials Sciences Division and professor of physics at UC Berkeley, has developed a new technique for fabricating tiny circuits from ultrathin materials for next-generation electronics, such as rewritable, low-power memory circuits. Their findings were reported in the journal Nature Electronics.

    Using the nanofabrication facility at the Molecular Foundry, the researchers prepared two different 2D devices known as van der Waals heterostructures: one by sandwiching graphene between two layers of boron nitride; and another by sandwiching molybdenum disulfide.

    When applying a fine electron beam to the boron-nitride “sandwiches,” the researchers demonstrated that they can “write” nanoscale conducting channels, or nanocircuits, into the core “active” layer by controlling the intensity of electron beam exposure while properly controlling a back-gate electric field.

    When written into the graphene or molybdenum disulfide layer, these nanocircuits allow high densities of electrons, or quasiparticles called holes, to accumulate and move through the semiconductor along narrow predetermined tracks at ultrahigh speeds with few collisions – like cars racing through a freeway within inches of each other without crashing or stalling.

    The researchers also found that reapplying the electron beam with a special back-gate to the 2D materials can erase nanocircuits that have already been written – or write additional or different circuits in the same device, which suggests that the technique has great potential for next-generation reconfigurable 2D electronics.

    Importantly, the researchers demonstrated that the material’s conducting states and ultrahigh electronic mobility persists even after the electron beam and the back-gate have been removed. This finding is critical to many applications, including energy-efficient nonvolatile memory devices that do not require constant power to retain data, said lead author Wu Shi, a project scientist in Berkeley Lab’s Materials Sciences Division and the Zettl Lab at UC Berkeley.

    Synthetic Pathways Turn Plants into Biofactories for New Molecules
    Scientists demonstrate a method for sustainably producing a wide range of compounds
    By Emily Scott

    Plants can produce a wide range of molecules, many of which help them fight off harmful pests and pathogens. Biologists have harnessed this ability to produce many molecules important for human health — aspirin and the antimalarial drug artemisinin, for example, are derived from plants.

    Now, scientists at the Joint BioEnergy Institute (JBEI) are using synthetic biology to give plants the ability to create molecules never seen before in nature. New research led by Patrick Shih, director of Plant Biosystems Design at JBEI, and Beth Sattely of Stanford University describes success in swapping enzymes between plants to engineer new synthetic metabolic pathways. These pathways gave plants the ability to create new classes of chemical compounds, some of which have enhanced properties.

    “This is a demonstration of how we can begin to start rewiring and redesigning plant metabolism to make molecules of interest for a range of applications,” Shih said.

    Engineering plants to make new molecules themselves provides a sustainable platform to produce a wide range of compounds. One of the compounds the researchers were able to create is comparable to commercially used pesticides in their effectiveness, while others may have anti-cancer properties. The long-term goal is to engineer plants to be biofactories of molecules such as these, bypassing the need to externally spray pesticides or synthesize therapeutic molecules in a lab.

    “That’s the motivation for where we could go,” Shih said. “We want to push the boundaries of plant metabolism to make compounds we’ve never seen before.”

    JBEI is a DOE Bioenergy Research Center supported by DOE’s Office of Science.

    Transforming Waste into Bio-Based Chemicals
    Researchers make important step towards converting a material in plant cell walls into eco-friendly ionic liquids
    By Emily Scott

    Researchers at Berkeley Lab have transformed lignin, a waste product of the paper industry, into a precursor for a useful chemical with a wide range of potential applications.

    Lignin is a complex material found in plant cell walls that is notoriously difficult to break down and turn into something useful. Typically, lignin is burned for energy, but scientists are focusing on ways to repurpose it. 

    In a recent study, researchers demonstrated their ability to convert lignin into a chemical compound that is a building block of bio-based ionic liquids. The research was a collaboration between the Advanced Biofuels and Bioproducts Process Development Unit, the Joint BioEnergy Institute (both established by the Department of Energy and based at Berkeley Lab), and the Queens University of Charlotte. 

