High doses of acetaminophen can damage the liver. Researchers have found a new mechanism by which an acetaminophen breakdown product can impair liver proteins. The compound activates a protein modification pathway called glutathionylation. The...
11-Oct-2018 12:05 PM EDT Add to Favorites
Using a statistical technique called network meta-analysis, researchers have combined the results of dozens of studies of dietary oils to identify those with the best effect on patients' LDL cholesterol and other blood lipids.
9-Oct-2018 11:05 AM EDT Add to Favorites
In a new study published in the Journal of Biological Chemistry, researchers at Imperial College London and the Francis Crick Institute report some of the details of how Salmonella shuts down an immune pathway after infection.
28-Sep-2018 2:05 PM EDT Add to Favorites
A quantitative proteomic study of how influenza virus affects lung-derived cell lines found that protein synthesis machinery relocates to the autophagosome in infected cells.
28-Sep-2018 12:05 PM EDT Add to Favorites
New clinical and molecular evidence shows that fertility outcomes are improved when semen samples are collected after just a few hours of abstinence.
17-Sep-2018 10:05 AM EDT Add to Favorites
A team of researchers at the Lerner Research Institute of the Cleveland Clinic has now solved a long-standing puzzle by identifying the protein that "chaperones" free heme in cells. The findings are published in the Journal of Biological Chemistry.
14-Sep-2018 2:05 PM EDT Add to Favorites
Three recent studies dig into how nonalcoholic fatty liver disease affects mitochondria in the liver: how mitochondrial energy production stutters and fails as the disease progresses, and how this affects the organ’s use of nutrients to produce...
14-Sep-2018 10:05 AM EDT Add to Favorites
Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme implicated in a number of...
6-Sep-2018 2:05 AM EDT Add to Favorites
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