Meet the molecule that helps stressed cells decide between life and death

St. Jude Children’s Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.
11-Sep-2019 1:05 PM EDT Add to Favorites

World’s largest and most powerful Nuclear Magnetic Resonance Spectrometer arrives at St. Jude Children’s Research Hospital

St. Jude Children’s Research Hospital has acquired the first Ascend 1.1 GHz Nuclear Magnetic Resonance Spectrometer, the largest and most powerful device of its kind from Massachusetts-based Bruker Corp.
6-Sep-2019 10:20 AM EDT Add to Favorites

Researchers Move Beyond Sequencing and Create a 3D Genome

St. Jude Children’s Research Hospital scientists have taken whole genome sequencing to the next level by creating a 3D map of the genome to better understand development and disease
3-Sep-2019 4:20 PM EDT Add to Favorites

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma

A report from St. Jude Children’s Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents. The work appears as an advance online publication today in JAMA...
24-Jul-2019 2:05 PM EDT Add to Favorites

To Understand a Childhood Brain Tumor, Researchers Turn to Single-Cell Analysis

Investigators at St. Jude Children’s Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor. The work also...
23-Jul-2019 4:00 PM EDT Add to Favorites

Rare inherited enzyme disorder yields insight into fibrosis

St. Jude investigators have discovered an association between a deficiency in the enzyme neuraminidase 1 and the build-up of connective tissue in organs such as the muscle, kidney, liver, heart and lungs.
17-Jul-2019 2:00 PM EDT Add to Favorites

Pathway discovered that prevents buildup of Alzheimer’s protein

St. Jude Children’s Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer’s disease. The report appeared online today in the journal Cell.
24-Jun-2019 12:05 PM EDT Add to Favorites

Researchers discover key genetic trigger that compromises cancer immunotherapy

An international research team has discovered a gene that triggers a process called “exhaustion” in the immune T cells used to battle cancer in immunotherapy. The gene, called Tox, launches a process that remodels the cells’ machinery to...
17-Jun-2019 10:05 AM EDT Add to Favorites

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