    Ionic liquids are powerful solvents/catalysts used in many important industrial processes, including the production of sustainable biofuels and biopolymers. However, traditional ionic liquids are petroleum-based and costly. Bio-based ionic liquids made with lignin, an inexpensive organic waste product, would be cheaper and more environmentally friendly.

    “This research brings us one step closer to creating bio-based ionic liquids,” said Ning Sun, the study’s co-corresponding author. “Now we just need to optimize and scale up the technology.”

    According to Sun, bio-based ionic liquids also have a broad range of potential uses outside of industry. “We now have the platform to synthesize bio-based ionic liquids with different structures that have different applications, such as antivirals,” Sun said.

    This research was funded by DOE’s Bioenergy Technologies Office through the Technology Commercialization Fund. 

    Providing New Technologies for Vaccine Development 
    Berkeley Lab scientists aid in quest to design novel vaccine scaffolds
    By Lida Gifford 

    Vaccines, which help the body recognize infectious microorganisms and stage a stronger and faster response, are made up of proteins that are specific to each type of microorganism. In the case of a virus, viral proteins – or antigens – can sometimes be attached to a protein scaffold to help mimic the shape of the virus and elicit a stronger immune response. Using scaffolds to approximate the natural configuration of the antigen is an emerging approach to vaccine design.

    A team of scientists led by David Baker at the University of Washington developed a method to design artificial proteins to serve as a framework for the viral antigens. Their study was published recently in the journal eLife. Berkeley Lab scientists collected data at the Advanced Light Source to visualize the atomic structure and determine the dynamics of the designed scaffolds. 

    “When bound, the scaffolds assume predicted geometries, which more closely approximate the virus shape and thereby maximize the immune response,” said Banu Sankaran, a research scientist in the Molecular Biophysics and Integrated Bioimaging (MBIB) Division. “It was exciting to collaborate on this method to predictably design frameworks, which could lead to more effective vaccines, especially for viruses that we don’t have a scaffold for.”

    The team also included Peter Zwart, MBIB staff scientist; small angle X-ray scattering data were collected at the SIBYLS beamline by MBIB’s Kathryn Burnett and Greg Hura.

    The Advanced Light Source is a DOE Office of Science user facility.

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    A first-of-its-kind catalyst mimics natural processes to break down plastic and produce valuable new products

    A first-of-its-kind catalyst mimics natural processes to break down plastic and produce valuable new products

    A team of scientists led by the U.S. Department of Energy's Ames Laboratory has developed a first-of-its-kind catalyst that is able to process polyolefin plastics, types of polymers widely used in things like plastic grocery bags, milk jugs, shampoo bottles, toys, and food containers.

    A new approach boosts lithium-ion battery efficiency and puts out fires, too

    A new approach boosts lithium-ion battery efficiency and puts out fires, too

    This new technology addresses two major goals of battery research: extending the driving range of electric vehicles and reducing the danger that laptops, cell phones and other devices will burst into flames.

    Berkeley Lab Scientists Contribute to New Exploration of Higgs Boson Interactions

    Berkeley Lab Scientists Contribute to New Exploration of Higgs Boson Interactions

    A new analysis, featuring important contributions by Berkeley Lab scientists, strongly supports the hypothesis that the Higgs boson interacts with muons, which are heavier siblings of electrons and the lightest particles yet to reveal evidence for these interactions.

    New Algorithm Sharpens Focus of World's Most Powerful Microscopes

    New Algorithm Sharpens Focus of World's Most Powerful Microscopes

    Scientists have shown that an algorithm added to image processing software can improve the resolution and accuracy of cryo-electron microscopes, which are one of the most crucial tools in microbiology and medical research.

    An Electrical Trigger Fires Single, Identical Photons

    An Electrical Trigger Fires Single, Identical Photons

    The precisely controlled photon source, made from an atomically thin semiconducting material, could aid the development of advanced quantum communication

    First detailed look at how molecular Ferris wheel delivers protons to cellular factories

    First detailed look at how molecular Ferris wheel delivers protons to cellular factories

    All cells with nuclei, from yeast to humans, use molecular machines called protons to regulate the acidity of compartments called organelles where various types of work are done. A new study reveals a key step in how these Ferris wheel-like pumps operate.

    Argonne develops unprecedented long-term wildfire prediction model

    Argonne develops unprecedented long-term wildfire prediction model

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    Study Finds 'Missing Link' in the Evolutionary History of Carbon-Fixing Protein Rubisco

    Study Finds 'Missing Link' in the Evolutionary History of Carbon-Fixing Protein Rubisco

    The discovery of a primitive form of rubisco, a photosynthetic enzyme, will help scientists understand how carbon-fixing organisms led to the planet's oxygenation and how modern

    Story Tips: Remote population counting, slowing corrosion and turning down the heat

    Story Tips: Remote population counting, slowing corrosion and turning down the heat

    ORNL story tips: Remote population counting, slowing corrosion and turning down the heat

    Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet

    Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet

    Researchers generated genome sequences for nearly 600 green millet plants and released a very high-quality reference S. viridis genome sequence Analysis of these plant genome sequences also led them to identify for the first time in wild populations a gene related to seed dispersal.


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    Who Will Get the Prize for Better Hurricane Monitoring?

    Who Will Get the Prize for Better Hurricane Monitoring?

    The Ocean Observing Prize seeks competitors for an incentive prize program to help inventors advance new concepts for marine energy technologies that can power ocean observing systems. This phase focuses on observing platforms that host instruments that can provide better data regarding hurricane formation.

    Berkeley Lab Names Noel Bakhtian to Lead New Energy Storage Center

    Berkeley Lab Names Noel Bakhtian to Lead New Energy Storage Center

    Berkeley Lab has appointed Noel Bakhtian, previously a senior policy adviser in the White House Office of Science and Technology (OSTP) and currently director of the Center for Advanced Energy Studies (CAES) at Idaho National Laboratory, as its inaugural director of the Berkeley Lab Energy Storage Center.

    CERN Senior Fellow Dorota Grabowska Receives Leona Woods Lectureship Award

    CERN Senior Fellow Dorota Grabowska Receives Leona Woods Lectureship Award

    Dorota Grabowska, a senior fellow in the department of theoretical physics at CERN, Europe's particle physics laboratory, has been named a recipient of the Leona Woods Distinguished Postdoctoral Lectureship Award. The award was established by the physics department at the U.S. Department of Energy's Brookhaven National Laboratory in honor of renowned physicist Leona Woods to celebrate the scientific accomplishments of outstanding female physicists and physicists from other under-represented minority groups, including the LGBTQ community--and to promote diversity and inclusion in the department.

    Process to recover metals from batteries licensed by Momentum Technologies

    Process to recover metals from batteries licensed by Momentum Technologies

    Momentum Technologies Inc., a Dallas, Texas-based materials science company that is focused on extracting critical metals from electronic waste, has licensed an Oak Ridge National Laboratory process for recovering cobalt and other metals from spent lithium-ion batteries.

    PPPL physicist wins third place at Innovation Forum for advanced liquid centrifuge invention

    PPPL physicist wins third place at Innovation Forum for advanced liquid centrifuge invention

    Physicist Erik Gilson won third place at the Princeton University Keller Center's 15th Annual Innovation Forum for his invention with a team of PPPL researchers of an advanced liquid centrifuge.

    Oak Ridge National Laboratory, UT's Tony Schmitz elected to ASPE College of Fellows

    Oak Ridge National Laboratory, UT's Tony Schmitz elected to ASPE College of Fellows

    Tony Schmitz, joint faculty researcher in machining and machine tools at Oak Ridge National Laboratory, and mechanical, aerospace and biomedical engineering professor at the University of Tennessee, Knoxville, has been elected to the College of Fellows of the American Society for Precision Engineering.

    Coming Down the Pike: Long-Haul Trucks Powered by Hydrogen Fuel Cells

    Coming Down the Pike: Long-Haul Trucks Powered by Hydrogen Fuel Cells

    The Department of Energy has announced several major investments to take hydrogen fuel cells to the next level, and Lawrence Berkeley National Laboratory (Berkeley Lab) is set to play a leading role in providing the scientific expertise to help realize DOE's ambitious goals.

    Media Advisory: Epic Arctic Science Mission End Briefing

    Journalists are invited to join an October 12 Zoom media briefing with U.S. scientists and agency experts involved in the yearlong international research expedition MOSAiC: Multidisciplinary Drifting Observatory for the Study of Arctic Climate.

    Jennifer Doudna Wins 2020 Nobel Prize in Chemistry

    Jennifer Doudna Wins 2020 Nobel Prize in Chemistry

    Biochemist Jennifer Doudna, a professor at UC Berkeley and faculty scientist at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), is co-winner of the 2020 Nobel Prize in Chemistry for "the development of a method for genome editing."

    Path-setting theoretical physicist Elena Belova elected an APS Fellow

    Path-setting theoretical physicist Elena Belova elected an APS Fellow

    Profile of PPPL physicist Elena Belova, a pioneer in developing hybrid simulation codes in fusion and space plasmas, who has been elected a Fellow of the American Physical Society.


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    Harvesting Energy from Light using Bio-inspired Artificial Cells

    Harvesting Energy from Light using Bio-inspired Artificial Cells

    Scientists designed and connected two different artificial cells to each other to produce molecules called ATP (adenosine triphosphate).

    Engineering Living Scaffolds for Building Materials

    Engineering Living Scaffolds for Building Materials

    Bone and mollusk shells are composite systems that combine living cells and inorganic components. This allows them to regenerate and change structure while also being very strong and durable. Borrowing from this amazing complexity, researchers have been exploring a new class of materials called engineered living materials (ELMs).

    Excavating Quantum Information Buried in Noise

    Excavating Quantum Information Buried in Noise

    Researchers developed two new methods to assess and remove error in how scientists measure quantum systems. By reducing quantum "noise" - uncertainty inherent to quantum processes - these new methods improve accuracy and precision.

    How Electrons Move in a Catastrophe

    How Electrons Move in a Catastrophe

    Lanthanum strontium manganite (LSMO) is a widely applicable material, from magnetic tunnel junctions to solid oxide fuel cells. However, when it gets thin, its behavior changes for the worse. The reason why was not known. Now, using two theoretical methods, a team determined what happens.

    When Ions and Molecules Cluster

    When Ions and Molecules Cluster

    How an ion behaves when isolated within an analytical instrument can differ from how it behaves in the environment. Now, Xue-Bin Wang at Pacific Northwest National Laboratory devised a way to bring ions and molecules together in clusters to better discover their properties and predict their behavior.

    Tune in to Tetrahedral Superstructures

    Tune in to Tetrahedral Superstructures

    Shape affects how the particles fit together and, in turn, the resulting material. For the first time, a team observed the self-assembly of nanoparticles with tetrahedral shapes.

    Tracing Interstellar Dust Back to the Solar System's Formation

    Tracing Interstellar Dust Back to the Solar System's Formation

    This study is the first to confirm dust particles pre-dating the formation of our solar system. Further study of these materials will enable a deeper understanding of the processes that formed and have since altered them.

    Investigating Materials that Can Go the Distance in Fusion Reactors

    Investigating Materials that Can Go the Distance in Fusion Reactors

    Future fusion reactors will require materials that can withstand extreme operating conditions, including being bombarded by high-energy neutrons at high temperatures. Scientists recently irradiated titanium diboride (TiB2) in the High Flux Isotope Reactor (HFIR) to better understand the effects of fusion neutrons on performance.

    Better 3-D Imaging of Tumors in the Breast with Less Radiation

    Better 3-D Imaging of Tumors in the Breast with Less Radiation

    In breast cancer screening, an imaging technique based on nuclear medicine is currently being used as a successful secondary screening tool alongside mammography to improve the accuracy of the diagnosis. Now, a team is hoping to improve this imaging technique.

    Microbes are Metabolic Specialists

    Microbes are Metabolic Specialists

    Scientists can use genetic information to measure if microbes in the environment can perform specific ecological roles. Researchers recently analyzed the genomes of over 6,000 microbial species.


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